Results 111 to 120 of about 2,770 (195)

Effectiveness and irritability study of glabridin nanoemulsion with oleic acid-EVO oil and oleic acid-palm oil as an oil phase

Journal of Research in Pharmacy
Glabridin, an isoflavan primarily found in licorice extract, is widely recognized for its skin-lightening properties. However, its effective use is limited by poor solubility, low stability, and inadequate skin penetration.
Putu Devi Febrina Suryandari, T. Erawati, Noorma Rosita   +2 more
semanticscholar   +1 more source

An Evaluation of The Effects of Glabridin, Dexamethasone, and Iberiotoxin on Liver Injury in A Rat Model of Bleomycin-Induced Pulmonary Fibrosis

Neuro-Cell Molecular Research
This study investigated the potential protective effects of glabridin (Gla), dexamethasone (DEX), and iberiotoxin (Ibx), a BKCa channel inhibitor, against liver damage in a bleomycin (BLM)-induced pulmonary fibrosis model. Thirty-six female Wistar Albino
Elfide Gizem Bakırhan
semanticscholar   +1 more source

Glabridin reduces neuroinflammation by modulating inflammatory signals in LPS-induced in vitro and in vivo models

InflammoPharmacology
Chronic neuroinflammation has become one of the important causes of common neurodegeneration disease. Therefore, the target of this study was to explore the protective action of glabridin on lipopolysaccharide (LPS)-induced neuroinflammation in vivo and ...
Jiyu Weng, Ying Wang, Z. Tan, Yanghe Yuan, Shiyuan Huang, Zexi Li, Yi-Ming Li, Lanyue Zhang, Zhiyun Du   +8 more
semanticscholar   +1 more source

Glabridin from Glycyrrhizha glabra Linn. as multi-targeted therapeutic agent against Alzheimer’s disease: an in-silico study

International Journal For Multidisciplinary Research
Alzheimer’s disease (AD) is a progressive neurodegenerative disease mainly occurring in old age adults. Its pathophysiology involves accumulation of tau protein in brain leading to the intracellular neurofibrillary tangles (NFTs) and amyloid β protein ...
V. V.
semanticscholar   +1 more source

Glabridin induced cell apoptosis in HL-60 and MV4-11 cells.

, 2014
(A) HL-60 and MV4-11 cells were incubated for 18 h in the absence of serum and then treated with indicated concentrations of glabridin for 24 h, after which the cells were stained with PI, and analyzed for DNA content by flow cytometry.
Ming-Ju Hsieh (184855), Hui-Yu Chen (572979), Pei-Ching Hsiao (456690), Shun-Fa Yang (155103), Ming-Hsien Chien (155089), Hsin-Lien Huang (572978)   +5 more
core   +1 more source

Glabridin Inhibits Migration, Invasion, and Angiogenesis of Human Non–Small Cell Lung Cancer A549 Cells by Inhibiting the FAK/Rho Signaling Pathway

, 2011
This study reports the antimigration, anti-invasive effect of glabridin, a flavonoid obtained from licorice, in human non–small cell lung cancer A549 cells.
Ya-Ling Hsu, Po-Lin Kuo, Ling-Yu Wu, Chi-Tun Lien, Ying-Ming Tsai, Jen-Yu Hung, Chih-Jen Yang, Yu-Chieh Tsai, Ming-Shyan Huang   +8 more
core   +1 more source

Glabridin inhibits proliferation and migration in hepatocellular carcinoma by regulating multi-targets.

Journal of Ethnopharmacology
ETHNOPHARMACOLOGICAL RELEVANCE Glycyrrhiza uralensis Fisch. (GC) is widely utilized in traditional Chinese medicine (TCM) for its properties in Qi tonification, heat clearing, and detoxification.
Fei Wang, Chong Yuan, Yi Lu, Mojiao Wu, He-Zhen Wu, Yifei Liu, Yanfang Yang   +6 more
semanticscholar   +1 more source

Advancing the Identification of Bioactive Molecules and the Construction of a Synergistic Drug Delivery System in Combating Lung Injury

Advanced Science
In recent years, pneumonia caused by multiple viruses has posed a significant threat to public health, particularly affecting vulnerable populations such as the elderly and immunocompromised individuals.
Jianhong Qi, Yanxia Wang, Huan Chen, Kaitian Wu, Pei Zhou, Yue Dou, Bingqi Xiong, Wei Zhou   +7 more
doaj   +1 more source

Glabridin Plays Dual Action to Augment the Efficacy and Attenuate the Hepatotoxicity of Methotrexate in Arthritic Rats

Glabridin is chemically an isoflavane class of natural phenols and is found mainly in the roots of Glycyrrhiza glabra. It has several beneficial pharmacological actions for the management of inflammatory disorders as well as can counteract drug-induced ...
Dilpreet Kour (10872766), Bhavna Vij (11751399), Utpal Nandi (4656142), Mahir Bhardwaj (12503355), Sumit Dhiman (12342841), Amit Kumar (81180), Ajay Kumar (192967), Ashish Dogra (8356386)   +7 more
core   +1 more source

In vitro and in vivo neuroprotective effect and mechanisms of glabridin, a major active isoflavan from Glycyrrhiza glabra (licorice)

, 2008
Stroke is a life-threatening disease characterized by rapidly developing clinical signs of focal or global disturbance of cerebral function due to cerebral ischemia.
Yaomin Du (20006340), Charlie Xue (8797853), Zhi-Wei Zhou (283143), Jun Liang (251318), Shufeng Zhou (398572), Xue-Qing Yu (11865637), Chun Li (57810)   +6 more
core