Results 161 to 170 of about 2,192 (198)

Globozoospermia Syndrome : Two Case Reports

Lebanese Medical Journal, 2014
Globozoospermia is a rare but severe cause of male infertility. The presence of 100% round-headed spermatozoa and lack of acrosome are the diagnostic criteria of total globozoospermia. The pathogenesis of globozoospermia most probably originates in spermiogenesis, specifically in acrosome formation and sperm head elongation.
Sanam, Moradan, Behpour, Yousefi
openaire   +2 more sources

Chromatin Structure in Globozoospermia: A Case Report

Journal of Andrology, 2001
ABSTRACT: Sperm nuclear abnormalities in patients with globozoospermia have not been well characterized and may lead to the high rates of fertilization failure and embryo loss reported in patients with this form of teratozoospermia. This study used transmission electron microscopy (TEM), the sperm chromatin structure assay (SCSA), and single cell gel ...
K L, Larson, J D, Brannian, N P, Singh, J A, Burbach, L K, Jost, K P, Hansen, D O, Kreger, D P, Evenson   +7 more
openaire   +2 more sources

Globozoospermia is associated with chromatin structure abnormalities: Case report [PDF]

Human Reproduction, 2002
A recent study has shown normal sperm chromatin structure in a patient with globozoospermia. However, the poor success rate following intracytoplasmic sperm injection (ICSI) with the use of this sperm suggests that sperm nuclear abnormalities may be present.
Enzo Vicari, Adele De Palma, N Burrello   +2 more
exaly   +4 more sources

Deletion of dpy-19 like 2 (DPY19L2) gene is associated with total but not partial globozoospermia.

Reproduction, Fertility and Development, 2020
The dpy-19 like 2 (DPY19L2) gene is the most common genetic cause of globozoospermia characterised by the production of round-headed spermatozoa without an acrosome.
F. Alimohammadi, Mahya Ebrahimi Nasab, Alemeh Rafaee, M. Hashemi, M. Totonchi, A. Mohseni Meybodi, M. S. Sadighi Gilani, M. Sabbaghian   +7 more
semanticscholar   +1 more source

Proteomic Analysis of Dpy19l2‐Deficient Human Globozoospermia Reveals Multiple Molecular Defects

PROTEOMICS - Clinical Applications, 2019
To investigate the differences in protein expression between Dpy19l2‐deficient human globozoospermia and normozoospermia.
Yueshuai Guo, Jiayin Jiang, Haotian Zhang, Yang Wen, Hao Zhang, Yiqiang Cui, Jianyu Tian, Min Jiang, Xiaofei Liu, Gaigai Wang, Yan Li, Zhibin Hu, Zuo-min Zhou, J. Sha, Daozhen Chen, Xiaoyu Yang, Xuejiang Guo   +16 more
semanticscholar   +1 more source

Sperm chromosome aneuploidy analysis in a man with globozoospermia

Fertility and Sterility, 2003
To determine the frequencies of chromosome aneuploidy and diploidy in sperm from a male with globozoospermia.Assessment of sperm chromosome aneuploidy and diploidy frequencies by multicolor fluorescence in situ hybridization (FISH) analysis.University research laboratory.An infertile patient with round-headed sperm (globozoospermia).Sperm samples were ...
Renée H, Martin, Calvin, Greene, Alfred W, Rademaker   +2 more
openaire   +2 more sources

Corrigendum to: Deletion of dpy-19 like 2 (DPY19L2) gene is associated with total but not partial globozoospermia.

Reproduction, Fertility and Development, 2020
The dpy-19 like 2 (DPY19L2) gene is the most common genetic cause of globozoospermia characterised by the production of round-headed spermatozoa without an acrosome.
F. Alimohammadi, Mahya Ebrahimi Nasab, Alemeh Rafaee, M. Hashemi, M. Totonchi, A. Mohseni Meybodi, M. S. Sadighi Gilani, M. Sabbaghian   +7 more
semanticscholar   +1 more source

Molecular cytogenetic and genetic aspects of globozoospermia: a review

Andrologia, 2012
Infertility is estimated to affect up to 15% of couples of reproductive age. Among the male factors, globozoospermia (also called round-headed sperm syndrome) is a rare type of teratozoospermia accounting for
A, Perrin, C, Coat, M H, Nguyen, M, Talagas, F, Morel, J, Amice, M, De Braekeleer   +6 more
openaire   +2 more sources

[Globozoospermia syndrome: an update].

Zhonghua nan ke xue = National journal of andrology, 2011
Globozoospermia syndrome is a rare teratozoospermia, with an incidence of less than 0.1%. It is characterized by round sperm head, absence of acrosome, and messy sperm body and tail, but without other special clinical features. The absence of acrosome could reduce the activation ability of oocytes, and consequently decrease their fertilization ability.
Yan-wei, Sha, Yue-qiang, Song, Bin, Han
openaire   +1 more source

[Molecular genetics of globozoospermia: an update].

Zhonghua nan ke xue = National journal of andrology, 2012
Globozoospermia, as a severe teratozoospermia caused by gene mutations, is a rare congenital disease with main clinical manifestations of the round head of sperm and abnormality or absence of acrosome, and its precise mechanism is not yet clear. Studies show that the pathogenic genes associated with globozoospermia include SPATA16, PICK1, GOPC, Hrb ...
Lei, Wan, Li-mei, An, Xin-yi, Xia
openaire   +1 more source