Results 31 to 40 of about 263,899 (349)
Identification of region-specific astrocyte subtypes at single cell resolution
Nature Communications, 2020 Astrocytes are a major cell type in the central nervous system. Using single cell transcriptome sequencing, the authors identify multiple astrocyte subtypes in the adult mouse CNS, which map to distinct spatial locations and show correlations to cell ...
Mykhailo Y. Batiuk +12 more
doaj +1 more source
Celiac Immunogenic Potential of α-Gliadin Epitope Variants from Triticum and Aegilops Species [PDF]
, 2019 The high global demand of wheat and its subsequent consumption arise from the physicochemical properties of bread dough and its contribution to the protein intake in the human diet.
Barro Losada, Francisco +8 more
core +1 more source
Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum. [PDF]
, 2013 NG2 (nerve/glial antigen2)-expressing cells represent the largest population of postnatal progenitors in the central nervous system and have been classified as oligodendroglial progenitor cells, but the fate and function of these cells remain ...
Chung, S-H +4 more
core +2 more sources
The glia response after peripheral nerve injury: A comparison between Schwann cells and olfactory ensheathing cells and their uses for neural regenerative therapies [PDF]
, 2017 The peripheral nervous system (PNS) exhibits a much larger capacity for regeneration than the central nervous system (CNS). One reason for this difference is the difference in glial cell types between the two systems.
Barton, Matthew J. +4 more
core +2 more sources
NG2 glia-derived GABA release tunes inhibitory synapses and contributes to stress-induced anxiety
Nature Communications, 2021 NG2 glia, also known as oligodendrocyte precursor cells (OPCs), play an important role in proliferation and give rise to myelinating oligodendrocytes during early brain development. In contrast to other glial cell types, the most intriguing aspect of NG2
Xiao Zhang +13 more
semanticscholar +1 more source
Cold Spring Harbor Perspectives in Biology, 2015 Although the ultrastructure of peripheral nerves has been known for nearly 200 years, the developmental origins and functional roles of all five main components of these specialized nervous system conduits are still poorly understood. One of these understudied nerve elements, the perineurium, is a component of the blood-nerve barrier and is essential ...
openaire +2 more sources
Reactive Glia Inflammatory Signaling Pathways and Epilepsy
International Journal of Molecular Sciences, 2020 Neuroinflammation and epilepsy are interconnected. Brain inflammation promotes neuronal hyper-excitability and seizures, and dysregulation in the glia immune-inflammatory function is a common factor that predisposes or contributes to the generation of ...
P. Sanz, M. García-Gimeno
semanticscholar +1 more source
Defective phagocytic corpse processing results in neurodegeneration and can be rescued by TORC1 activation [PDF]
, 2016 This work was supported by NIH Grants R01 GM094452 (K.M.) and F31 GM099425 (J.I.E.), BU Alzheimer's Disease Core Center NIH Grant P30 AG13846, Boston University Undergraduate Research Opportunities Program grants (J.A.T., V.S.), and NIH Grant R01 ...
Elguero, Emma J. +5 more
core +1 more source
Science Translational Medicine, 2021 Description TLR4-induced enteric glia loss leads to experimental NEC through BDNF loss, which can be treated with by compound J11. NEC takes its Toll Toll-like receptor-4 (TLR4) has been implicated in the pathophysiology of necrotizing enterocolitis (NEC)
M. Kovler +13 more
semanticscholar +1 more source
Stroke propensity in the Th3+/ mouse model of β-thalassemia intermedia
Neurobiology of Disease, 2022 β-thalassemia is associated with multiple hematological and cerebrovascular symptoms linked to a hypercoagulable state that has not been fully replicated in animal models for the development of stroke treatments.
Yu-Yo Sun +5 more
doaj +1 more source