Quantification of neurodegeneration by measurement of brain-specific proteins [PDF]
, 2003 Quantification of neurodegeneration in animal models is typically assessed by time-consuming and observer-dependent immunocytochemistry. This study aimed to investigate if newly developed ELISA techniques could provide an observer-independent, cost ...
Baker, D. +5 more
core +1 more source
Molecular assessment of intermediate filamented protein as a detective marker of quails' histopathological brain lesions [PDF]
Iraqi Journal of Veterinary SciencesThe nervous system plays a crucial role in regulating most of the body's vital functions. Stress factor or infection may affect the Nervous System, which includes both the central and peripheral systems.
Hadeel Al-Sabaawy +2 more
doaj +1 more source
Structural imaging biomarkers of sudden unexpected death in epilepsy. [PDF]
, 2015 Sudden unexpected death in epilepsy is a major cause of premature death in people with epilepsy. We aimed to assess whether structural changes potentially attributable to sudden death pathogenesis were present on magnetic resonance imaging in people who ...
Balestrini, Simona +12 more
core +3 more sources
The various routes to functional regeneration in the central nervous system [PDF]
, 2020 © The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Echeverri, K.
Echeverri, Karen
core +1 more source
Alzheimer and vascular brain diseases: Focal and diffuse subforms. [PDF]
, 2015 Alois Alzheimer is best known for his description of the pre-senile neurodegenerative disease named after him. However, his previous interest in vascular brain diseases, underlying cognitive and behavioral changes, was very strong. Besides describing the
Engelhardt, Eliasz, Grinberg, Lea T
core +2 more sources
A Synthesized Glucocorticoid- Induced Leucine Zipper Peptide Inhibits Retinal Müller Cell Gliosis
Frontiers in Pharmacology, 2018 Purpose: The anti-inflammatory activities of protein glucocorticoid-induced leucine zipper (GILZ) have been demonstrated in vivo and in vitro. Here, we examined the potential effect of a synthetic peptide derived from the leucine zipper motif and proline-
Ruiping Gu +7 more
doaj +1 more source
Gliosis and Neurodegenerative Diseases: The Role of PET and MR Imaging
Frontiers in Cellular Neuroscience, 2020 Glial activation characterizes most neurodegenerative and psychiatric diseases, often anticipating clinical manifestations and macroscopical brain alterations. Although imaging techniques have improved diagnostic accuracy in many neurological conditions,
Carlo Cavaliere +5 more
doaj +1 more source
Annexin A1 Regulates Retinal Gliosis in Diabetic Retinopathy
Biology and Life Sciences Forum, 2023 In diabetic retinopathy (DR), Müller cell gliosis contributes to retinal degeneration and inflammation. In this context, we highlight annexin A1 (AnxA1), an anti-inflammatory protein able to regulate neurodegeneration and angiogenesis; however, its ...
Rafael André da Silva +4 more
doaj +1 more source
The novel MAPT mutation K298E:mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons [PDF]
, 2013 Frontotemporal lobar degeneration (FTLD) consists of a group of neurodegenerative diseases characterized by behavioural and executive impairment, language disorders and motor dysfunction.
Calo, Laura +14 more
core +4 more sources
Frontiers in Pharmacology, 2022 Age-related macular degeneration (AMD) is nowadays considered among the retinal diseases whose clinical management lacks established treatment approaches, mainly for its atrophic (dry) form.
Alberto Melecchi +8 more
doaj +1 more source