Results 111 to 120 of about 7,527 (191)

The Use of First‐Void Urine to Screen Women Aged 60–79 for HPV in the UK: The Catch‐Up Screen Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 4, Page 814-822, March 2026.
ABSTRACT Objective Almost half the deaths from cervical cancer in the UK are among women aged over 65 who were already above the upper age of screening when primary HPV screening was introduced in the UK in 2019. Our aim is to test the feasibility of a national catch‐up HPV testing programme.
Christine Rake   +12 more
wiley   +1 more source

Stroke burden and functional impacts in adults with sickle cell disease

open access: yesBritish Journal of Haematology, Volume 208, Issue 3, Page 1063-1073, March 2026.
Stroke was identified in 4.6% of 454 adults with sickle cell disease. Stroke occurred not only across HbSS/Sβ0 phenotypes but also HbSC/Sβ+ as well, challenging traditional assumptions. Stroke was associated with long‐term functional impairment, including cognitive deficits and higher disability scores.
Jonathan St‐Onge   +12 more
wiley   +1 more source

Neurotrophic Modulation Restores Motor and Developmental Defects in Zebrafish Models of ints11 Deficiency

open access: yesJournal of Neurochemistry, Volume 170, Issue 3, March 2026.
The study investigates the functional consequences of INTS11 loss‐of‐function (LoF), a genetic alteration linked to neurodevelopmental disorder (NDD), using zebrafish as an in vivo model. To model ints11 deficiency, two complementary approaches are applied: morpholino‐mediated knock‐down and CRISPR–Cas9 transient knock‐out, establishing ints11‐LoF ...
Anna Pistocchi   +9 more
wiley   +1 more source

Placental iron utilisation in fetal growth restriction: alterations in mitochondrial haem synthesis and iron–sulphur cluster assembly pathways

open access: yesThe Journal of Physiology, Volume 604, Issue 5, Page 2229-2249, 1 March 2026.
Abstract figure legend Altered iron handling and mitochondrial pathways in FGR placentas. Placental tissue from FGR pregnancies showed increased expression of iron importers, transferrin and divalent metal transporter 1, and decreased expression of the iron exporter ferroportin, suggesting that the FGR placenta is retaining iron to meet its own ...
Veronica B. Botha   +5 more
wiley   +1 more source

Cooperative ligand binding in a bacterial heme-based oxygen sensor. [PDF]

open access: yesJ Biol Chem
Hoque NJ   +9 more
europepmc   +1 more source

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