Results 31 to 40 of about 262,302 (346)

NG2 glia-derived GABA release tunes inhibitory synapses and contributes to stress-induced anxiety

Nature Communications, 2021
NG2 glia, also known as oligodendrocyte precursor cells (OPCs), play an important role in proliferation and give rise to myelinating oligodendrocytes during early brain development. In contrast to other glial cell types, the most intriguing aspect of NG2
Xiao Zhang, Yao Liu, Xiaoqi Hong, Xia Li, C. Meshul, C. Moore, Yabing Yang, Yanfei Han, Wei-Guang Li, Xin Qi, Huifang Lou, S. Duan, Tian-Le Xu, Xiaoping Tong   +13 more
semanticscholar   +1 more source

Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum. [PDF]

, 2013
NG2 (nerve/glial antigen2)-expressing cells represent the largest population of postnatal progenitors in the central nervous system and have been classified as oligodendroglial progenitor cells, but the fate and function of these cells remain ...
Chung, S-H, Deng, W, Guo, F, Jiang, P, Pleasure, DE   +4 more
core   +2 more sources

HIV-1 Tat exacerbates lipopolysaccharide-induced cytokine release via TLR4 signaling in the enteric nervous system [PDF]

, 2016
The loss of gut epithelium integrity leads to translocation of microbes and microbial products resulting in immune activation and drives systemic inflammation in acquired immunodeficiency syndrome (AIDS) patients. Although viral loads in HIV patients are
Akbarali, Hamid I., Bhave, Sukhada, Brun, Paola, Dewey, William L., Fitting, Sylvia, Guedia, Joy, Hauser, Kurt F., Kang, Minho   +7 more
core   +1 more source

Toll-like receptor 4–mediated enteric glia loss is critical for the development of necrotizing enterocolitis

Science Translational Medicine, 2021
Description TLR4-induced enteric glia loss leads to experimental NEC through BDNF loss, which can be treated with by compound J11. NEC takes its Toll Toll-like receptor-4 (TLR4) has been implicated in the pathophysiology of necrotizing enterocolitis (NEC)
M. Kovler, Andres J. Gonzalez Salazar, W. Fulton, P. Lu, Yukihiro Yamaguchi, Qinjie Zhou, M. Sampah, Asuka Ishiyama, T. Prindle, Sanxia Wang, H. Jia, P. Wipf, C. Sodhi, D. Hackam   +13 more
semanticscholar   +1 more source

Microglial K(+) channel expression in young adult and aged mice. [PDF]

, 2014
The K(+) channel expression pattern of microglia strongly depends on the cells' microenvironment and has been recognized as a sensitive marker of the cells' functional state. While numerous studies have been performed on microglia in vitro, our knowledge
Eder, C, Schilling, T
core   +1 more source

Perineurial Glia [PDF]

Cold Spring Harbor Perspectives in Biology, 2015
Although the ultrastructure of peripheral nerves has been known for nearly 200 years, the developmental origins and functional roles of all five main components of these specialized nervous system conduits are still poorly understood. One of these understudied nerve elements, the perineurium, is a component of the blood-nerve barrier and is essential ...
openaire   +2 more sources

Neuroinflammation, Mast Cells, and Glia: Dangerous Liaisons [PDF]

