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Effects of Glioma Cells on Maturation of Dendritic Cells

Journal of Neuro-Oncology, 2002
We investigated whether glioma cells affected the maturation of dendritic cells (DCs). First, DCs phenotypes were analyzed using FACScan. Incubation of both human and mouse immature DCs with glioma cells altered their expression of cell surface molecules, whereas expression of cell surface molecules by mature mouse and human DCs was not affected by ...
Tetsuro, Kikuchi   +2 more
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Cell-Based Immunotherapy of Gliomas

2018
Current cell-based immunotherapeutic strategies attempt to produce and maintain an immune response against glioma cells by artificially stimulating the immune system using passive and/or active approaches. Cellular immunotherapy is taken to mean the administration of live immune cells that either have immune effector capabilities themselves (passive ...
Richard G, Everson   +2 more
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Progenitor cells and glioma formation

Current Opinion in Neurology, 2001
The gliomas are a collection of tumors that arise within the central nervous system and have characteristics similar to astrocytes, oligodendrocytes, or their precursors. Whether or not the glial characteristics of these tumors mean that they arise from the differentiated glia that they resemble or their precursors has been debated.
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The tropism of embryoid body cells for glioma cells

NeuroReport, 2007
It has been demonstrated that several types of adult stem cells have a common attribute of tropism for gliomas. In our study, we provided evidence that embryonic stem cell-derived embryoid body (EB) cells also exhibited a tropism for gliomas. Chemotaxis assays and organotypic hippocampal slice culture experiments showed that EB cells were attracted by ...
Xiao-Bo, Li   +7 more
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Bradykinin induces hyperpolarizations in rat glioma cells and in neuroblastoma × glioma hybrid cells

Brain Research, 1982
The effect of the nonapeptide bradykinin on the membrane potential of permanent cell lines from neural origin was studied. A hyperpolarizing response of 10-30 s duration was produced when bradykinin was iontophoretically applied onto polyploid rat glioma cells (clone C6-4-2).
G, Reiser, B, Hamprecht
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Signaling Determinants of Glioma Cell Invasion

2012
Tumor cell invasiveness is a critical challenge in the clinical management of glioma patients. In addition, there is accumulating evidence that current therapeutic modalities, including anti-angiogenic therapy and radiotherapy, can enhance glioma invasiveness.
Aneta, Kwiatkowska, Marc, Symons
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Mesenchymal Properties of Glioma Cell Lines

Bulletin of Experimental Biology and Medicine
Screening of cell surface markers of three glioma cell lines (astrocytoma 1321N1, glioblastoma T98g, and glioblastoma astrocytoma U373 MG) was performed. Glioma cells expressed common mesenchymal cell markers, although the expression levels varied between the cell lines.
I V, Kholodenko   +5 more
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Autophagy in Glioma Cells

2014
Autophagy is an intracellular lysosomal degradation process controlled by a number of highly conserved autophagy-related genes (ATG) and tightly regulated by multiple mechanisms. This process could be induced by various cellular stress-mediated signaling pathways involved in nutrient signaling, growth factor status, energy sensing, hypoxia, oxidative ...
Iwona Anna Ciechomska   +2 more
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[Glioma Cell Biology].

No shinkei geka. Neurological surgery, 2021
In this review, I summarized the biology of gliomas. Through past clinical and basic studies, I reviewed the evidence of the cell of origin of gliomas and the presence of brain tumor-initiating cells in gliomas, which are driven by multiple genomic alterations.
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Glioma Cell Biology

2014
The inner space: Molecular mechanisms driving the malignant phenotype of glioma cells: Cancer stem cells and glioblastoma.- Epigenetic changes in gliomas.- Signaling cascades and transcription factors driving the malignant phenotype of glioma cells.- MicroRNAs in molecular pathology of gliomas.- Autophagy in glioma cells.- Partnership: Glioma cell ...
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