Results 101 to 110 of about 17,498 (250)

Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling

Brain and Behavior, Volume 16, Issue 2, February 2026.
Histone methylation and acetylation modulate gene expression by inducing chromatin condensation or relaxation, which in turn regulates transcriptional activity and impacts neurogenesis. ABSTRACT Aims The purpose of this review is to examine how epigenetic regulation particularly chromatin modification and histone methylation controls gene expression ...
Degisew Yinur Mengistu, Biniam Moges Eskeziyaw   +1 more
wiley   +1 more source

An intron nucleotide sequence variant in a cloned β⁺-thalassaemia globin gene [PDF]

, 1981
David Westaway, Robert Williamson
openalex   +1 more source

Creating New β-Globin-Expressing Lentiviral Vectors by High-Resolution Mapping of Locus Control Region Enhancer Sequences [PDF]

, 2020
Richard A. Morgan, Feiyang Ma, Mildred J. Unti, Devin Brown, Paul G. Ayoub, Curtis Tam, Lindsay Lathrop, Bamidele Aleshe, Ryo Kurita, Yukio Nakamura, Shantha Senadheera, Ryan L. Wong, Roger P. Hollis, Matteo Pellegrini, Donald B. Kohn   +14 more
openalex   +1 more source

Archipelago Method for Variant Set Association Test Statistics

Genetic Epidemiology, Volume 50, Issue 1, February 2026.
ABSTRACT Variant set association tests (VSAT), especially those incorporating rare variants via variant collapse, are invaluable in genetic studies. However, unlike Manhattan plots for single‐variant tests, VSAT statistics lack intrinsic genomic coordinates, hindering visual interpretation.
Dylan Lawless, Ali Saadat, Mariam Ait Oumelloul, Luregn J. Schlapbach, Jacques Fellay   +4 more
wiley   +1 more source

Predictive biomarkers for regression in women undergoing active surveillance for cervical intraepithelial neoplasia grade 2: A prospective multicenter study in Italy

International Journal of Cancer, Volume 158, Issue 3, Page 587-596, 1 February 2026.
What's new? Cervical intraepithelial neoplasia grade 2 (CIN2) lesions can spontaneously regress, especially in women aged under 30. Better predictive biomarkers are needed to improve risk stratification for active surveillance. This prospective multicenter cohort study evaluated HPV genotyping, p16/ki67 expression, and FAM19A4/miR124‐2 methylation ...
Helena Frayle, Silvia Gori, Alessio Pagan, Marika Soldà, Cesare Romagnolo, Egle Insacco, Licia Laurino, Mario Matteucci, Giuseppe Sordi, Enrico Busato, Manuel Zorzi, Tiziano Maggino, Annarosa Del Mistro, CIN2 Study Working Group, Annarosa Del Mistro, Helena Frayle, Silvia Gori, Rossana Trevisan, Alessio Pagan, Justyna Wojciechowska, Enrico Busato, Tiziano Maggino, Marika Soldà, Cesare Romagnolo, Licia Laurino, Pamela Zambenedetti, Egle Insacco, Mario Matteucci, Maria Teresa Gervasi, Giuseppe Sordi, Marco Torrazzina, Manuel Zorzi, Daria Minucci   +32 more
wiley   +1 more source

Characterization of the DNase I hypersensitive site 3' of the human beta globin gene domain [PDF]

, 1993
DE Fleenor, Russel E. Kaufman
openalex   +1 more source

Prevalence of Severe Thalassemia and Performance of Prenatal Screening Tests Among Pregnant Women at Siriraj Thalassemia Center in Thailand

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Severe thalassemia remains a significant public health concern in Southeast Asia. Prenatal screening is an effective strategy for early detection and prevention. This study aimed to determine the prevalence of severe thalassemia and assess the performance of prenatal screening at the Siriraj Thalassemia Center, Siriraj Hospital, Thailand.
Kwandao Malasai, Usa Chaikledkaew, Pattarawalai Talungchit, Sitaporn Youngkong, Wanvisa Udomsinprasert, Chanin Limwongse, Jiraphun Jittikoon   +6 more
wiley   +1 more source

A beta-thalassemia carrier with normal sequence within the beta-globin gene [letter] [PDF]

, 1990
S Murru, Georgios Loudianos, Aili Cao, Simona Vaccargiu, Mario Pirastu, GV Sciarratta, Steven J. Agosti, MI Parodi   +7 more
openalex   +1 more source

Functional characterization of NRT1/PTR FAMILY transporters: looking for a needle in a haystack

New Phytologist, Volume 249, Issue 3, Page 1124-1144, February 2026.
Summary NRT1/PTR FAMILY (NPF) transporters play crucial roles in plant physiology and development due to their involvement in nitrogen nutrition and their ability to transport multiple signaling molecules and metabolites. Whereas most eukaryotic and prokaryotic NPF orthologs are peptide transporters, most flowering plant NPF transport other substrates ...
Laura Morales de Los Ríos, The Dan Pham, Thibaut Perez, Myriam Ben Amar, Claire Corratgé‐Faillie, François Barbier, Benoit Lacombe   +6 more
wiley   +1 more source

A Patient With Coinheritance of Alpha-Globin Gene Triplication and IVSI-5 Mutation of Beta-Globin Gene [PDF]

, 2015
Majid Naderi, Ibrahim Miri-Moghaddam, Akbar Dorgalaleh, Shaban Alizadeh, Shadi Tabibian, Pishjoo Masoud   +5 more
openalex   +1 more source