Results 71 to 80 of about 382,034 (365)

Modulação do sistema glutamatérgico por cisplatina em células de glioma humano e astrócitos corticais de ratos [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-graduação em Neurociências, Florianópolis, 2013.Gliomas malignos constituem um grupo heterogêneo de tumores, com origem em precursores ...
Oliveira, Karen Andrinéia de
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Genetic and molecular epidemiology of adult diffuse glioma

Nature Reviews Neurology, 2019
The WHO 2007 glioma classification system (based primarily on tumour histology) resulted in considerable interobserver variability and substantial variation in patient survival within grades.
A. Molinaro, Jennie W. Taylor, J. Wiencke, M. Wrensch   +3 more
semanticscholar   +1 more source

Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4

Autophagy, 2021
Glioma is the most common primary malignant brain tumor with poor survival and limited therapeutic options. The non-psychoactive phytocannabinoid cannabidiol (CBD) has been shown to be effective against glioma; however, the molecular target and mechanism
Tengfei Huang, Tianqi Xu, Yangfan Wang, Yan Zhou, Dandan Yu, Zhiyuan Wang, Linfang He, Zhangpeng Chen, Yaliang Zhang, D. Davidson, Yuyuan Dai, C. Hang, Xiangyu Liu, C.-Q. Yan   +13 more
semanticscholar   +1 more source

Tracking Tumor Evolution in Glioma through Liquid Biopsies of Cerebrospinal Fluid

Nature, 2019
Diffuse gliomas are the most common malignant brain tumours in adults and include glioblastomas and World Health Organization (WHO) grade II and grade III tumours (sometimes referred to as lower-grade gliomas).
Alexandra M Miller, Ronak H. Shah, E. Pentsova, Maryam Pourmaleki, S. Briggs, Natalie Distefano, Youyun Zheng, Anna Skakodub, S. Mehta, Carl Campos, Wan-Ying Hsieh, S. D. Selcuklu, Lilan Ling, Fanli Meng, Xiaohong Jing, A. Samoila, T. Bale, D. Tsui, C. Grommes, A. Viale, M. Souweidane, V. Tabar, C. Brennan, A. Reiner, M. Rosenblum, K. Panageas, L. Deangelis, R. Young, M. Berger, I. Mellinghoff   +29 more
semanticscholar   +1 more source

Electrophysiological characterization of cerebral glioma pre and post surgery

, 2023
reservedCaratterizzazione elettrofisiologica del glioma cerebrale pre e post ...
MANTOVANI, CARLO
core  

Glioma of the Retina [PDF]

The American Journal of the Medical Sciences, 1906
n ...
openaire   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Temozolomide promotes glioblastoma stemness expression through senescence-associated reprogramming via HIF1α/HIF2α regulation

Cell Death and Disease
A critical challenge in glioblastoma multiforme (GBM) treatment is that tumors recurring after temozolomide (TMZ) therapy become more malignant, exhibiting increased invasiveness and stemness compared to the primary tumor.
Pan Wang, Bin Liao, Sheng Gong, HaiYan Guo, Lu Zhao, Jie Liu, Nan Wu   +6 more
doaj   +1 more source

LONGITUDINAL MOLECULAR TRAJECTORIES OF DIFFUSE GLIOMA IN ADULTS

Nature, 2019
The evolutionary processes that drive universal therapeutic resistance in adult patients with diffuse glioma remain unclear1,2. Here we analysed temporally separated DNA-sequencing data and matched clinical annotation from 222 adult patients with glioma.
F. Barthel, K. Johnson, F. Varn, A. Moskalik, Georgette Tanner, E. Kocakavuk, K. Anderson, O. Abiola, K. Aldape, K. Alfaro, D. Alpár, S. Amin, D. Ashley, P. Bandopadhayay, J. Barnholtz-Sloan, R. Beroukhim, C. Bock, P. Brastianos, D. Brat, A. Brodbelt, Alexander F. Bruns, K. Bulsara, A. Chakrabarty, A. Chakravarti, Jeffrey H. Chuang, E. Claus, E. Cochran, J. Connelly, J. Costello, G. Finocchiaro, M. Fletcher, P. French, H. Gan, M. Gilbert, P. Gould, M. Grimmer, A. Iavarone, Azzam Ismail, M. Jenkinson, M. Khasraw, Hoon Kim, M. Kouwenhoven, P. LaViolette, Meihong Li, P. Lichter, K. Ligon, A. Lowman, T. Malta, T. Mazor, K. McDonald, A. Molinaro, D. Nam, Naema Nayyar, H. Ng, C. Ngan, S. Niclou, J. Niers, H. Noushmehr, J. Noorbakhsh, D. Ormond, Chul-Kee Park, L. Poisson, R. Rabadán, B. Radlwimmer, G. Rao, G. Reifenberger, J. Sa, M. Schuster, Brian Shaw, S. Short, P. Smitt, A. Sloan, M. Smits, Hiromichi Suzuki, G. Tabatabai, Erwin G. Van Meir, C. Watts, M. Weller, P. Wesseling, B. Westerman, G. Widhalm, A. Woehrer, W. Yung, G. Zadeh, J. Huse, J. Groot, Lucy F. Stead, R. Verhaak   +87 more
semanticscholar   +1 more source