Results 241 to 250 of about 2,524,396 (364)

Oral Glucocorticoid–Sparing Effect of Benralizumab in Severe Asthma

New England Journal of Medicine, 2017
Parameswaran Nair, S. Wenzel, K. Rabe, A. Bourdin, N. Lugogo, P. Kuna, P. Barker, Stephanie Sproule, S. Ponnarambil, M. Goldman   +9 more
semanticscholar   +1 more source

Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: the Randomized, Phase 3, TULIP‐SC Study

Arthritis &Rheumatology, Accepted Article.
Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate‐to‐severe SLE activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly for 52 weeks (1:1 ...
Susan Manzi, Ian N. Bruce, Eric F. Morand, Richard Furie, Yoshiya Tanaka, Kenneth C. Kalunian, Anca Askanase, Patricia Puzio, Emon Khan, Jenny Wissmar, Michael Song, Catharina Lindholm, The TULIP‐SC investigators   +12 more
wiley   +1 more source

Review for "Molecular cloning, characterization, and gene expression behavior of glucocorticoid and mineralocorticoid receptors from the Chinese alligator ( <i>Alligator sinensis</i> )"

, 2020
Mary E. White
openalex   +1 more source

New insights into the anti-inflammatory mechanisms of glucocorticoids: an emerging role for glucocorticoid-receptor-mediated transactivation.

Endocrinology, 2013
Sofie Vandevyver, L. Dejager, J. Tuckermann, C. Libert   +3 more
semanticscholar   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists, Sodium‐Glucose Cotransporter‐2 Inhibitors, and Risk of Autoimmune Rheumatic Diseases

Arthritis &Rheumatology, Accepted Article.
Objective GLP‐1 receptor agonists (GLP‐1RAs) and SGLT2 inhibitors (SGLT2is) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear. We compared ARD incidence following initiation of GLP‐1RAs, or SGLT2is, vs.
Derin Karacabeyli, Diane Lacaille, Na Lu, Hui Xie, J. Antonio Aviña‐Zubieta   +4 more
wiley   +1 more source

Data mining historical Chinese medical recipe collections and nuclear receptor profiling identify plant fractions that modulate glucocorticoid receptor activity. [PDF]

Front Pharmacol
Prackwieser J, Houtman R, Kievits T, Melchers D, Guan H, Seifert G, Konietschke F, Lamottke K, Unschuld PU, Kirk N.   +9 more
europepmc   +1 more source

Glucocorticoid regulation of inflammation and its functional correlates: from HPA axis to glucocorticoid receptor dysfunction

Annals of the New York Academy of Sciences, 2012
M. Silverman, E. Sternberg
semanticscholar   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

Impact of glucocorticoid receptor polymorphism rs6198 on sepsis survival in a prospective multicenter cohort. [PDF]

Sci Rep
Sombetzki C, Palmowski L, Ziehe D, Nowak H, Rahmel T, Ehrentraut SF, Thon P, Orlowski J, Bergmann L, Adamzik M, Koos B, Rump K, SepsisDataNet.NRW research group.   +12 more
europepmc   +1 more source

Glucocorticoid receptors

Japanese Journal of Pharmacology, 1978
openaire   +1 more source