Results 1 to 10 of about 262,302 (346)
Radial glia at the neurovascular interface during cortical development [PDF]
Frontiers in Cellular NeuroscienceRadial glia are a specialized population of neural progenitor cells that persist throughout embryogenesis and into adulthood. Throughout this period, radial glia reside in a highly dynamic microenvironment that influences various biological decisions ...
Njoud Al-Naama, Caroline Alayne Pearson
doaj +2 more sources
eLife, 2022 The discovery of meningeal lymphatic vessels that drain the CNS has prompted new insights into how immune responses develop in the brain. In this study, we examined how T cell responses against CNS-derived antigen develop in the context of infection.
Michael A Kovacs +8 more
doaj +1 more source
Cells, 2023 Clinical and pre-clinical studies of neuropsychiatric (NP) disorders show altered astrocyte properties and synaptic networks. These are refined during early postnatal developmental (PND) stages.
Eugenia Vivi +3 more
doaj +1 more source
An open-source tool for automated analysis of breathing behaviors in common marmosets and rodents
eLife, 2022 The respiratory system maintains homeostatic levels of oxygen (O2) and carbon dioxide (CO2) in the body through rapid and efficient regulation of breathing frequency and depth (tidal volume).
Mitchell Bishop +4 more
doaj +1 more source
Evidence for oligodendrocyte progenitor cell heterogeneity in the adult mouse brain
Scientific Reports, 2022 Oligodendrocyte progenitor cells (OPCs) account for approximately 5% of the adult brain and have been historically studied for their role in myelination.
Rebecca M. Beiter +8 more
doaj +1 more source
Nature Communications, 2022 Disruption of the blood brain barrier can occur in several diseases. Here the authors show that targeted ablation of astrocytes results in a plasticity mechanism in nearby cells to maintain cerebrovascular coverage, but that this mechanism is impaired in
William A. Mills +9 more
doaj +1 more source
Stem Cell Research & Therapy, 2013 Twenty years ago glial cells were shown to contribute to neuronal information processing, instead of merely supporting neuronal function, thus challenging the century old neuron doctrine. Due to the lack of appropriate experimental models, however, determining the role of glia in higher brain function and disease has been hampered.
Spitzer, Sonia +2 more
openaire +2 more sources
Current Neuropharmacology, 2010 Glial cells coordinate the differentiation, metabolism, and excitability of neurons; they modulate synaptic transmission and integrate signals emanating from neurons and other glial cells. Several evidences underlying the relation between these pathways and the regulatory mechanisms of ion concentration, supporting the role of Aquaporins (AQPs) in ...
R. Albertini, R. Bianchi
openaire +3 more sources
Peripheral glia diversity [PDF]
Journal of Anatomy, 2021 AbstractRecent years have seen an evolving appreciation for the role of glial cells in the nervous system. As we move away from the typical neurocentric view of neuroscience, the complexity and variability of central nervous system glia is emerging, far beyond the three main subtypes: astrocytes, oligodendrocytes, and microglia.
Reed, Chelsey B +2 more
openaire +2 more sources
Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis
Nature Communications, 2020 Traumatic brain injury (TBI) is a serious and poorly understood medical condition. Here, the authors show that TBI induces long-lasting deficits in brain lymphatic drainage.
Ashley C. Bolte +12 more
doaj +1 more source