Immune Checkpoint Inhibitors and Cardiovascular Adverse Events
Abstract In the last years, we assisted to a tremendous increase in therapeutic options for the management of cancers, with immunotherapy at the forefront of this innovation. Immune checkpoint inhibitors (ICIs) have been developed to enhance the activity of the immune system against cancer cells (1) and the number of approvals for ICIs has rapidly ...
Maria Luisa De Perna+4 more
wiley +1 more source
Glucocorticoid receptor inhibits Th2 immune responses by down-regulating Pparg and Gata3 in schistosomiasis. [PDF]
Sun T+8 more
europepmc +1 more source
Neutrophil elastase produces 52-kD and 30-kD glucocorticoid receptor fragments in the cytosol of human leukemia cells [PDF]
CW Distelhorst+4 more
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Asoprisnil as a Novel Ligand Interacting with Stress-Associated Glucocorticoid Receptor. [PDF]
Ejiohuo O+3 more
europepmc +1 more source
The endogenous heat-stable glucocorticoid receptor stabilizing factor and the H-2 locus [PDF]
Karen L. Leach+2 more
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Skeletal muscle and subcutaneous fat quantity as prognostic indicators in cardiac amyloidosis
Aims Disease‐related changes in body composition are associated with worse outcomes in chronic heart failure. In cardiac amyloidosis (CA), the prognostic value of direct body composition measures is understudied. Methods and results We identified 160 consecutive patients with CA (transthyretin [ATTR] or light chain [AL]) diagnosed between 2001 and 2021
Joshua Longinow+4 more
wiley +1 more source
Role of glucocorticoid receptor expression in Chronic Chagas Cardiomyopathy: implications for inflammation and cardiac hypertrophy. [PDF]
González FB+10 more
europepmc +1 more source
Stable Overproduction of Intact Glucocorticoid Receptors in Mammalian Cells Using a Selectable Glucocorticoid Responsive Dihydrofolate Reductase Gene [PDF]
Deborah L. Bellingham, John A. Cidlowski
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