Results 11 to 20 of about 288,891 (362)

Glucocorticoids in Sepsis: To Be or Not to Be

open access: yesFrontiers in Immunology, 2020
Sepsis is a highly lethal syndrome resulting from dysregulated immune and metabolic responses to infection, thereby compromising host homeostasis. Activation of the hypothalamic-pituitary-adrenal (HPA) axis and subsequently adrenocortical glucocorticoid (GC) production during sepsis are important regulatory processes to maintain homeostasis.
Jolien Vandewalle   +3 more
openaire   +4 more sources

Effects of different doses of glucocorticoids on postoperative atrial fibrillation: a meta-analysis

open access: yesBMC Cardiovascular Disorders, 2023
Background Postoperative atrial fibrillation (POAF) is the most common arrhythmia after cardiac surgery, and its occurrence is closely related to inflammation. This paper intends to apply meta-analysis to investigate the effect of glucocorticoids on POAF.
Zhongzheng Zhou   +3 more
doaj   +1 more source

Intra-articular glucocorticoid injection site: best practice guidelines

open access: yesМедицинский совет, 2021
The article presents modern recommendations for the use of systemic administration of glucocorticoids. It is indicated that there is a clear tendency to minimize the doses and timing of the appointment of systemic glucocorticoids in rheumatoid arthritis,
N. V. Chichasova, A. M. Lila
doaj   +1 more source

Glucocorticoid Receptor and Adipocyte Biology. [PDF]

open access: yes, 2018
Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during stress, such as fasting and starvation, in order to maintain plasma glucose levels.
Harris, Charles A   +2 more
core   +2 more sources

The Association Between Glucocorticoid Administration and the Risk of Impaired Efficacy of Axicabtagene Ciloleucel Treatment: A Systematic Review

open access: yesFrontiers in Immunology, 2021
BackgroundGlucocorticoid is one of the common and important strategies for the treatment of chimeric antigen receptor T (CAR-T) cell therapy-related toxicity.
Zhen Sun   +4 more
doaj   +1 more source

Glucocorticoids Inhibit Sodium Depletion-induced Salt Appetite in Rat [PDF]

open access: yes, 2010
Glucocorticoids, produced in adrenal cortex, exert potent natriuretic and diuretic actions in the kidney. Recently, it has been found that glucocorticoids could upregulate the expression of natriuretic peptide receptor A (NPR-A), the primary receptor of ...
Chao Liu   +3 more
core   +2 more sources

Glucocorticoids and lymphocytes. III. Effects of glucocorticoid administration on lymphocyte glucocorticoid receptors [PDF]

open access: yesBlood, 1983
Abstract To determine the effects of glucocorticoid administration on the number of measured lymphocyte glucocorticoid receptor sites and the duration of such effects, seven normal volunteers were studied. Glucocorticoid receptor levels of the lymphocytes circulating in the blood of each volunteer were determined. Glucocorticoid was then
Kendall A. Smith   +9 more
openaire   +4 more sources

Effects of intrauterine exposure to synthetic glucocorticoids on fetal, newborn, and infant hypothalamic-pituitary-adrenal axis function in humans : a systematic review [PDF]

open access: yes, 2009
BACKGROUND: Synthetic glucocorticoids are commonly used in reproductive medicine. Fetal organ systems are highly sensitive to changes in the intrauterine environment, including overexposure to glucocorticoids.
1994 Effect of corticosteroids for fetal maturation on perinatal outcomes   +257 more
core   +2 more sources

Pik3r1 Is Required for Glucocorticoid-Induced Perilipin 1 Phosphorylation in Lipid Droplet for Adipocyte Lipolysis. [PDF]

open access: yes, 2017
Glucocorticoids promote lipolysis in white adipose tissue (WAT) to adapt to energy demands under stress, whereas superfluous lipolysis causes metabolic disorders, including dyslipidemia and hepatic steatosis. Glucocorticoid-induced lipolysis requires the
Broughton, Augusta E   +6 more
core   +1 more source

Endogenous glucocorticoids in inflammation: contributions of systemic and local responses

open access: yesSwiss Medical Weekly, 2012
The anti-inflammatory actions of therapeutic glucocorticoids are well established and these drugs are widely used to treat a variety of inflammatory conditions.
Rowan S. Hardy   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy