Results 11 to 20 of about 131,815 (313)

Peripheral glia diversity [PDF]

open access: yesJournal of Anatomy, 2021
AbstractRecent years have seen an evolving appreciation for the role of glial cells in the nervous system. As we move away from the typical neurocentric view of neuroscience, the complexity and variability of central nervous system glia is emerging, far beyond the three main subtypes: astrocytes, oligodendrocytes, and microglia.
Reed, Chelsey B   +2 more
openaire   +3 more sources

Drosophila ClC-a is required in glia of the stem cell niche for proper neurogenesis and wiring of neural circuits [PDF]

open access: yes, 2021
Glial cells form part of the neural stem cell niche and express a wide variety of ion channels; however, the contribution of these channels to nervous system develop ment is poorly understood.
Rios, Martín   +5 more
core   +1 more source

Enteric glia: the most alimentary of all glia [PDF]

open access: yesThe Journal of Physiology, 2016
AbstractGlia (from Greek γλοία meaning ‘glue’) pertains to non‐neuronal cells in the central (CNS) and peripheral nervous system (PNS) that nourish neurons and maintain homeostasis. In addition, glia are now increasingly appreciated as active regulators of numerous physiological processes initially considered exclusively under neuronal regulation.
Vladimir Grubišić, Brian D. Gulbransen
openaire   +2 more sources

Regenerative neurogenic response from glia requires insulin driven neuron-glia communication [PDF]

open access: yes, 2021
Understanding how injury to the central nervous system induces de novo neurogenesis in animals would help promote regeneration in humans. Regenerative neurogenesis could originate from glia and glial neuron-glia antigen-2 (NG2) may sense injury-induced ...
Yang, Zidan   +20 more
core   +1 more source

Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection

open access: yesNature Communications, 2020
Control over T. gondii infection in the brain involves microglial cells, but how these cells execute this control is not clear. Here the authors show that unlike IL-1β dominant macrophages, microglia are primed for gasdermin-D-dependent IL-1α production ...
Samantha J. Batista   +6 more
doaj   +1 more source

Protocol to downregulate GABAergic-astrocyte signaling via astrocyte-selective ablation of GABAB receptor in adult mice

open access: yesSTAR Protocols, 2022
Summary: Here, we present a protocol to selectively downregulate GABAB receptor (GABABR) expression in astrocytes of mouse medial prefrontal cortex (mPFC). We first describe the procedure of surgeries and viral injections.
Sara Mederos   +2 more
doaj   +1 more source

Characterizing circulating tumor cells using affinity-based microfluidic capture and AFM-based biomechanics

open access: yesSTAR Protocols, 2022
Summary: Elasticity and bio-adhesiveness of circulating tumor cells (CTCs) are important biomarkers of cancer. CTCs are rare in blood, thus their capture and atomic force microscopy (AFM)-based biomechanical characterization require use of ...
Muhammedin Deliorman   +2 more
doaj   +1 more source

Effects of glutamate receptor activation on NG2-glia in the rat optic nerve [PDF]

open access: yes, 2009
NG2-glia are a substantial population of cells in the central nervous system (CNS) that can be identified by their specific expression of the NG2 chondroitin sulphate (CSPG).
Hubbard, Paul S.   +8 more
core   +1 more source

No Longer Underappreciated: The Emerging Concept of Astrocyte Heterogeneity in Neuroscience

open access: yesBrain Sciences, 2020
Astrocytes are ubiquitous in the central nervous system (CNS). These cells possess thousands of individual processes, which extend out into the neuropil, interacting with neurons, other glia and blood vessels.
Francisco Pestana   +4 more
doaj   +1 more source

Morphological and physiological interactions of NG2-glia with astrocytes and neurons [PDF]

open access: yes, 2007
Models of central nervous system (CNS) function have historically been based on neurons and their synaptic contacts - the neuronal doctrine. This doctrine envisages glia as passive supportive cells.
Hamilton, N.   +12 more
core   +1 more source

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