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Expression of glia maturation factor during retinal development in the rat
Molecular Brain Research, 2001Glia maturation factor plays important roles in the development and growth of glia and neurons. We investigated the expression and localization of Glia maturation factor-beta (GMFB) and Glia maturation factor-gamma (GMFG) in the rat retina. By northern blot analysis, both GMFB and GMFG mRNAs were detected in retina as early as embryonic day (E) 18 and ...
A, Nishiwaki +6 more
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Distribution of Glia Maturation Factor-Like Activity in Organs and Cells
Developmental Neuroscience, 2007Glia maturation factor (GMF) is a protein first isolated from the adult pig brain. GMF-like activity can be demonstrated in rat organs, including brain, kidney and heart. The activity in these organs is low in newborn animals, but increases with development, reaching the adult level in 1 or 2 weeks. GMF-like activities in the various organs are similar
D E, Turriff, R, Lim
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Phorbol Ester Stimulates Rapid Intracellular Phosphorylation of Glia Maturation Factor
Biochemical and Biophysical Research Communications, 1995We report that recombinant glia maturation factor (GMF), a 17-kD brain protein, can be phosphorylated in vitro at the serine residue by protein kinase C (PKC), protein kinase A (PKA), and casein kinase II (CKII), and at the threonine residue by p90 ribosomal S6 kinase (RSK).
R, Lim, A, Zaheer
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Cytoskeletal regulation of normal rat glioblasts differentiated by glia maturation factor
Neurochemistry International, 1990The morphological differentiation of normal rat glioblasts induced by glia maturation factor (GMF) was investigated with regard to the reorganization of the cytoskeletal structures by the use of indirect immunofluorescence staining methods. The microfilaments were reorganized from a stress fiber form to a plasmalemmal undercoat structure by GMF, and to
J, Ito, T, Kato, R, Tanaka
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Expression of glia maturation factor beta after cryogenic brain injury
Molecular Brain Research, 2005Glia maturation factor beta (GMFB) was identified as a growth and differentiation factor acting on neurons as well as glia. We investigated the expression of GMFB during 56 days after cryogenic brain injury, using immunohistochemistry, reverse transcriptase polymerase chain reaction (RT-PCR), Western blotting and enzyme immunoassay. Immunohistochemical
Naokazu, Hotta +6 more
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Biological effects of bovine glia maturation factor on glial cells in culture
Neurochemical Research, 1981Optimal bioassay conditions for bovine glia maturation factor (GMF) were determined among glial cells from normal glioblasts to glioma cells. Rat glioblasts 4-8 days after subculture show the highest response t GMF with regard to morphological transformation and mitogenic activity.
T, Kato +4 more
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Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 2001
Glia maturation factor-beta (GMFB) is a 17-kDa protein that was initially identified as a growth and differentiation factor acting on neurons as well as glia in the vertebrate brain. We isolated human and rat glia maturation factor-gamma (GMFG) cDNA and examined the tissue distribution of GMFG in human and rat by Northern blots and Western blots ...
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Glia maturation factor-beta (GMFB) is a 17-kDa protein that was initially identified as a growth and differentiation factor acting on neurons as well as glia in the vertebrate brain. We isolated human and rat glia maturation factor-gamma (GMFG) cDNA and examined the tissue distribution of GMFG in human and rat by Northern blots and Western blots ...
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Mitogenic activity of glia maturation factor
Experimental Cell Research, 1985Ramon Lim +4 more
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Glia maturation factor increases cyclic GMP in glioblasts
Brain Research, 1979D E, Turriff, R, Lim
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