Results 11 to 20 of about 102,413 (266)

Enteric glia: the most alimentary of all glia [PDF]

open access: yesThe Journal of Physiology, 2016
AbstractGlia (from Greek γλοία meaning ‘glue’) pertains to non‐neuronal cells in the central (CNS) and peripheral nervous system (PNS) that nourish neurons and maintain homeostasis. In addition, glia are now increasingly appreciated as active regulators of numerous physiological processes initially considered exclusively under neuronal regulation.
Vladimir Grubišić, Brian D. Gulbransen
openaire   +2 more sources

Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection

open access: yesNature Communications, 2020
Control over T. gondii infection in the brain involves microglial cells, but how these cells execute this control is not clear. Here the authors show that unlike IL-1β dominant macrophages, microglia are primed for gasdermin-D-dependent IL-1α production ...
Samantha J. Batista   +6 more
doaj   +1 more source

Protocol to downregulate GABAergic-astrocyte signaling via astrocyte-selective ablation of GABAB receptor in adult mice

open access: yesSTAR Protocols, 2022
Summary: Here, we present a protocol to selectively downregulate GABAB receptor (GABABR) expression in astrocytes of mouse medial prefrontal cortex (mPFC). We first describe the procedure of surgeries and viral injections.
Sara Mederos   +2 more
doaj   +1 more source

Characterizing circulating tumor cells using affinity-based microfluidic capture and AFM-based biomechanics

open access: yesSTAR Protocols, 2022
Summary: Elasticity and bio-adhesiveness of circulating tumor cells (CTCs) are important biomarkers of cancer. CTCs are rare in blood, thus their capture and atomic force microscopy (AFM)-based biomechanical characterization require use of ...
Muhammedin Deliorman   +2 more
doaj   +1 more source

No Longer Underappreciated: The Emerging Concept of Astrocyte Heterogeneity in Neuroscience

open access: yesBrain Sciences, 2020
Astrocytes are ubiquitous in the central nervous system (CNS). These cells possess thousands of individual processes, which extend out into the neuropil, interacting with neurons, other glia and blood vessels.
Francisco Pestana   +4 more
doaj   +1 more source

Dynamic resources of the Sanità spring at Caposele (South Italy)

open access: yesAcque Sotterranee, 2014
The Sanità Spring at Caposele (NE of Campania – South Italy) is the main spring of the Sele river. Since the end of ‘800, it was indicated and was prospected as the possible base of the Acquedotto Pugliese for drinking the dry Apulia zone. The spring was
Massimo V. Civita, Katia Rostagno
doaj   +1 more source

Identification of region-specific astrocyte subtypes at single cell resolution

open access: yesNature Communications, 2020
Astrocytes are a major cell type in the central nervous system. Using single cell transcriptome sequencing, the authors identify multiple astrocyte subtypes in the adult mouse CNS, which map to distinct spatial locations and show correlations to cell ...
Mykhailo Y. Batiuk   +12 more
doaj   +1 more source

Peripheral glia diversity [PDF]

open access: yesJournal of Anatomy, 2021
AbstractRecent years have seen an evolving appreciation for the role of glial cells in the nervous system. As we move away from the typical neurocentric view of neuroscience, the complexity and variability of central nervous system glia is emerging, far beyond the three main subtypes: astrocytes, oligodendrocytes, and microglia.
Reed, Chelsey B   +2 more
openaire   +2 more sources

Perineurial Glia [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2015
Although the ultrastructure of peripheral nerves has been known for nearly 200 years, the developmental origins and functional roles of all five main components of these specialized nervous system conduits are still poorly understood. One of these understudied nerve elements, the perineurium, is a component of the blood-nerve barrier and is essential ...
openaire   +2 more sources

Stroke propensity in the Th3+/ mouse model of β-thalassemia intermedia

open access: yesNeurobiology of Disease, 2022
β-thalassemia is associated with multiple hematological and cerebrovascular symptoms linked to a hypercoagulable state that has not been fully replicated in animal models for the development of stroke treatments.
Yu-Yo Sun   +5 more
doaj   +1 more source

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