Results 21 to 30 of about 254,141 (317)

The Protective Role of Alpha-Ketoglutaric Acid on the Growth and Bone Development of Experimentally Induced Perinatal Growth-Retarded Piglets

Animals, 2021
The effect of alpha-ketoglutaric acid (AKG) supplementation to experimentally-induced, perinatal growth-retarded piglets was examined. Sows were treated with a synthetic glucocorticoid (Gc) during the last 25 days of pregnancy, and after the birth ...
Ewa Tomaszewska, Natalia Burmańczuk, Piotr Dobrowolski, Małgorzata Świątkiewicz, Janine Donaldson, Artur Burmańczuk, Maria Mielnik-Błaszczak, Damian Kuc, Szymon Milewski, Siemowit Muszyński   +9 more
doaj   +1 more source

Uric Acid and Cortisol Levels in Plasma Correlate with Pre-Competition Anxiety in Novice Athletes of Combat Sports

Brain Sciences, 2022
Pre-competition anxiety is very prevalent in novice athletes, causing stress and drastic decreases in their performances. Cortisol plays a central role in the psychosomatic responses to stress and also in the physiology of strenuous exercise.
Luis Fernando Garcia de Oliveira, Tácito Pessoa Souza-Junior, Juliane Jellmayer Fechio, José Alberto Fernandes Gomes-Santos, Ricardo Camões Sampaio, Cristina Vasconcelos Vardaris, Rafael Herling Lambertucci, Marcelo Paes de Barros   +7 more
doaj   +1 more source

Diagnosis and approach to glucocorticoid-induced adrenal insufficiency and glucocorticoid withdrawal syndrome

Journal of Education, Health and Sport
Introduction and purpose: Primary adrenal insufficiency can result from diseases affecting the adrenal glands, while secondary adrenal insufficiency is caused by suppression of the hypothalamic-pituitary-adrenal axis.
Aleksandra Kiełczewska, Grzegorz Szcześniak, Anna Kiełczewska   +2 more
doaj   +1 more source

Effects of Glucocorticoid Therapy on Sepsis Depend Both on the Dose of Steroids and on the Severity and Phase of the Animal Sepsis Model

Life, 2022
Steroids are currently being used in sepsis, particularly in septic shock. However, clinical trials to date have shown contradictory results. This could be attributed to the different patient endotypes and steroid doses, which have also contributed to ...
Ye Jin Park, Min Ji Lee, Jinkun Bae, Jung Ho Lee, Han A Reum Lee, Sehwan Mun, Yun-seok Kim, Chang June Yune, Tae Nyoung Chung, Kyuseok Kim   +9 more
doaj   +1 more source

Aurora Kinase A Regulates Cell Transitions in Glucocorticoid-Induced Bone Loss

Cells, 2023
Glucocorticoid-induced bone loss is a severe and toxic effect of long-term therapy with glucocorticoids, which are currently prescribed for millions of people worldwide.
Xiaojing Qiao, Yang Yang, Yan Zhao, Xiuju Wu, Li Zhang, Xinjiang Cai, Jaden Ji, Kristina I. Boström, Yucheng Yao   +8 more
doaj   +1 more source

Polarization Behavior of Bone Macrophage as Well as Associated Osteoimmunity in Glucocorticoid-Induced Osteonecrosis of the Femoral Head

Journal of Inflammation Research, 2023
Qingyu Zhang,1 Wei Sun,2,3 Tengqi Li,4,5 Fanxiao Liu1 1Department of Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, People’s Republic of China; 2Department of Orthopaedic Surgery, Perelman ...
Zhang Q, Sun W, Li T, Liu F
doaj  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Burden of Glucocorticoid Use and Risk of Toxicities Among Patients with Immunoglobulin-G4-Related Disease: A Retrospective US-Based Claims Study

Rheumatology and Therapy
Introduction Glucocorticoids are commonly used to treat immunoglobulin G4-related disease (IgG4-RD), but there is limited real-world evidence describing glucocorticoid-related toxicities in this population.
Zachary S. Wallace, Jenny Y. Park, Elizabeth Serra, Patrick Gagnon-Sanschagrin, Annie Guérin, Kristina Patterson, Haridarshan Patel, Vikesh K. Singh   +7 more
doaj   +1 more source

Increased Chondroprotective Effect of Combining Hyaluronic Acid with a Glucocorticoid Compared to Separate Administration on Cytokine-Treated Osteoarthritic Chondrocytes in a 2D Culture

Biomedicines, 2022
Intra-articular injections of glucocorticoids (GC) or hyaluronic acid (HA) are commonly used interventions for patients suffering from knee osteoarthritis (OA).
Christoph Bauer, Lukas B. Moser, Vivek Jeyakumar, Eugenia Niculescu-Morzsa, Daniela Kern, Stefan Nehrer   +5 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source