Results 91 to 100 of about 415,196 (303)

Drug Use on Mont Blanc: A Study Using Automated Urine Collection [PDF]

open access: yes, 2016
Mont Blanc, the summit of Western Europe, is a popular but demanding high-altitude ascent. Drug use is thought to be widespread among climbers attempting this summit, not only to prevent altitude illnesses, but also to boost physical and/or psychological
Botre', Francesco   +10 more
core   +4 more sources

Regulation of CYP3A genes by glucocorticoids in human lung cells [v2; ref status: indexed, http://f1000r.es/1z6]

open access: yesF1000Research, 2013
Inhaled glucocorticoids are the first-line treatment for patients with persistent asthma.  However, approximately thirty percent of patients exhibit glucocorticoid insensitivity, which may involve excess metabolic clearance of the glucocorticoids by ...
Jessica K Roberts   +5 more
doaj   +1 more source

Critical roles of endogenous glucocorticoids for disease tolerance in malaria

open access: yes, 2019
During malaria, the hypothalamic-pituitary-adrenal (HPA) axis is activated and glucocorticoid (GC) levels are increased, but their essential roles have been largely overlooked.
De Bosscher, Karolien   +4 more
core   +1 more source

Cell-Type Specific Changes in Glial Morphology and Glucocorticoid Expression During Stress and Aging in the Medial Prefrontal Cortex. [PDF]

open access: yes, 2018
Repeated exposure to stressors is known to produce large-scale remodeling of neurons within the prefrontal cortex (PFC). Recent work suggests stress-related forms of structural plasticity can interact with aging to drive distinct patterns of pyramidal ...
Bruce S. McEwen   +8 more
core   +2 more sources

Common Infections in Patients Prescribed Systemic Glucocorticoids in Primary Care: A Population-Based Cohort Study

open access: yesPLoS Medicine, 2016
Background Little is known about the relative risk of common bacterial, viral, fungal, and parasitic infections in the general population of individuals exposed to systemic glucocorticoids, or about the impact of glucocorticoid exposure duration and ...
L. Fardet, I. Petersen, I. Nazareth
semanticscholar   +1 more source

Disease course, frequency of relapses and survival of 73 patients with juvenile or adult dermatomyositis [PDF]

open access: yes, 2005
Objective Our aim is to present the disease course, frequency of relapses and survival of juvenile and adult dermatomyositis (JDM/DM) patients. Methods Analysis was performed using data on 73 patients. The median follow-up for 38 JDM patients was
Balogh, Zsolt   +9 more
core  

Rheumatoid arthritis [PDF]

open access: yes, 2016
Rheumatoid arthritis is a chronic inflammatory joint disease, which can cause cartilage and bone damage as well as disability. Early diagnosis is key to optimal therapeutic success, particularly in patients with well-characterised risk factors for poor ...
Aletaha, Daniel   +2 more
core   +1 more source

Inhaled Glucocoriticoids in Children: A Facourable Therapeutic Index

open access: yesCanadian Respiratory Journal, 1999
In children with persistent asthma, inhaled glucocorticoids decrease symptoms and exacerbations, decrease the need for rescue bronchodilator medications, improve airway patency and reduce airway hyperresponsiveness.
F Estelle R Simons
doaj   +1 more source

Regulation of stem cell factor expression in inflammation and asthma

open access: yesMemorias do Instituto Oswaldo Cruz, 2005
Stem cell factor (SCF) is a major mast cell growth factor, which could be involved in the local increase of mast cell number in the asthmatic airways.
Carla A Da Silva, Nelly Frossard
doaj   +1 more source

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