Results 31 to 40 of about 131,815 (313)

Exosomes from NSC-34 Cells Transfected with hSOD1-G93A Are Enriched in miR-124 and Drive Alterations in Microglia Phenotype

open access: yesFrontiers in Neuroscience, 2017
Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neurodegenerative disorder affecting motor neurons (MNs). Evidences indicate that ALS is a non-cell autonomous disease in which glial cells participate in both disease onset and progression ...
Sara Pinto   +6 more
doaj   +1 more source

Morpho-Functional Consequences of Swiss Cheese Knockdown in Glia of Drosophila melanogaster

open access: yesCells, 2021
Glia are crucial for the normal development and functioning of the nervous system in many animals. Insects are widely used for studies of glia genetics and physiology.
Elena V. Ryabova   +7 more
doaj   +1 more source

The Blood-Brain Barrier and the EphR/Ephrin System: Perspectives on a Link Between Neurovascular and Neuropsychiatric Disorders

open access: yesFrontiers in Molecular Neuroscience, 2018
Interactions among endothelial cells (EC) forming blood vessels and their surrounding cell types are essential to establish the blood-brain barrier (BBB), an integral part of the neurovascular unit (NVU).
Victoria A. Malik   +2 more
doaj   +1 more source

Age-dependent remodelling of ionotropic signalling in cortical astroglia [PDF]

open access: yes, 2011
Cortical astrocytes express fast ionotropic receptors for glutamate and ATP, although their role in neurone-glia communication remains controversial.
Lalo, Ulyana   +11 more
core   +1 more source

Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration

open access: yesEMBO Molecular Medicine, 2015
Retinitis pigmentosa, caused predominantly by mutations in photoreceptor genes, currently lacks comprehensive treatment. We discover that retinal microglia contribute non‐cell autonomously to rod photoreceptor degeneration by primary phagocytosis of ...
Lian Zhao   +9 more
doaj   +1 more source

Astrocytes, Noradrenaline, α1-Adrenoreceptors, and Neuromodulation: Evidence and Unanswered Questions

open access: yesFrontiers in Cellular Neuroscience, 2021
Noradrenaline is a major neuromodulator in the central nervous system (CNS). It is released from varicosities on neuronal efferents, which originate principally from the main noradrenergic nuclei of the brain – the locus coeruleus – and spread throughout
Jérôme Wahis   +5 more
doaj   +1 more source

Glia-specific AMP knockdown does not affect post-TBI mortality.

open access: yes, 2022
Kaplan–Meier plots for glia-specific RNAi-mediated knockdown of AMPs. Repo>RNAi lines are compared to Repo>RNAi control lines using a log-rank test. n.s. = not significant.
Anujaianthi Ramakrishnan (12003733)   +11 more
core   +1 more source

Satellite glia modulate sympathetic neuron survival, activity, and autonomic function

open access: yeseLife, 2022
Satellite glia are the major glial cells in sympathetic ganglia, enveloping neuronal cell bodies. Despite this intimate association, the extent to which sympathetic functions are influenced by satellite glia in vivo remains unclear.
Aurelia A Mapps   +10 more
doaj   +1 more source

NG2 glia are required for maintaining microglia homeostatic state [PDF]

open access: yes, 2019
Microglia play vital roles in the health and diseases of the central nervous system. Loss of microglia homeostatic state is a key feature of brain aging and neurodegeneration.
Liu, Yingjun; https://orcid.org/   +1 more
core   +1 more source

Glia-induced neuronal differentiation by transcriptional regulation.

open access: yes, 2007
There is increasing evidence that different phases of brain development depend on neuron-glia interactions including postnatal key events like synaptogenesis.
Schurgers, Leon J   +13 more
core   +1 more source

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