Results 71 to 80 of about 7,527 (191)

Comparison of MLPA Method for Detection of Known and Unknown Deletions in Beta Globin Gene Cluster with Old Methods (REAL-TIME, RFLP, Gap-PCR)

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2008
Background and Objectives Thalassaemia is one of the most common single gene disorders, which is most prevalent in the Mediterranean, the Middle East, Indian subcontinent (malaria belt). One of the mutations that result in Thalassaemia is the deletion in
R R Alimohammadi, M Raiesi, A Ebrahimi, S Fallah, S Kianfar, M Masoudifar, S Jamali, S Babashah, M Karimipour, R Mahdian, S Zeinali   +10 more
doaj  

PROBING REDUCING POWER FOR FERRYL PHYTOGLOBINS OF SEVERAL PHENOLIC COMPOUNDS USING THEIR KINETIC PROFILES ASSISTED BY CHEMOMETRIC METHODS

Studia Universitatis Babes-Bolyai Chemia, 2017
Several phenolic compounds belonging to different classes were comparatively analyzed for their ability to reduce ferryl forms of three non-symbiotic phytoglobins which were generated in situ by hydrogen peroxide and thus acting as enzymes.
Galaba NAUMOVA-LEȚIA, Augustin C. MOȚ   +1 more
doaj   +1 more source

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

Prenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij, Frans J. W. Smiers, Tamara T. Koopmann, Ingrid Krapels, Kaatje LePoole, Enrico Lopriore, Johanna M. Middeldorp, Claudia S. Ootjers, Volkher Scharnhorst, Hubertina C. J. Scheepers, Cornelis L. Harteveld, E. J. T. (Joanne) Verweij   +11 more
wiley   +1 more source

Prenatal Exome Sequencing Identifies Dual Maternal‐Fetal Diagnosis of HbF Mission Bay, a Novel HBG2 Variant Associated With Methemoglobinemia, Hypoxia and Hemolytic Anemia

Prenatal Diagnosis, EarlyView.
ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear, Billie Lianoglou, Ugur Hodoglugil, W. Patrick Devine, Ashutosh Lal, Juan Gonzalez, Teresa N. Sparks   +6 more
wiley   +1 more source

Human erythroid progenitors from adult bone marrow and cord blood in optimized liquid culture systems respectively maintained adult and neonatal characteristics of globin gene expression

Biological Research, 2007
In vitro suspension culture procedures for erythroid progenitor cells make it possible for us to obtain large cultures of erythrocyte populations for the investigation of globin gene switching.
XIN ZHANG, YAN-NI MA, JUN-WU ZHANG
doaj  

Deep Proteomic Profiles of the Antarctic Diatom Fragilariopsis Cylindrus Under Varying Iron and Manganese Conditions

PROTEOMICS, EarlyView.
ABSTRACT Fragilariopsis cylindrus is a key diatom in the Southern Ocean, where low iron and manganese availability constrain primary production and biogeochemical activity. The molecular mechanisms used by polar diatoms, including F. cylindrus, to cope with trace metal limitations remain largely unexplored.
Loay J. Jabre, Elden Rowland, J. Scott P. McCain, Erin M. Bertrand   +3 more
wiley   +1 more source

Chicken globin gene number

Nucleic Acids Research, 1976
Using complementary DNA prepared from adult chicken globin messenger RNA, we show the existence of 2-3 non-cross-hybridising globin sequences in the chicken genome, each of which is present in only one copy per haploid genome. This was done by solution hybridization to total DNA under conditions of cDNA excess.
J F, Jackson, P, Tolstoshev, R, Williamson, D, Hendrick   +3 more
openaire   +3 more sources

Evaluation of the Quality and Suitability of Self‐Collected Vaginal and Urine Samples for Human Papillomavirus Testing: A Prospective Matched Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the analytical suitability of different storage and laboratory processes of self‐samples for an HPV assay. Design Prospective matched study. Setting Royal London Hospital Colposcopy Clinic. Population One hundred seventy seven patients aged 25–65 years referred to colposcopy due to their screening results (abnormal ...
Kim Chu, Sofia Vidali, Anna Parberry, Michelle Saull, Krishna Patel, Hannah Mohy‐Eldin, Laura White, Adam Brentnall, Peter Sasieni, Rhian Gabe, Ranjit Manchanda, Jack Cuzick, Belinda Nedjai   +12 more
wiley   +1 more source

Cardiovascular Plasticity and Adaptation of High‐Altitude Birds and Mammals

Integrative Zoology, EarlyView.
This schematic depicts the cardiovascular adaptations of mammals and birds to high‐altitude hypoxia. It highlights key phenotypic changes in oxygen transport and cardiac responses, driven by molecular mechanisms including transcriptional regulation and genetic modifications.
Huishang She, Yanhua Qu
wiley   +1 more source

Insights into Hemoglobin Polymorphism and Related Functional Effects on Hematological Pattern in Mediterranean Cattle, Goat and Sheep

Diversity, 2010
This report is a review of some of the results obtained over the course of 20 years spent investigating hemoglobin phenotypes and the related functional effects on hematological patterns in ruminant breeds.
Elisa Pieragostini, Ingrid Alloggio, Ferruccio Petazzi   +2 more
doaj   +1 more source