Results 81 to 90 of about 2,770 (195)

Glabridin Functions as a Quorum Sensing Inhibitor to Inhibit Biofilm Formation and Swarming Motility of Multidrug-Resistant Acinetobacter baumannii

Infection and Drug Resistance, 2023
Hang Lin,1,2 Cui Zhou,1 Kai-Hang Yu,3 Yi-Shuai Lin,1 Ling-Bo Wang,1 Ying Zhang,1 Shi-Xing Liu,1 Wen-Ya Xu,1 Yao Sun,1 Tie-Li Zhou,1 Jian-Ming Cao,4 Jian-Zhong Ye1 1Department of Clinical Laboratory, Key Laboratory of Clinical Laboratory Diagnosis and ...
Lin H, Zhou C, Yu KH, Lin YS, Wang LB, Zhang Y, Liu SX, Xu WY, Sun Y, Zhou TL, Cao JM, Ye JZ   +11 more
doaj  

Additive Effect of a Combination of Artocarpus lakoocha and Glycyrrhiza glabra Extracts on Tyrosinase Inhibition in Melanoma B16 Cells

Pharmaceuticals, 2020
Artocarpus lakoocha (Al) and Glycyrrhiza glabra (Gg) extracts have been reported to show tyrosinase inhibitory activity and melanin pigment reduction.
Tasanee Panichakul, Teerapat Rodboon, Prasit Suwannalert, Chanchai Tripetch, Rittipun Rungruang, Nattaporn Boohuad, Piyawan Youdee   +6 more
doaj   +1 more source

Multi‐Target Mechanisms of Moroccan Aphrodisiac Plants: An Integrative Computational and Phytochemical Investigation

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Moroccan medicinal plants with in silico‐approved aphrodisiac effects provide 94 phytochemicals. Docking against PDE5, AR, ERα, and aromatase gives top scores for lutein (−10.6), baicalein (−9.5), liquiritigenin (−9.2), and procyanidins (−9.7). ADMET filtering passes baicalein and liquiritigenin but excludes lutein and procyanidins. MD simulations (200 
Amal Elrherabi, Oussama Khibech, Mohamed Bouhrim, Abdelouahid Laftouhi, Abdelaaty A. Shahat, Abdullah R. Alanzi, Rashed N. Herqash, Joe Miantezila Basilua, Mohamed Bnouham   +8 more
wiley   +1 more source

Glabridin triggers over-expression of apoptosis inducing factor (AIF) gene in Candida albicans

Current Medical Mycology, 2018
Background and Purpose: Candida albicans is a prevalent human fungal pathogen that can cause a wide spectrum of diseases, from superficial mucosal infections to systemic disorders, in patients with impaired immunity.
Maryam Moazeni, Mohammad Taghi Hedayati, Mojtaba Nabili   +2 more
doaj  

Pharmacokinetics, pharmacodynamics and safety of vutiglabridin after multiple oral administrations in healthy female and obese subjects

British Journal of Clinical Pharmacology, Volume 92, Issue 3, Page 860-868, March 2026.
Aims Vutiglabridin (HSG4112) is a novel drug under clinical development for antiobesity treatment. This study aimed to evaluate the pharmacokinetics (PKs) and safety of vutiglabridin after multiple oral administrations in healthy Korean female and obese subjects and explore short‐term pharmacodynamic (PD) responses.
Sooyoun Lee, Hyun Chul Kim, Young Ran Yoon, In‐Jin Jang, Sang‐Ku Yoo, Kyung‐Sang Yu   +5 more
wiley   +1 more source

Pretreatment with glabridin prevents carrageenan-induced inflammation: The roles for cytokines and oxidative stress production

, 2021
© 2021, Romanian Society for Pharmaceutical Sciences. All rights reserved.Inflammation is a natural response of the body's immune system to various external stimuli, in which the production of cytokines, nitric oxide, malondialdehyde (MDA) and ...
Annaç, Ebru, Parlar, Ali, Arslan, Seyfullah Oktay, Çam, Saliha Ayşenur   +3 more
core   +1 more source

Functional and Organic Foods in Enhancing the Oral and Dental Health and Hygiene—A Comprehensive Review

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Functional and organic foods contain effective and bioactive compositions. Organic foods and foods enriched with phytochemicals provide promising oral health. Functional foods and beverages in the diet can control and treat oral illnesses ABSTRACT Maintaining oral and dental hygiene, it is significantly related to individuals' quality of life as well ...
Elahe Aleebrahim‐Dehkordi, Ahmad Sheibaninia, Abdolah Ghasemi Pirbalouti   +2 more
wiley   +1 more source

Gene Expression, Docking and Machine Learning in Malaria Drug Discovery: A Systematic Review

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Background Malaria remains a significant and worldwide health threat with increasing resistance to current treatments, stimulating the demand for innovative approaches in pursuing drug discovery. This systematic review integrates the progress made from 2014 through 2024 regarding molecular methods like gene expression profiling, molecular docking and ...
Reuben Samson Dangana, Israel Ehizuelen Ebhohimen, Samson Anjikwi Malgwi, Samuel Chima Ugbaja, Moses Okpeku, Harleen Khatra   +5 more
wiley   +1 more source

Cutaneous Photoaging: A Review of Melasma and Nanotechnological Approaches to Its Control

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Skin is a complex tissue that performs important functions to protect the body against environmental stressors and also synthesizes melanin, a pigment essential for preventing keratinocyte DNA from UV‐induced damage. Excessive solar radiation triggers skin photoaging, leading to hyperactivation of melanocytes and the development of melasma on the face.
Daniela Mayra de Oliveira Figueiredo, Mateus Freire Leite, Suraiya Saleem   +2 more
wiley   +1 more source

Chromenopyridine Derivatives as Novel 6PGD Inhibitors, MD Simulation, and Antioxidant Capacities

Journal of Chemistry, Volume 2026, Issue 1, 2026.
This study investigated the inhibitory effects of chromeno[4,3‐b]pyridine‐benzisoxazole derivatives on 6‐phosphogluconate dehydrogenase (6PGD), an important target enzyme in cancer treatment. In vitro analyses determined Ki values of 1.77 μM and 2.21 μM for Compounds 1 and 2, respectively.
Arzu Ozturk Kesebır, Hülya Akıncıoglu, Veysel Comaklı, Munmun Bardhan   +3 more
wiley   +1 more source