Results 41 to 50 of about 91,017 (115)

The glucocorticoid-Angptl4-ceramide axis induces insulin resistance through PP2A and PKCζ. [PDF]

, 2017
Chronic glucocorticoid exposure is associated with the development of insulin resistance. We showed that glucocorticoid-induced insulin resistance was attenuated upon ablation of Angptl4, a glucocorticoid target gene encoding the secreted protein ...
Benjamin, Daniel I, Chen, Tzu-Chieh, Costello, Damian E, Kuo, Taiyi, Lee, Rebecca A, Li, Mei-Lan, Mar, Darryl J, Nomura, Daniel K, Wang, Jen-Chywan   +8 more
core   +1 more source

Glucocorticoids rapidly inhibit oxytocin-stimulated adrenocorticotropin release from rat anterior pituitary cells, without modifying intracellular calcium transients [PDF]

, 1993
Glucocorticoid hormones suppress the secretion of ACTH evoked by secretagogues such as CRF and arginine vasopressin. In this study, we investigated the effects of glucocorticoids on ACTH release induced by oxytocin (OT) and on intracellular free calcium ...
Dayanithi, G., Gratzl, Manfred, Link, H.
core   +1 more source

The melanocortin receptors and their accessory proteins. [PDF]

, 2013
The five melanocortin receptors (MCRs) named MC1R-MC5R have diverse physiological roles encompassing pigmentation, steroidogenesis, energy homeostasis and feeding behavior as well as exocrine function.
Chan, LF, Clark, AJ, Gorrigan, RJ, Ramachandrappa, S   +3 more
core   +2 more sources

Rationale for Prolonged Glucocorticoid Use in Pediatric ARDS: What the Adults Can Teach Us. [PDF]

, 2016
Based on molecular mechanisms and physiologic data, a strong association has been established between dysregulated systemic inflammation and progression of acute respiratory distress syndrome (ARDS).
Meduri, Gianfranco Umberto, Schwingshackl, Andreas   +1 more
core   +1 more source

Mechanism of glucocorticoid receptor down-regulation by glucocorticoids.

Journal of Biological Chemistry, 1988
The effect of glucocorticoids on the regulation of glucocorticoid receptor mRNA was studied in two different cell lines, human IM-9 lymphocytes and rat pancreatic acinar AR42J cells. Using a glucocorticoid receptor cDNA probe, glucocorticoid receptor mRNA was examined by Northern blot hybridization and quantitated by slot-blot hybridization.
Ira D. Goldfine, S Rosewicz, Roger L. Miesfeld, Alexander R McDonald, Craig D. Logsdon, Betty A. Maddux   +5 more
openaire   +3 more sources

Glucocorticoid receptor gene inactivation in dopamine-innervated areas selectively decreases behavioral responses to amphetamine [PDF]

, 2014
Peer reviewedPublisher ...
Anne-Sophie eDelbes, Celine eCansell, Francois eTronche, Frederic eAmbroggi, Frederic eAmbroggi, Jacques eBARIK, Jacques eBARIK, Marc eTuriault, Marie-Louise eDongelmans, Pier Vincenzo Piazza, Sebastien eParnaudeau, Sebastien eParnaudeau, Serge H Luquet   +12 more
core   +6 more sources

Live Cell Imaging Unveils Multiple Domain Requirements for In Vivo Dimerization of the Glucocorticoid Receptor [PDF]

, 2014
Glucocorticoids are essential for life, but are also implicated in disease pathogenesis and may produce unwanted effects when given in high doses.
Alvarez, Lautaro Damian, Ashwell, Jonathan D., Burton, Gerardo, Ganesan, Sundar, Grøntved, Lars, Hager, Gordon L., Johnson, Thomas A., Levi, Valeria, Mittelstadt, Paul R., Ogara, Maria Florencia, Pecci, Adali, Pooley, John R., Presman, Diego Martin, Schiltz, R. Louis, Stortz, Martin Dario   +14 more
core   +3 more sources

Allosteric Modulators of Steroid Hormone Receptors : Structural Dynamics and Gene Regulation [PDF]

