Results 51 to 60 of about 262,302 (346)
Frontiers in Molecular Neuroscience, 2018 Interactions among endothelial cells (EC) forming blood vessels and their surrounding cell types are essential to establish the blood-brain barrier (BBB), an integral part of the neurovascular unit (NVU).
Victoria A. Malik +2 more
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Frontiers in Cellular Neuroscience, 2021 Noradrenaline is a major neuromodulator in the central nervous system (CNS). It is released from varicosities on neuronal efferents, which originate principally from the main noradrenergic nuclei of the brain – the locus coeruleus – and spread throughout
Jérôme Wahis +5 more
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Reprogramming Müller Glia to Regenerate Retinal Neurons.
Annual Review of Vision Science, 2020 In humans, various genetic defects or age-related diseases, such as diabetic retinopathies, glaucoma, and macular degeneration, cause the death of retinal neurons and profound vision loss.
M. Lahne +3 more
semanticscholar +1 more source
Transient astrocyte‐like NG2 glia subpopulation emerges solely following permanent brain ischemia
Glia, 2021 NG2 glia display wide proliferation and differentiation potential under physiological and pathological conditions. Here, we examined these two features following different types of brain disorders such as focal cerebral ischemia (FCI), cortical stab ...
Denisa Kirdajova +12 more
semanticscholar +1 more source
Brainiac Caspases: Beyond the Wall of Apoptosis [PDF]
, 2019 For the last two decades, caspases, a family of cysteine-aspartic proteases, have evolved from being considered solely as regulators of apoptosis or inflammation to having a wider range of functions.
Alonso Bellido, Isabel María +3 more
core +1 more source
Transient Astrocytic Gq Signaling Underlies Remote Memory Enhancement
Frontiers in Neural Circuits, 2021 Astrocytes elicit transient Ca2+ elevations induced by G protein-coupled receptors (GPCRs), yet their role in vivo remains unknown. To address this, transgenic mice with astrocytic expression of the optogenetic Gq-type GPCR, Optoα1AR, were established ...
Youichi Iwai +12 more
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Neuron, 2007 Whether CNS glial cells play an important role in the regulation of complex behaviors has been a longstanding question. In this issue of Neuron, Suh and Jackson demonstrate a circadian rhythmicity in glial expression of ebony, an N-beta-alanyl-biogenic amine synthase, and show that Ebony activity in glia is essential for the proper regulation of ...
Emery, Patrick, Freeman, Marc R.
openaire +3 more sources
A neuron–glia lipid metabolic cycle couples daily sleep to mitochondrial homeostasis
Nature NeuroscienceSleep is thought to be restorative to brain energy homeostasis, but it is not clear how this is achieved. We show here that Drosophila glia exhibit a daily cycle of glial mitochondrial oxidation and lipid accumulation that is dependent on prior wake and ...
Paula Haynes +7 more
semanticscholar +1 more source
Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration
EMBO Molecular Medicine, 2015 Retinitis pigmentosa, caused predominantly by mutations in photoreceptor genes, currently lacks comprehensive treatment. We discover that retinal microglia contribute non‐cell autonomously to rod photoreceptor degeneration by primary phagocytosis of ...
Lian Zhao +9 more
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Enteric glia: the most alimentary of all glia [PDF]
The Journal of Physiology, 2016 AbstractGlia (from Greek γλοία meaning ‘glue’) pertains to non‐neuronal cells in the central (CNS) and peripheral nervous system (PNS) that nourish neurons and maintain homeostasis. In addition, glia are now increasingly appreciated as active regulators of numerous physiological processes initially considered exclusively under neuronal regulation.
Vladimir Grubišić, Brian D. Gulbransen
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