Results 91 to 100 of about 2,770 (195)

Glabridin attenuates airway inflammation and hyperresponsiveness in a mice model of ovalbumin-induced asthma

open access: yes, 2020
Asthma is an inflammatory disease of the airways of the lungs, which is characterized by airflow obstruction and bronchospasms. Glabridin is a major flavonoid, especially found in root of Glycyrrhiza glabra, and has several pharmacological activities ...
Tosun, E.M.   +5 more
core   +1 more source

The Combinatory Effects of Glabridin and Tamoxifen on Ishikawa and MCF-7 Cell Lines

open access: yesNatural Product Communications, 2015
Estrogen replacement therapy is commonly used to replace the loss of estrogen in post-menopausal women. However, it is not suitable to be used in women taking tamoxifen as both of the drugs increase the risk of endometrial cancer.
Soe Hui Jen   +2 more
doaj   +1 more source

Glabridin Attenuates the Retinal Degeneration Induced by Sodium Iodate In Vitro and In Vivo

open access: yesFrontiers in Pharmacology, 2020
BackgroundAge-related macular degeneration (AMD) is one of the major causes of blindness in the elderly over the age of 60. AMD is divided into dry AMD and wet AMD.
Kaung Htet Aung   +5 more
doaj   +1 more source

Pharmacological Mechanisms of Phytochemicals and Pharmaceutical Agents in Protecting Against Methotrexate‐Induced Liver Injury

open access: yesOxidative Medicine and Cellular Longevity, Volume 2026, Issue 1, 2026.
Methotrexate (MTX) is a widely used chemotherapeutic and immunosuppressive agent for treating various malignancies, autoimmune diseases (AIDs), and inflammatory disorders. Despite its therapeutic efficacy, long term or high‐dose MTX treatment is associated with a significant risk of hepatotoxicity, leading to MTX‐induced liver injury (MTX‐LI).
Bushra Zia   +6 more
wiley   +1 more source

Introducing the glycyrrhizic acid and glabridin rich genotypes from the cultivated Iranian licorice (Glycyrrhiza glabra L.) populations to exploit in production systems

open access: yesScientific Reports
Currently, the stable, uniform, and highly efficient production of raw materials for pharmaceutical companies has received special attention. To meet these criteria and reduce harvesting pressure on the natural habitats of licorice (Glycyrrhiza glabra L.)
H. Esmaeili   +3 more
semanticscholar   +1 more source

Cardiovascular protective effect of glabridin: Implications in LDL oxidation and inflammation

open access: yes, 2015
Atherosclerosis is one of the most common causes of death in Western countries and now considered as a chronic inflammatory disease in broad outline.
Ki Hwan Park   +7 more
core   +1 more source

Fungicidal Activity and Mechanism of Action of Glabridin from Glycyrrhiza glabra L.

open access: yes, 2021
Glycyrrhiza glabra (Licorice) belongs to the Fabaceae family and its extracts have exhibited significant fungicidal activity against phytopathogenic fungi, which has mainly been attributed to the presence of phenolic compounds such as flavonoids ...
Yanping Shi   +4 more
core   +1 more source

Amoebicidal action of isoliquiritigenin and glabridin from Glycyrrhiza species: Mechanisms and effects against Acanthamoeba castellanii.

open access: yesPhytomedicine
BACKGROUND Acanthamoeba is a widely distributed genus, causing keratitis, granulomatous amoebic encephalitis and chronic infectious ulcers. At present, there are no effective drugs available for treating Acanthamoeba infections, highlighting the urgent ...
Lijun Chen   +5 more
semanticscholar   +1 more source

Absolute configuration of naturally occurring glabridin

open access: yes, 2016
The title compound {systematic name: 4-[(3R)-8,8-dimethyl-3,4-di­hydro-2H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol, commonly named glabridin}, C20H20O4, is a species-specific biomarker from the roots Glycyrrhiza glabra L. (European licorice, Fabaceae).
Bernard D Santarsiero (7942562)   +3 more
core  

An evaluation of the effects of glabridin and dexamethasone in bleomycin-induced pulmonary fibrosis: The role of BKCa channels

open access: yes, 2023
Pulmonary fibrosis is a refractory entity with a progressive course and no effective therapeutic options. The purpose of this study was to investigate the potential involvement of both glabridin and dexamethasone (Dex) in inflammatory and fibrotic ...
Bakirhan, Elfide Gizem   +3 more
core   +1 more source

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