Results 21 to 30 of about 42,521 (302)

Glucagon-like peptide-1, glucagon-like peptide-2, and lipid metabolism [PDF]

Current Opinion in Lipidology, 2016
Glucagon-like peptide-1 (GLP-1) is the best known incretin hormone able to potentiate glucose-induced insulin secretion. Moreover, GLP-1 is currently under intensive investigation as a potential crucial mediator of beneficial metabolic effects after bariatric surgery, because of its eating inhibitory, antiobesity, and antidiabetes effects.
Thomas A. Lutz, Elena Osto
openaire   +2 more sources

Gastrointestinal peptides in children before and after hematopoietic stem cell transplantation

BMC Cancer, 2020
Background Gastrointestinal tract function and it’s integrity are controlled by a number of peptides whose secretion is influenced by severe inflammation. In stomach the main regulatory peptide is ghrelin.
Szymon Skoczeń, Magdalena Rej, Kinga Kwiecińska, Danuta Pietrys, Przemysław J. Tomasik, Małgorzata Wójcik, Wojciech Strojny, Agnieszka Dłużniewska, Katarzyna Klimasz, Kamil Fijorek, Michał Korostyński, Marcin Piechota, Walentyna Balwierz   +12 more
doaj   +1 more source

Glucagon‐like peptides activate hepatic gluconeogenesis [PDF]

FEBS Letters, 1987
Piscine (anglerfish, catfish, coho salmon) glucagon‐like peptides (GLPs), applied at 3.5 nM, stimulate (1.1–1.9‐fold) flux through gluconeogenesis above control levels in isolated trout and salmon hepatocytes. Human GLP‐1 and GLP‐2 also activate gluconeogenesis, but to a lesser degree than their piscine counterparts.
Mommsen, Thomas P., Andrews, P.C., Plisetskaya, Erika M.   +2 more
openaire   +2 more sources

Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation

Nature Communications, 2023
A large group of hormones are stored as amyloid fibrils in acidic secretion vesicles before they are released into the bloodstream and readopt their functional state.
Dániel Horváth, Zsolt Dürvanger, Dóra K. Menyhárd, Máté Sulyok-Eiler, Fruzsina Bencs, Gergő Gyulai, Péter Horváth, Nóra Taricska, András Perczel   +8 more
doaj   +1 more source

Effects of the vasoactive intestinal peptide (VIP) and related peptides on glioblastoma cell growth in vitro [PDF]

, 2003
The growth rate of numerous cancer cell lines is regulated in part by actions of neuropeptides of the vasoactive intestinal peptide (VIP) family, which also includes pituitary adenylate cyclase-activating peptide (PACAP), glucagon, and peptide histidine ...
Alleaume, Céline, Dufès, Christine, Montoni, Alicia, Muller, Jean-Marc, Olivier, Jean-Christophe   +4 more
core   +1 more source

The sleeping beauty: how reproductive diapause affects hormone signaling, metabolism, immune response and somatic maintenance in Drosophila melanogaster. [PDF]

PLoS ONE, 2014
Some organisms can adapt to seasonal and other environmental challenges by entering a state of dormancy, diapause. Thus, insects exposed to decreased temperature and short photoperiod enter a state of arrested development, lowered metabolism, and ...
Olga I Kubrak, Lucie Kučerová, Ulrich Theopold, Dick R Nässel   +3 more
doaj   +1 more source

What doesn't kill you makes you stranger: Dipeptidyl peptidase-4 (CD26) proteolysis differentially modulates the activity of many peptide hormones and cytokines generating novel cryptic bioactive ligands [PDF]

, 2019
Dipeptidyl peptidase 4 (DPP4) is an exopeptidase found either on cell surfaces where it is highly regulated in terms of its expression and surface availability (CD26) or in a free/circulating soluble constitutively available and intrinsically active form.
Aguilar-Pérez, Alexandra, Awad, Mohamed E., Eisa, Nada H., Elmansi, Ahmed M., Fulzele, Sadanand, Hamrick, Mark W., Herberg, Samuel, Hill, William D., Hussein, Khaled A., Isales, Carlos M., Kondrikov, Dmitry, McGee-Lawrence, Meghan E., Periyasamy-Thandavan, Sudharsan, Volkman, Brian F.   +13 more
core   +1 more source

How glucagon-like is glucagon-like peptide-1? [PDF]

Diabetologia, 1984
Although glucagon-like peptide-1 has the appearance of a glucagon-homologue that may be co-secreted with glucagon, synthetic glucagon-like peptide-1-(1-37) does not significantly affect plasma glucose and insulin concentrations when administered at high doses (100 and 400 micrograms) to cortisone-pretreated rabbits.
M, Ghiglione, L O, Uttenthal, S K, George, S R, Bloom   +3 more
openaire   +2 more sources

Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain. [PDF]

, 2015
© 2015 The Authors.Objective: Although Glucagon-like peptide 1 is a key regulator of energy metabolism and food intake, the precise location of GLP-1 receptors and the physiological relevance of certain populations is debatable.
Cork, SC, Gribble, FM, Holt, MK, Reimann, F, Richards, JE, Trapp, S   +5 more
core   +2 more sources

A new family of diverse skin peptides from the microhylid frog genus phrynomantis [PDF]

, 2020
A wide range of frogs produce skin poisons composed of bioactive peptides for defence against pathogens, parasites and predators. While several frog families have been thoroughly screened for skin-secreted peptides, others, like the Microhylidae, have ...
Ballet, Steven, Martel, An, Martin, Charlotte, Pasmans, Frank, Raaymakers, Constantijn, Roelants, Kim, Stijlemans, Benoit, Zaman, Shabnam   +7 more
core   +1 more source