Results 151 to 160 of about 2,192 (198)

Removal of subretinal strands without creating an intentional retinal hole: A case report. [PDF]

Am J Ophthalmol Case Rep
Sakata S, Sakanishi Y, Inoue K, Ebihara N.   +3 more
europepmc   +1 more source

Human globozoospermia-related genes and their role in acrosome biogenesis.

WIREs Mechanisms of Disease, 2022
The mammalian acrosome is a secretory vesicle attached to the sperm nucleus whose fusion with the overlying plasma membrane is required to achieve fertilization.
R. Moreno
semanticscholar   +5 more sources

Intracytoplasmic sperm injection in partial globozoospermia

Fertility and Sterility, 2012
To compare the outcome of intracytoplasmic sperm injection (ICSI) in patient couples where the male partner has partial globozoospermia with the outcome in a general ICSI population.Case-control study.Center for Reproductive Medicine, Radboud University Nijmegen Medical Center, the Netherlands, a tertiary referral center.Between 1997 and 2005, 42 ...
Jan C M Hendriks, Liliana Ramos, Jan A M Kremer   +2 more
exaly   +5 more sources

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Loss of SPACA1 function causes autosomal recessive globozoospermia by damaging the acrosome–acroplaxome complex

Human Reproduction, 2021
STUDY QUESTION Is the sperm acrosome membrane-associated protein 1 (SPACA1) gene critical to human globozoospermia? SUMMARY ANSWER The biallelic loss-of-function (variant of SPACA1) causes globozoospermia as a result of acrosome-acroplaxome complex ...
Pingping Chen, Hexige Saiyin, Ruona Shi   +2 more
exaly   +2 more sources

Evaluation and treatment of familial globozoospermia in five brothers

Fertility and Sterility, 2004
To document the pathology of five siblings with complete globozoospermia and to report the effectiveness of repeated intracytoplasmic sperm injection (ICSI) treatment as therapy.Case report.A tertiary center for assisted reproduction.Five siblings with globozoospermia.Twenty cycles of repeated ICSI treatment.
Christopher L R Barratt
exaly   +5 more sources

Search for mutations involved in human globozoospermia* [PDF]

Human Reproduction, 2005
Globozoospermia is a severe form of teratozoospermia characterized by round-headed sperm with an absence of acrosomes. Family cases of globozoopermia suggest that this pathology has genetic origins, but the mode of inheritance remains unknown. So far, no responsible genes have been identified.
Yves Ménézo, Stéphane Viville, Ménézo Yves   +2 more
exaly   +3 more sources

Assessment of Atg7 and LC3II/LC3, as The Markers of Autophagy, in Sperm of Infertile Men with Globozoospermia: A Case-Control Study

Cell journal, 2021
Objective Assessment of relationship between LC3II/LC3 and Autophagy-related 7 (Atg7) proteins, as markers of autophagy, as well as evaluating the sperm parameters and DNA fragmentation in spermatozoa of infertile men with globozoospermia.
Shaghayegh Foroozan-Boroojeni, M. Tavalaee, Z. Zakeri, R. Lockshin, M. Nasr-Esfahani   +4 more
semanticscholar   +1 more source

Awareness and reporting of globozoospermia among in vitro fertilization and andrology laboratories: A national survey

Andrologia, 2021
Globozoospermia (GZ) is a rare disorder found in less than 0.1% of infertile men in which spermatozoa lack acrosomes necessary for penetration of an oocyte.
John Ernandez, C. Gu, M. Kathrins
semanticscholar   +1 more source

Expression of sperm PLCζ and clinical outcomes of ICSI-AOA in men affected by globozoospermia due to DPY19L2 deletion.

Reproductive Biomedicine Online, 2017
Globozoospermia is characterized by the presence of 100% acrosomeless round-headed spermatozoa in an ejaculate. Failed fertilization after intracytoplasmic sperm injection (ICSI) is commonly reported for globozoospermic couples and can be overcome by ...
M. Tavalaee, M. Nomikos, F. A. Lai, M. Nasr-Esfahani   +3 more
semanticscholar   +2 more sources