Burden of Glucocorticoid Use and Risk of Toxicities Among Patients with Immunoglobulin-G4-Related Disease: A Retrospective US-Based Claims Study [PDF]
Rheumatology and TherapyIntroduction Glucocorticoids are commonly used to treat immunoglobulin G4-related disease (IgG4-RD), but there is limited real-world evidence describing glucocorticoid-related toxicities in this population.
Zachary S. Wallace +7 more
doaj +2 more sources
Effect of Preoperative Nebulised Dexamethasone and Nebulised Magnesium Sulphate on Postoperative Sore Throat in Prone Position Surgeries- A Randomised Double-Blind Study [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Postoperative Sore Throat (POST) is a frequently encountered complication after general anaesthesia with tracheal intubation and positional changes.
G Manuj kumar +6 more
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EFFECTS OF DRUG BETAMETHASONE ON HEMATOLOGICAL PARAMETERS OF RATTUS NORVEGICUS (BERKENHOUT 1769) IN VIVO CONDITIONS [PDF]
Journal of IMAB, 2022 Glucocorticoids prevent or suppress the full inflammatory response to the infectious, immunological or physical agents by inhibiting early inflammatory events such as edema or cell exudation. The main effect of glucocorticoids on the inflammatory process
Edhem Hasković +5 more
doaj +1 more source
International Journal of Molecular Sciences, 2022 Osteoporosis is a serious health issue among aging postmenopausal women. The majority of postmenopausal women with osteoporosis have bone loss related to estrogen deficiency. The rapid bone loss results from an increase in bone turnover with an imbalance
Chui H Cheng, Li-Ru Chen, Kuo-Hu Chen
semanticscholar +1 more source
Frontiers in Behavioral Neuroscience, 2021 The hypothalamic-pituitary-adrenal axis is a complex system of neuroendocrine pathways and feedback loops that function to maintain physiological homeostasis.
Julietta A. Sheng +7 more
doaj +1 more source
Fresh insights into glucocorticoid-induced diabetes mellitus and new therapeutic directions
Nature Reviews Endocrinology, 2022 Glucocorticoid hormones were discovered to have use as potent anti-inflammatory and immunosuppressive therapeutics in the 1940s and their continued use and development have successfully revolutionized the management of acute and chronic inflammatory ...
Jiaxue Li, C. Cummins
semanticscholar +1 more source
Ruxolitinib for Glucocorticoid-Refractory Chronic Graft-versus-Host Disease.
New England Journal of Medicine, 2021 BACKGROUND Chronic graft-versus-host disease (GVHD), a major complication of allogeneic stem-cell transplantation, becomes glucocorticoid-refractory or glucocorticoid-dependent in approximately 50% of patients. Robust data from phase 3 randomized studies
R. Zeiser +15 more
semanticscholar +1 more source
Glucocorticoids in rheumatoid arthritis: current status and future studies
RMD Open, 2020 Since their first use for treating rheumatoid arthritis (RA) in the late 1940s, glucocorticoids (GCs) have been representing a substantial part of the therapeutic arsenal for RA.
Frank Buttgereit +2 more
doaj +1 more source
Clinical observations of acute onset of myopic optic neuropathy in a real-world setting [PDF]
International Journal of Ophthalmology, 2021 AIM: To describe the clinical features of acute myopic onset of optic neuropathy and observe the effects of retrobulbar and systemic glucocorticoid therapy in a real-world setting.
Li Liao +3 more
doaj +1 more source
Frontiers in Physiology, 2022 Cortisol is a robust circadian signal that synchronises peripheral circadian clocks with the central clock in the suprachiasmatic nucleus via glucocorticoid receptors that regulate peripheral gene expression.
Simon N. Archer +4 more
doaj +1 more source