Results 11 to 20 of about 263,899 (349)

Ferroptosis in Parkinson's disease: glia-neuron crosstalk.

open access: yesTrends in Molecular Medicine, 2022
Parkinson's disease (PD) is characterized by dopaminergic (DA) neuron loss and the formation of cytoplasmic protein inclusions. Although the exact pathogenesis of PD is unknown, iron dyshomeostasis has been proposed as a potential contributing factor ...
Zhang-Li Wang   +3 more
semanticscholar   +1 more source

The “Neuro-Glial-Vascular” Unit: The Role of Glia in Neurovascular Unit Formation and Dysfunction

open access: yesFrontiers in Cell and Developmental Biology, 2021
The neurovascular unit (NVU) is a complex multi-cellular structure consisting of endothelial cells (ECs), neurons, glia, smooth muscle cells (SMCs), and pericytes.
E. Kugler, J. Greenwood, R. MacDonald
semanticscholar   +1 more source

Clever glia [PDF]

open access: yesStem Cell Research & Therapy, 2013
Twenty years ago glial cells were shown to contribute to neuronal information processing, instead of merely supporting neuronal function, thus challenging the century old neuron doctrine. Due to the lack of appropriate experimental models, however, determining the role of glia in higher brain function and disease has been hampered.
Spitzer, Sonia   +2 more
openaire   +2 more sources

Aquaporins and Glia [PDF]

open access: yesCurrent Neuropharmacology, 2010
Glial cells coordinate the differentiation, metabolism, and excitability of neurons; they modulate synaptic transmission and integrate signals emanating from neurons and other glial cells. Several evidences underlying the relation between these pathways and the regulatory mechanisms of ion concentration, supporting the role of Aquaporins (AQPs) in ...
R. Albertini, R. Bianchi
openaire   +3 more sources

Peripheral glia diversity [PDF]

open access: yesJournal of Anatomy, 2021
AbstractRecent years have seen an evolving appreciation for the role of glial cells in the nervous system. As we move away from the typical neurocentric view of neuroscience, the complexity and variability of central nervous system glia is emerging, far beyond the three main subtypes: astrocytes, oligodendrocytes, and microglia.
Reed, Chelsey B   +2 more
openaire   +2 more sources

Development of myelinating glia: An overview

open access: yesGlia, 2022
Myelin is essential to nervous system function, playing roles in saltatory conduction and trophic support. Oligodendrocytes (OLs) and Schwann cells (SCs) form myelin in the central and peripheral nervous systems respectively and follow different ...
Carlo D. D. Cristobal, Hyun Kyoung Lee
semanticscholar   +1 more source

Regulations of Retinal Inflammation: Focusing on Müller Glia

open access: yesFrontiers in Cell and Developmental Biology, 2022
Retinal inflammation underlies multiple prevalent retinal diseases. While microglia are one of the most studied cell types regarding retinal inflammation, growing evidence shows that Müller glia play critical roles in the regulation of retinal ...
Yingying Chen   +4 more
semanticscholar   +1 more source

Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia

open access: yesNature Neuroscience, 2020
The human cortex comprises diverse cell types that emerge from an initially uniform neuroepithelium that gives rise to radial glia, the neural stem cells of the cortex.
Ugomma C. Eze   +4 more
semanticscholar   +1 more source

Diversity of satellite glia in sympathetic and sensory ganglia

open access: yesbioRxiv, 2021
Satellite glia are the major glial type found in ganglia of the peripheral nervous system and wrap around cell bodies of sympathetic and sensory neurons that are very diverse. Other than their close physical association with peripheral neurons, little is
Aurelia A Mapps   +5 more
semanticscholar   +1 more source

Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection

open access: yesNature Communications, 2020
Control over T. gondii infection in the brain involves microglial cells, but how these cells execute this control is not clear. Here the authors show that unlike IL-1β dominant macrophages, microglia are primed for gasdermin-D-dependent IL-1α production ...
Samantha J. Batista   +6 more
doaj   +1 more source

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