Glucose-Dependent Insulinotropic Polypeptide [PDF]
Diabetes, 2011 OBJECTIVE To evaluate the glucose dependency of glucose-dependent insulinotropic polypeptide (GIP) effects on insulin and glucagon release in 10 healthy male subjects ([means ± SEM] aged 23 ± 1 years, BMI 23 ± 1 kg/m2,
Knop, Filip K +9 more
core +4 more sources
Cellular mechanisms governing glucose-dependent insulinotropic polypeptide secretion. [PDF]
Peptides, 2019 Glucose-dependent insulinotropic polypeptide (GIP) is a gut hormone secreted from the upper small intestine, which plays an important physiological role in the control of glucose metabolism through its incretin action to enhance glucose-dependent insulin
Moss, Catherine E. +3 more
core +7 more sources
Searching for the physiological role of glucose-dependent insulinotropic polypeptide [PDF]
Journal of Diabetes Investigation, 2016 Glucose-dependent insulinotropic polypeptide (GIP) was established as a gut hormone more than 40 years ago, and there is good experimental support for its role as an incretin hormone although deletion of the GIP receptor or the GIP cells or GIP receptor ...
Hartmann, Bolette +9 more
core +4 more sources
Increased glucose-dependent insulinotropic polypeptide (GIP) secretion in acromegaly [PDF]
European Journal of Endocrinology, 2001 Objective: Acromegaly is often associated with fasting and postprandial hyperinsulinemia, and the mechanisms involved are only partly understood. Hypersecretion of incretins such as glucose-dependent insulinotropic polypeptide (GIP) could play a role in ...
C. Gebbia +7 more
core +7 more sources
Cyclic AMP signalling in pancreatic islets [PDF]
, 2010 Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Pyne, Nigel J. +2 more
core +4 more sources
Gastric inhibitory polypeptide/glucose‐dependent insulinotropic polypeptide signaling in adipose tissue [PDF]
Journal of Diabetes Investigation, 2019 GIPR signaling in adipose tissue plays an important role in HFD-induced insulin resistance and hepatic steatosis in vivo, with no direct effect on fat accumulation, through IL-6 signaling.
Shunsuke Yamane, Norio Harada
doaj +3 more sources
Regulation of glucose and energy metabolism through actions of glucagon‐like peptide‐1 and glucose‐dependent insulinotropic polypeptide [PDF]
Journal of Diabetes InvestigationYasuo Zenimaru, Norio Harada
doaj +2 more sources
The interplay of glucose-dependent insulinotropic polypeptide in adipose tissue. [PDF]
J EndocrinolAdipose tissue was once known as a reservoir for energy storage but is now considered a crucial organ for hormone and energy flux with important effects on health and disease. Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone secreted from the small intestinal K cells, responsible for augmenting insulin release, and has gained ...
Kagdi S, Lyons SA, Beaudry JL.
europepmc +3 more sources
Glucose-Dependent Insulinotropic Polypeptide in Incretin Physiology: Role in Health and Disease
Endocrine ReviewsM Michael Wolfe, William W Chin
exaly +2 more sources
Glucose-Dependent Insulinotropic Polypeptide (GIP) Induces Calcitonin Gene-Related Peptide (CGRP)-I and Procalcitonin (Pro-CT) Production in Human Adipocytes [PDF]
, 2011 Context: Increased plasma levels of glucose-dependent insulinotropic polypeptide (GIP), calcitonin CT gene-related peptide (CGRP)-I, and procalcitonin (Pro-CT) are associated with obesity.
Beat Müller +21 more
core +1 more source