Molecules, 2023 Glucocorticoids are classified in section S9 of the Prohibited List of the World Anti-Doping Agency, due to a potential risk to improving physical performance and causing harm to the health of athletes.
Yuqi Ge +3 more
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Frontiers in Medicine, 2022 Glucocorticoids are commonly used to treat anti-GBM crescentic glomerulonephritis, however, the mechanism underlying its therapeutic effectiveness is not completely understood.
Xiaomei Wu +8 more
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Association between perioperative glucocorticoids and cancer metastasis and survival in patients undergoing radical cystectomy for urothelial carcinoma of the bladder: A single-center retrospective study [PDF]
Investigative and Clinical Urology, 2020 Purpose: Perioperative glucocorticoids have the potential to increase the risk of tumor metastasis. However, the relationship between perioperative glucocorticoids and oncologic outcomes remains controversial. The present study was undertaken to evaluate
Shiyu Mao +8 more
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The different roles of glucocorticoids in the hippocampus and hypothalamus in chronic stress-induced HPA axis hyperactivity. [PDF]
PLoS ONE, 2014 Hypothalamus-pituitary-adrenal (HPA) hyperactivity is observed in many patients suffering from depression and the mechanism underling the dysfunction of HPA axis is not well understood.
Li-Juan Zhu +11 more
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Metabolites, 2023 The main glucocorticoids involved in the stress response are cortisol and cortisone in most mammals and corticosterone in birds and rodents. Therefore, these analytes are currently the biomarkers more frequently used to evaluate the physiological ...
María Botía +6 more
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Confounding by indication probably distorts the relationship between steroid use and cardiovascular disease in rheumatoid arthritis: results from a prospective cohort study. [PDF]
PLoS ONE, 2014 OBJECTIVE: To evaluate the risk of cardiovascular disease in patients with rheumatoid arthritis exposed to glucocorticoids. METHODS: Retrospective analysis of exposure to glucocorticoids in a prospective cohort of 353 patients with rheumatoid arthritis ...
Alper M van Sijl +3 more
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Clinical evidence of an interferon–glucocorticoid therapeutic synergy in COVID-19
Signal Transduction and Targeted Therapy, 2021 Synthetic glucocorticoid dexamethasone is the first trial-proven drug that reduces COVID-19 mortality by suppressing immune system. In contrast, interferons are a crucial component of host antiviral immunity and can be directly suppressed by ...
Yingying Lu +11 more
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Glucocorticoids in Sepsis: To Be or Not to Be
Frontiers in Immunology, 2020 Sepsis is a highly lethal syndrome resulting from dysregulated immune and metabolic responses to infection, thereby compromising host homeostasis. Activation of the hypothalamic-pituitary-adrenal (HPA) axis and subsequently adrenocortical glucocorticoid (GC) production during sepsis are important regulatory processes to maintain homeostasis.
Jolien Vandewalle +3 more
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Intra-articular glucocorticoid injection site: best practice guidelines
Медицинский совет, 2021 The article presents modern recommendations for the use of systemic administration of glucocorticoids. It is indicated that there is a clear tendency to minimize the doses and timing of the appointment of systemic glucocorticoids in rheumatoid arthritis,
N. V. Chichasova, A. M. Lila
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Effects of different doses of glucocorticoids on postoperative atrial fibrillation: a meta-analysis
BMC Cardiovascular Disorders, 2023 Background Postoperative atrial fibrillation (POAF) is the most common arrhythmia after cardiac surgery, and its occurrence is closely related to inflammation. This paper intends to apply meta-analysis to investigate the effect of glucocorticoids on POAF.
Zhongzheng Zhou +3 more
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