Results 21 to 30 of about 160,715 (360)

Regulations of Retinal Inflammation: Focusing on Müller Glia

Frontiers in Cell and Developmental Biology, 2022
Retinal inflammation underlies multiple prevalent retinal diseases. While microglia are one of the most studied cell types regarding retinal inflammation, growing evidence shows that Müller glia play critical roles in the regulation of retinal ...
Yingying Chen, Qinghong Xia, Yue Zeng, Yun Zhang, Meixia Zhang   +4 more
semanticscholar   +1 more source

Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection

Nature Communications, 2020
Control over T. gondii infection in the brain involves microglial cells, but how these cells execute this control is not clear. Here the authors show that unlike IL-1β dominant macrophages, microglia are primed for gasdermin-D-dependent IL-1α production ...
Samantha J. Batista, Katherine M. Still, David Johanson, Jeremy A. Thompson, Carleigh A. OʼBrien, John R. Lukens, Tajie H. Harris   +6 more
doaj   +1 more source

Regenerative neurogenic response from glia requires insulin driven neuron-glia communication [PDF]

, 2021
Understanding how injury to the central nervous system induces de novo neurogenesis in animals would help promote regeneration in humans. Regenerative neurogenesis could originate from glia and glial neuron-glia antigen-2 (NG2) may sense injury-induced ...
Yang, Zidan, Marta Moreira, Losada-Perez, Maria, Alicia Hidalgo, Altenhein, Benjamin, Sun, Jun, Zidan Yang, Moreira, Marta, Neale J Harrison, Hidalgo, Alicia; id_orcid, Hidalgo, Alicia, Elizabeth Connolly, Benjamin Altenhein, Connolly, Elizabeth, Gascón Gunieda, Alicia, Maria Losada Perez, Harrison, Neale, Gubieda, Alicia Gascón, Alicia Gascón Gubieda, Jun Sun, Losada Pérez, María De La Paloma   +20 more
core   +1 more source

Development of myelinating glia: an overview

Glia, 2022
Myelin is essential to nervous system function, playing roles in saltatory conduction and trophic support. Oligodendrocytes (OLs) and Schwann cells (SCs) form myelin in the central and peripheral nervous systems respectively and follow different ...
Carlo D. D. Cristobal, Hyun Kyoung Lee
semanticscholar   +1 more source

Protocol to downregulate GABAergic-astrocyte signaling via astrocyte-selective ablation of GABAB receptor in adult mice

STAR Protocols, 2022
Summary: Here, we present a protocol to selectively downregulate GABAB receptor (GABABR) expression in astrocytes of mouse medial prefrontal cortex (mPFC). We first describe the procedure of surgeries and viral injections.
Sara Mederos, Andrea Sánchez-Ruiz, Gertrudis Perea   +2 more
doaj   +1 more source

Radial glia and radial glia-like cells: Their role in neurogenesis and regeneration

Frontiers in Neuroscience, 2022
Radial glia is a cell type traditionally associated with the developing nervous system, particularly with the formation of cortical layers in the mammalian brain.
Y. Miranda-Negrón, J. García-Arrarás
semanticscholar   +1 more source

Characterizing circulating tumor cells using affinity-based microfluidic capture and AFM-based biomechanics

STAR Protocols, 2022
Summary: Elasticity and bio-adhesiveness of circulating tumor cells (CTCs) are important biomarkers of cancer. CTCs are rare in blood, thus their capture and atomic force microscopy (AFM)-based biomechanical characterization require use of ...
Muhammedin Deliorman, Ayoub Glia, Mohammad A. Qasaimeh   +2 more
doaj   +1 more source

Effects of glutamate receptor activation on NG2-glia in the rat optic nerve [PDF]

, 2009
NG2-glia are a substantial population of cells in the central nervous system (CNS) that can be identified by their specific expression of the NG2 chondroitin sulphate (CSPG).
Hubbard, Paul S., Hamilton, Nicola; id_orcid, Hamilton, N., Butt, Arthur, Hubbard, Paul, Butt, Arthur M., Hamilton, N, Hubbard, P., Butt, AM   +8 more
core   +1 more source

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

Journal of Neuroscience, 2014
The major cell classes of the brain differ in their developmental processes, metabolism, signaling, and function. To better understand the functions and interactions of the cell types that comprise these classes, we acutely purified representative ...
Ye Zhang, Kenian Chen, S. Sloan, Mariko L. Bennett, A. Scholze, S. O’Keeffe, Hemali P. Phatnani, P. Guarnieri, Christine Caneda, N. Ruderisch, Shuyun Deng, S. A. Liddelow, Chaolin Zhang, R. Daneman, T. Maniatis, B. Barres, Jian Wu   +16 more
semanticscholar   +1 more source

No Longer Underappreciated: The Emerging Concept of Astrocyte Heterogeneity in Neuroscience

Brain Sciences, 2020
Astrocytes are ubiquitous in the central nervous system (CNS). These cells possess thousands of individual processes, which extend out into the neuropil, interacting with neurons, other glia and blood vessels.
Francisco Pestana, Gabriela Edwards-Faret, T. Grant Belgard, Araks Martirosyan, Matthew G. Holt   +4 more
doaj   +1 more source