Results 191 to 200 of about 22,955 (239)

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Partners in plasticity: serotonergic glial interactions in brain circuit remodeling. [PDF]

Front Neurosci
Miller VK, Broadie K.
europepmc   +1 more source

Retinal Astrocytes: Key Coordinators of Developmental Angiogenesis and Neurovascular Homeostasis in Health and Disease. [PDF]

Biology (Basel)
Zhang YY, Sun QF, Bai W, Yao J.
europepmc   +1 more source

Special characteristics of human astrocytes and their roles in brain homeostasis. [PDF]

Neurosci Appl
Kousa I, Talvio K, Peteri UK, Castrén ML.   +3 more
europepmc   +1 more source

RXR Gamma Enables Oligodendrocyte Differentiation by Suppressing Sonic Hedgehog Signaling. [PDF]

Glia
Baldassarro VA, Brassart Q, Fraulob V, Calzà L, Krezel W.   +4 more
europepmc   +1 more source

Direct reprogramming of Müller glia into photoreceptors via multiple transcription factors and small molecules: molecular mechanisms and transcriptomic analysis. [PDF]

In Vitro Cell Dev Biol Anim
Endo Y, Sugano E, Seko Y, Fukuda T, Tabata K, Kakizaki T, Maruoka S, Yokoyama T, Mori H, Ozaki T, Bai L, Tomita H.   +11 more
europepmc   +1 more source

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Multiple molecular forms of Glia maturation factor

Biochimica Et Biophysica Acta (BBA) - Protein Structure, 1979
Glia maturation factor from the pig brain can be detected in two molecular forms: the high molecular weight form which is 200 000 dalton in size and the low molecular weight form which is 40 000 dalton in size, as determined by Sephadex gel filtration. The former accounts for 85% of the total biological activity extracted at physiologic pH.
Taiji Kato, D E Turriff, Ramon Lim
exaly   +3 more sources

Sequential interaction of glia maturation factor with insulin

Science, 1984
Astroblasts in culture proliferated when exposed to glia maturation factor for at least 2 hours and then to insulin, but not when exposed in the reverse order. The sequential relation suggests that glia maturation factor is a competence factor.
Ramon Lim
exaly   +3 more sources

Polyclonal antibody localizes glia maturation factor β-like immunoreactivity in neurons and glia

Brain Research, 1992
A rabbit polyclonal antibody (91-01) was raised against recombinant human glia maturation factor beta (r-hGMF-beta). The antibody did not cross-react with a number of other growth factors on ELISA test. When compared with the monoclonal antibody G2-09 previously obtained, 91-01 immunoblotted the same protein band in rat brain extract.
Asgar Zaheer, Ramon Lim
exaly   +3 more sources

Glia maturation factor in bovine brain: Partial purification and physicochemical characterization

Brain Research, 1981
Glia maturation factor (GMF) is partially purified from bovine brains by the following procedure: extraction at physiologic pH, dialysis and freeze-drying of the extract, ethanol washing of the dried powder and re-extraction of the ethanol-washed residue with Tris-buffered saline, ion-exchange chromatography with DEAE Sephadex and molecular sieving ...
Barry G W Árnason, Taiji Kato, B G Árnason   +2 more
exaly   +3 more sources