Results 1 to 10 of about 195,219 (266)

SIRT1: potential target in glucocorticoid-resistant diseases [PDF]

Frontiers in Immunology
Glucocorticoid resistance is a challenging problem in clinical practice. Increasing glucocorticoid sensitivity and reducing resistance are important in the management of certain diseases.
Jun Xie, Siyi Che, Jiao Liu, Xiaoru Long
doaj   +2 more sources

Burden of Glucocorticoid Use and Risk of Toxicities Among Patients with Immunoglobulin-G4-Related Disease: A Retrospective US-Based Claims Study [PDF]

Rheumatology and Therapy
Introduction Glucocorticoids are commonly used to treat immunoglobulin G4-related disease (IgG4-RD), but there is limited real-world evidence describing glucocorticoid-related toxicities in this population.
Zachary S. Wallace, Jenny Y. Park, Elizabeth Serra, Patrick Gagnon-Sanschagrin, Annie Guérin, Kristina Patterson, Haridarshan Patel, Vikesh K. Singh   +7 more
doaj   +2 more sources

Hypoglycaemia in adrenal insufficiency

Frontiers in Endocrinology, 2023
Adrenal insufficiency encompasses a group of congenital and acquired disorders that lead to inadequate steroid production by the adrenal glands, mainly glucocorticoids, mineralocorticoids and androgens.
Shien Chen Lee, Elizabeth S. Baranowski, Rajesh Sakremath, Vrinda Saraff, Vrinda Saraff, Zainaba Mohamed, Zainaba Mohamed   +6 more
doaj   +1 more source

The Negative Effect of Protein Phosphatase Z1 Deletion on the Oxidative Stress Tolerance of Candida albicans Is Synergistic with Betamethasone Exposure

Journal of Fungi, 2021
The glucocorticoid betamethasone (BM) has potent anti-inflammatory and immunosuppressive effects; however, it increases the susceptibility of patients to superficial Candida infections.
Ágnes Jakab, Tamás Emri, Kinga Csillag, Anita Szabó, Fruzsina Nagy, Edina Baranyai, Zsófi Sajtos, Dóra Géczi, Károly Antal, Renátó Kovács, Krisztina Szabó, Viktor Dombrádi, István Pócsi   +12 more
doaj   +1 more source

Tart Cherry (Fruit of Prunus cerasus) Concentrated Powder (TCcp) Ameliorates Glucocorticoid-Induced Muscular Atrophy in Mice

Medicina, 2021
Background and Objectives: The present study investigated the beneficial effects of tart cherry (fruit of Prunus cerasus) concentrated powder (TCcp) on glucocorticoid (GLU)-induced catabolic muscular atrophy in the skeletal muscle of mice.
Sae-Kwang Ku, Jong-Min Lim, Hyung-Rae Cho, Khawaja Muhammad Imran Bashir, Young Suk Kim, Jae-Suk Choi   +5 more
doaj   +1 more source

Case Report: Real NPSLE? A patient with systemic sclerosis overlapping systemic lupus erythematosus presenting as epilepsy

Frontiers in Immunology, 2023
Neuropsychiatric systemic lupus erythematosus (NPSLE) is the diagnosis that rheumatologists most often need to consider when a patient with lupus presents with neurologic symptoms.
Jialin Zhang, Jialin Zhang, Xiaodong Wu, Jing Xue, Lei Liu   +4 more
doaj   +1 more source

Glucocorticoids in rheumatoid arthritis: current status and future studies

RMD Open, 2020
Since their first use for treating rheumatoid arthritis (RA) in the late 1940s, glucocorticoids (GCs) have been representing a substantial part of the therapeutic arsenal for RA.
Frank Buttgereit, Charlotte Hua, Bernard Combe   +2 more
doaj   +1 more source

Expression of long noncoding RNA Xist is induced by glucocorticoids

Frontiers in Endocrinology, 2022
Glucocorticoids (GCs) are potent anti-inflammatory and immunosuppressive agents. However, their clinical usage is limited by severe multisystemic side effects.
Yun Su, Xing Chen, Hongyan Zhou, Hongyan Zhou, Sean Shaw, Jie Chen, Carlos M. Isales, Carlos M. Isales, Jing Zhao, Xingming Shi, Xingming Shi   +10 more
doaj   +1 more source

Acinetobacter baumannii among Patients Receiving Glucocorticoid Aerosol Therapy during Invasive Mechanical Ventilation, China

Emerging Infectious Diseases, 2022
Acinetobacter baumannii is a nosocomial pathogen associated with severe illness and death. Glucocorticoid aerosol is a common inhalation therapy in patients receiving invasive mechanical ventilation.
Wenchao Zhang, Mei Yin, Wei Li, Nana Xu, Haining Lu, Weidong Qin, Hui Han, Chen Li, Dawei Wu, Hao Wang   +9 more
doaj   +1 more source

Network Meta-Analysis of Different Intravenous Glucocorticoid Regimes for the Treatment of Graves’ Orbitopathy

Frontiers in Pharmacology, 2022
Background: Intravenous glucocorticoid (GC) has been proposed to treat moderately severe Graves’ orbitopathy (GO); however, the optimal regime remains debatable.
Jun Jia, Jingjian Dong, Lin Deng
doaj   +1 more source