Comparison of glycemic excursion in patients with new onset type 2 diabetes mellitus before and after treatment with repaglinide [PDF]
, 2013 Due to industrialization and sedentary life, incidence of type 2 diabetes (DM2) is increasing seriously. Repaglinide is a glucose reducing agent that predominantly reduces post-prandial glucose.
Bonakdaran, S. +4 more
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Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 953-963, April 2026.Grapefruit juice is a well‐established inhibitor of cytochrome P450 (CYP) 3A4, but its effects on other CYP enzymes or organic anion transporting polypeptides (OATPs) are not fully characterized in humans. Recently, lingonberry powder was shown to induce murine CYP enzymes. We investigated the effects of lingonberry powder and grapefruit juice on seven
Laura Aurinsalo +7 more
wiley +1 more source
International Journal of Biological Sciences, 2011 Diabetes mellitus is associated with deterioration of glycemic control and progressive metabolic derangements. This study investigated the effect of honey as an adjunct to glibenclamide or metformin on glycemic control in streptozotocin-induced diabetic ...
Omotayo Owomofoyon Erejuwa, Siti Amrah Sulaiman, Mohd Suhaimi Ab Wahab, Kuttulebbai Nainamohammed Salam Sirajudeen, Md Salzihan Md Salleh, Sunil Gurtu
doaj
Cellulose Derivative-Based Bioadhesive Blend Patch for Transdermal Drug Delivery
Frontiers in Materials, 2022 In this study, matrix-type transdermal patches of glibenclamide were developed using a combination of hydrophilic and hydrophobic polymers for investigating the efficacy of transdermal carriers. A cellulose derivative, HPMC E50, was used as a hydrophilic
Sreejan Manna +4 more
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[6]-Gingerol, from Zingiber officinale, potentiates GLP-1 mediated glucose-stimulated insulin secretion pathway in pancreatic β-cells and increases RAB8/RAB10-regulated membrane presentation of GLUT4 transporters in skeletal muscle to improve hyperglycemia in Leprdb/db type 2 diabetic mice [PDF]
, 2017 This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give ...
Akhter, Farjana +9 more
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Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.Graphical abstract illustrating the pharmacological potential of E. spinosa. ABSTRACT Emex spinosa (L.) Campd. (E. spinosa) is a plant species belonging to the Polygonaceae family. It is native to the Middle East, North Africa, and Europe and is most commonly seen on the coastlines of Mediterranean countries.
Smail Amtaghri +9 more
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Comparative Study of Palm Leaves Extract and Glibenclamide in diabetic female rats induced by alloxan [PDF]
Mirror of Research in Veterinary Sciences and Animals, 2013 This study was designed to compare the effect of palm leaves extract and glibenclamide in diabetic female rats induced by alloxan. Twenty four adult female rats were randomly divided into four equal groups (6 rats in each group), three groups were ...
Nabeel M. N. Al-Sharafi Nadia K. J. Al-Dawah +1 more
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Implications of Genetic Elements on Type 2 Diabetes Mellitus Pathogenesis and Management
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 2, March 2026.Genetic variations in T2DM, including key metabolic and insulin‐related genes, influence disease risk, insulin resistance, and drug response. Understanding these polymorphisms enables precision medicine, optimising therapy and improving glycaemic control across diverse populations.
Nokwanda N. Ngcobo, Ntethelelo H. Sibiya
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Stimulation of glucose utilization in 3T3 adipocytes and rat diaphragm in vitro by the sulphonylureas, glimepiride and glibenclamide, is correlated with modulations of the cAMP regulatory cascade [PDF]
, 1994 The long-term hypoglycemic activity of sulphonylurea drugs has been attributed, in part at least, to the stimulation of glucose utilization in extra-pancreatic tissues. The novel sulphonylurea, glimepiride, gives rise to a longer lasting reduction in the
Altan +75 more
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Boscisucrophage: A Natural SGLT1/2 Inhibitor From Boscia senegalensis for Managing Type 2 Diabetes
Food Science &Nutrition, Volume 14, Issue 3, March 2026.Boscisucrophage (BSP) significantly reduced blood glucose and HbA1c, increased urine glucose excretion, and improved functional symptoms in T2DM patients resistant to oral antihyperglycemic drugs. BSP showed no adverse effects on liver or kidney function.
Bruno Eto +11 more
wiley +1 more source