, 2017
The perspective of neuroinflammation as an epiphenomenon following neuron damage is being replaced by the awareness of glia and their importance in neural functions and disorders.
Alhouayek M, Amor S, Amor S, Appel SH, Bankston AN, Biber K, Biran V, Borsook D, Brenner T, Brooks TA, Buchanan MM, Bulanova E, Burnstock G, Calcia MA, Castellheim A, Chan-Ling T, Chen YJ, Choudhuri K, Christophi GP, Christy AL, Compston A, Conti P, Corrigan F, Cristino L, Cunningham C, Dirckx M, Donath MY, Done JD, D’Agostino G, Eckenhoff RG, Eggen BJ, Ellis A, Engler H, Ertürk A, Eskander MA, Esposito P, Fonken LK, Forsythe P, Freeman LC, Fullerton JN, Gao YJ, Gaudenzio N, Geppetti P, Grace PM, Grakoui A, Gregory GD, Griffin RS, Guerreiro R, Gunin AG, Hagiyama M, Hains LE, Hanisch UK, Harcha PA, Harvey GK, Hayashi R, Heneka MT, Hickman SE, Hsieh CL, Hu W, Héron A, Iadecola C, Ito A, Jay GW, Jensen TS, Ji RR, Jin Y, Jin Y, Juremalm M, Kajihara Y, Kalesnikoff J, Kalichman MW, Kamm CP, Kerstman E, Kobayashi K, Kolbinger F, Koshinaga M, Kwon C, Lange C, Lapilover EG, Laura Facci, Le Thuc O, Leon A, Levy D, Li M, Li X, Liew FY, Lozada A, Lull ME, Luongo L, Manocha GD, Marchi N, Martini R, Maslinska D, Mate I, Matsuda H, Mattila OS, McGeer PL, Medeiros R, Medic N, Medic N, Michaloudi H, Michaud M, Millan MJ, Miller G, Milligan ED, Monks CR, Morena Zusso, Myers RR, Nakae S, Nakajima A, Nathan C, Nave KA, Nelissen S, Nguyen M, Norden DM, Noriega DB, Old EA, Orr AG, Osipchuk Y, Osterberg A, Park CK, Parvathenani LK, Patti GJ, Peferoen L, Peferoen LA, Pekny M, Pelisch N, Perry VH, Perry VH, Pietro Giusti, Prinz M, Prussin C, Punzo D, Ramlackhansingh AF, Ransohoff RM, Rapp JH, Rawji KS, Riedel B, Rivat C, Rosa AC, Sakamoto A, Sastre M, Sayed BA, Silver R, Silverman AJ, Sivanandam TM, Skaper SD, Skaper SD, Skaper SD, Skaper SD, Skaper SD, Skuljec J, Smith BH, Smith JA, Sospedra M, Stephen D. Skaper, Streit WJ, Suurmond J, Terrando N, Thacker MA, Theoharides TC, Theoharides TC, Theoharides TC, Theoharides TC, Theoharides TC, Ulmann L, van Hecke O, Varma R, von Büdingen HC, Vyas H, Wang M, Wang Y, Wardlaw AJ, Watkins LR, Wohleb ES, Xie F, Young KM, Yuan H, Zarpelon AC, Zeis T, Zhang H, Zhang S, Zhang ZG, Zuo Y   +183 more
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Stroke propensity in the Th3+/ mouse model of β-thalassemia intermedia

Neurobiology of Disease, 2022
β-thalassemia is associated with multiple hematological and cerebrovascular symptoms linked to a hypercoagulable state that has not been fully replicated in animal models for the development of stroke treatments.
Yu-Yo Sun, Hui-Wen Yao, Hong-Ru Chen, Ching-Wen Chen, Melissa M. Kinkaid, Chia-Yi Kuan   +5 more
doaj   +1 more source

Enteric Glia Modulate Macrophage Phenotype and Visceral Sensitivity following Inflammation

Cell Reports, 2020
SUMMARY Mechanisms resulting in abdominal pain include altered neuro-immune interactions in the gastrointestinal tract, but the signaling processes that link immune activation with visceral hypersensitivity are unresolved.
Vladimir Grubišić, Jonathon L. McClain, D. Fried, I. Grants, P. Rajasekhar, E. Csizmadia, O. Ajijola, R. Watson, D. Poole, S. Robson, F. Christofi, Brian D. Gulbransen   +11 more
semanticscholar   +1 more source

Morphological plasticity of astroglia: Understanding synaptic microenvironment [PDF]

, 2015
Memory formation in the brain is thought to rely on the remodeling of synaptic connections which eventually results in neural network rewiring. This remodeling is likely to involve ultrathin astroglial protrusions which often occur in the immediate ...
Heller, JP, Rusakov, DA
core   +1 more source