Results 21 to 30 of about 195,219 (266)
Aims Chronic stress and glucocorticoid exposure are risk factors for depression. Oxytocin (OT) has been shown to have antistress and antidepressant‐like effects in male rodents.
Masayoshi Mori+7 more
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Case Report: A Rare Case of Pembrolizumab-Induced Bullous Pemphigoid
The programmed cell death protein 1 inhibitor pembrolizumab, an immune checkpoint inhibitor, has subsequently been approved for the treatment of a wide variety of malignant tumors. Compared with conventional chemotherapy, immunotherapy is associated with
Xiaoyan Zhang+4 more
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Objective: Herein, we aimed to determine the clinical efficacy of recombinant human thrombopoietin (rhTPO) combined with glucocorticoids for treating immune thrombocytopenia (ITP).Methods: Clinical data of 87 patients with ITP admitted to our hospital ...
Jing-xin Zhou+8 more
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Control of Leukocyte Trafficking by Stress-Associated Hormones
Leukocyte migration is a crucial process in both homeostatic and inflammatory conditions. The spatiotemporal distribution of immune cells is balanced between processes of cellular mobilization into the bloodstream, their adhesion to vascular beds and ...
Louise M. Ince+4 more
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Background: Corneal infection of Colletotrichum gloeosporioides is uncommon and usually limited to the anterior stroma. However, we observed a case of corneal stromal perforation caused by this fungus under a compromised condition.
Kazuki Imai+7 more
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ObjectiveTo investigate the clinical efficacy and prognostic factors of transnasal endoscopic optic decompression in the treatment of traumatic optic neuropathy (TON).MethodsA retrospective analysis was performed on 13 TON patients in The Seventh ...
Xiang Tu+7 more
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Stress, Allostatic Load, and Psychosis: One Step Forward in Research But Where to Go Next?
Stress exposure leads to the activation of several biological mechanisms that have been termed allostasis. These processes enable adaptation to novel situations; however; their prolonged activation exerts systemic and detrimental effects called the ...
Błażej Misiak
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Introduction and purpose: Primary adrenal insufficiency can result from diseases affecting the adrenal glands, while secondary adrenal insufficiency is caused by suppression of the hypothalamic-pituitary-adrenal axis.
Aleksandra Kiełczewska+2 more
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The Effect of Chronic Glucocorticoid Exposure on Brown Adipose Tissue in Cushing’s Disease
Aim:In this study, we aimed to evaluate the levels of brown adipose tissue markers uncoupling protein-1 (UCP-1), irisin, bone morphogenetic protein-7 (BMP-7) and PR-Domain Zinc Finger Protein-16 (PRDM-16) in Cushing’s disease (CH) with hypercortisolism ...
Alev Selek+7 more
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HIF-1α Regulates Glucocorticoid-Induced Osteoporosis Through PDK1/AKT/mTOR Signaling Pathway
Long-term and high dose glucocorticoid treatment can cause decreased viability and function of osteoblasts, which leads to osteoporosis and osteonecrosis. In this study, we investigated the role and mechanism of action of HIF-1α in glucocorticoid-induced
Wen-Ning Xu+4 more
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