Results 121 to 130 of about 7,660 (199)
The Post-Ischemic Increase in GluA2 Ser880 Phosphorylation Involves NADPH Oxidase
Journal of Pharmaceutics and Therapeutics, 2018 Most 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl) propanoic acid receptors (AMPARs) expressed on adult hippocampal pyramidal neurons contain the edited form of GluA2 (Q607R) and are thus impermeable to Ca2+/Zn2+ entry. Following ischemic injury, these receptors undergo a subunit composition change, switching from a GluA2-containing Ca2+/Zn2 ...
Darrell A. Jackson +3 more
openaire +2 more sources
The Journal of Clinical InvestigationEarly-life seizures (ELSs) can cause permanent cognitive deficits and network hyperexcitability, but it is unclear whether ELSs induce persistent changes in specific neuronal populations and whether these changes can be targeted to mitigate network ...
Bo Xing +8 more
doaj +1 more source
Examples of the evolution of radial signal profiles of GluA2 ATD.
, 2013 Circles are experimental data, for clarity showing only every 2nd data point of every 2nd scan, and solid lines are the best-fit c(s) models, with increasing color temperature indicating later times.
Carla Glasser (498485) +4 more
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, 2017 Hyperammonemia contributes to altered neurotransmission and cognition in patients with hepatic encephalopathy. Hyperammonemia in rats affects differently high- and low-affinity AMPA receptors (AMPARs) in cerebellum.
Vicente Felipo +11 more
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Adult and juvenile rats differentially express mPFC GluA2 following traumatic memory retrieval [PDF]
, 2019 To advance our understanding of how traumatic memories are modulated between adults and juveniles, we characterize the AMPAr subunits, GluA1, GluA2, GluA3 in the mPFC of rodents following traumatic memory retrieval.
Rodriguez, Edgar
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LY37 increased GluA1 or GluA2 colocalization with PSD95 but not synapsin I.
, 2013 (A) Immunofluorescent images show colocalization of surface GluA1 or GluA2 receptor (red: Dylight-594) with PSD95 (green: Alexa-594) in DIV15–17 primary PFC neurons. Scale bar = 10 µm for most of the images in A and B and scale bar = 5 µm in the enlarged
Huaixing Wang (402224) +5 more
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Tyro3 promotes the maturation of glutamatergic synapses
Frontiers in NeuroscienceThe receptor tyrosine kinase Tyro3 is abundantly expressed in neurons of the neocortex, hippocampus, and striatum, but its role in these cells is unknown. We found that neuronal expression of this receptor was markedly up-regulated in the postnatal mouse
Sheng Miao +9 more
doaj +1 more source
Effect of GluA2 RNAi on the dendritic morphology of E6 chicken lumbar motoneurons.
, 2013 A–D) Infection of chicken embryos with the RCASBP(B)-RFP-GluA2 RNAi construct has no effect on the dendritic complexity of E6 motoneurons including dendritic arbor/cell (A), number of primary dendrites (B), number of branches (C), and number of ends (D).
Sheryl L. White (296193) +4 more
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, 2018 The ionotropic glutamate receptor GluA2 is considered to be an attractive target for positive allosteric modulation for the development of pharmacological tools or cognitive enhancers.
Kathrine Voigt Hansen +23 more
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Diffusion characteristics of the GluA2 subunit of the AMPAR in inhibitory and excitatory synapses.
, 2012 (A) Trajectories of GluA2-coupled QDs in excitatory (red), inhibitory (green) synapses or in extrasynaptic compartment (black). Scale, 0.4 µm. (B) Cumulative probabilities of diffusion coefficients of GluA2 in inhibitory (green) and excitatory synapses ...
Antoine Triller (142658) +4 more
core +1 more source