Results 231 to 240 of about 2,551,103 (363)

Minireview: new molecular mediators of glucocorticoid receptor activity in metabolic tissues.

open access: yesMolecular Endocrinology, 2014
Rucha A Patel   +2 more
semanticscholar   +1 more source

AZD0449, an inhaled JAK1 inhibitor, in healthy participants and patients with mild asthma

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Inhaled corticosteroids (ICS) plus bronchodilator are recommended for the treatment of asthma. Targeting the JAK1‐dependent pathway may be an alternative for asthma management in patients with incomplete response to ICS. The aim of this study was to investigate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of AZD0449, a
Anna Lundahl   +11 more
wiley   +1 more source

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor.

open access: yesImmunity, 2002
R. McHugh   +6 more
semanticscholar   +1 more source

Engineering antibodies with cancer‐associated binding sites

open access: yesBMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian   +4 more
wiley   +1 more source

Characterization of wild type and mutant glucocorticoid receptors from rat hepatoma and mouse lymphoma cells.

open access: hybrid, 1985
Jeffrey P. Northrop   +3 more
openalex   +1 more source

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