, 2012
Peer reviewedPublisher ...
Acevedo, Almlöf, Almlöf, Almlöf, Andersen, Babu, Bain, Ball, Barkhem, Baskakov, Beck, Benecke, Berry, Betney, Bevan, Bhasin, Billon-Galés, Bledsoe, Blind, Bolton, Boonyaratanakornkit, Briet, Brodie, Brzozowski, Bulynko, Börjesson, Callewaert, Carlstedt-Duke, Carlstedt-Duke, Carroll, Carroll, Centenera, Chamberlain, Chandra, Chang, Chen, Chen, Chen, Claessens, Conneely, Connell, Cutress, Cutress, Dahlman-Wright, Dahlman-Wright, Dahlman-Wright, Daniel, Darimont, Davies, Demarest, Doesburg, Dong, Dubbink, Duma, Dunker, Dunker, Dunker, Dyson, Dziedzic-Letka, Egea, Eick, Eisenhaber, Escriva, Estébanez-Perpiñá, Evans, Faus, Fawell, Ferreira, Fischer, Freeman, Fu, Fu, Fu, Funder, Fuse, Garza, Garza, Gaughan, Gellersen, Georgiakaki, Glass, Govindan, Green, Green, Green, Greene, Groeneweg, Gronemeyer, He, He, He, He, Heery, Hermann, Hill, Hilser, Hollenberg, Hollenberg, Holthauzen, Huang, Hur, Härd, Iain J. McEwan, Iakoucheva, Iakoucheva, Iñiguez-Lluhí, Jeltsch, Jenster, Joerger, Jones, Kaul, Khan, Khan, Kininis, Kjaergaard, Ko, Konduri, Kornberg, Krasowski, Kraus, Kulkarni, Kumar, Kumar, Kumar, Kumar, Kumar, Kumar, Kumar, Kumar, Kumar, Kumar, Kumar, Kumar, Langley, Langley, Lanz, Lavery, Lavery, Lavery, Lefstin, Linding, Liu, Loven, Lubahn, Malik, Mao, Mao, Massie, McDonnell, McDonnell, McEwan, McEwan, McEwan, McEwan, McEwan, McEwen, McInerney, McKenna, McNally, Meijsing, Metzger, Midic, Miller, Mérot, Métivier, Nagaich, Nagy, Nettles, Nilsson, Nocula-£ugowska, Oakley, Oldfield, Onate, Paige, Picard, Pike, Pippal, Powell, Pratt, Prilusky, Putcha, Raj Kumar, Rajagopalan, Rayasam, Reid, Reid, Ricketson, Rochel, Roeder, Roemer, Rogatsky, Rogatsky, Rosenfeld, Savory, Schoenmakers, Schwabe, Schwabe, Shaffer, Shatkina, Shen, Shoemaker, Simental, Smith, Smith, So, So, Spillman, Stanisiæ, Stenoien, Street, Sugase, Surjit, Takimoto, Tanner, Tetel, Timasheff, Tompa, Tora, Tremblay, Tzukerman, Umetani, Uversky, Uversky, Vacic, van Royen, Verkhivker, Vicent, Wang, Wang, Wang, Wang, Wardell, Wardell, Wardell, Weigel, Weinberger, Wijayaratne, Wood, Wood, Wrange, Wright, Wärnmark, Xu, Yang, Yang, Yang, Yoon, Zennaro, Zhang, Zhao, Zilliacus, Zor   +251 more
core   +1 more source

Expression of SMARCD1 interacts with age in association with asthma control on inhaled corticosteroid therapy. [PDF]

, 2020
BackgroundGlobal gene expression levels are known to be highly dependent upon gross demographic features including age, yet identification of age-related genomic indicators has yet to be comprehensively undertaken in a disease and treatment-specific ...
Burchard, Esteban G, Croteau-Chonka, Damien C, Dahlin, Amber, Eng, Celeste, Kelly, Rachel, Kho, Alvin T, Lu, Quan, Lutz, Sharon M, Mak, Angel CY, McGeachie, Michael J, Oh, Sam S, Panganiban, Ronald, Raby, Benjamin A, Rodriguez-Santana, Jose R, Saef, Benjamin, Sajuthi, Satria, Seibold, Max A, Sordillo, Joanne E, Tantisira, Kelan G, Urbanek, Cydney, Wang, Alberta L, Weiss, Scott T, Wu, Ann Chen   +22 more
core   +1 more source

Ozone Inhalation Attenuated the Effects of Budesonide on Aspergillus fumigatus-Induced Airway Inflammation and Hyperreactivity in Mice. [PDF]

, 2019
Inhaled glucocorticoids form the mainstay of asthma treatment because of their anti-inflammatory effects in the lung. Exposure to the air pollutant ozone (O3) exacerbates chronic airways disease.
Flayer, Cameron H, Ge, Moyar Q, Haczku, Angela, Hwang, Jin W, Jiang, Zhilong, Kokalari, Blerina, Redai, Imre G   +6 more
core