Results 91 to 100 of about 872,484 (256)
May growth lead to higher deprivation despite higher satisfaction ? [PDF]
In a relative deprivation framework, unless inequality is reduced, growth is associated with both higher satisfaction and higher deprivation. This may help explain the discontent with growth despite its benefits.
Wodon, Quentin, Yitzhaki, Shlomo
core
Social Deprivation and Digital Exclusion in England [PDF]
, 2008 Issues of digital exclusion are now increasingly considered alongside those of material deprivation when formulating interventions in neighbourhood renewal and other local policy interventions in health, policing and education.
Singleton, A, Longley, P
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Advanced Science, EarlyView.Hypoxia triggers a dual mechanism for BHLHE40 upregulation: reactive oxygen species (ROS)‐dependent post‐translational modification and hypoxia‐inducible factor (HIF)‐dependent transcriptional activation. Under hypoxic conditions, mitochondrial BHLHE40 accumulates and senses ROS via cysteine thiol oxidation and disulfide‐linked homodimer formation ...
Jia Liu +13 more
wiley +1 more source
Two classes of generalized deprivation indexes [PDF]
The paper uses two particular formulations of the Gini index to derive two different relative deprivation measures. We then generalize the formulation of these measures following Donaldson and Weymark (1980) and Berrebi and Silber (1985) and show how ...
Paolo Verme
core +2 more sources
Distributional change, reference groups and the measurement of relative deprivation [PDF]
This paper attempts to explicitly integrate the idea of reference group when measuring relative deprivation. It assumes that in assessing her situation in society an individual compares herself with individuals whose environment can be considered as ...
Jacques Silber, Paolo Verme
core +2 more sources
Advanced Science, EarlyView.This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang +10 more
wiley +1 more source
Neurobiology of Disease, 2004 The relationship between intracellular Ca2+ ([Ca2+]i) regulation and programmed cell death is not well-defined; both increases and decreases in [Ca2+]i have been observed in cells undergoing apoptosis.
Lorella M.T Canzoniero +6 more
doaj +1 more source
USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis
Advanced Science, EarlyView.This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui +5 more
wiley +1 more source
The Effects of Total Sleep Deprivation on Bayesian Updating [PDF]
Recent evidence suggests that nearly 25% of U.S. adults (47 million) suffer from some level of sleep deprivation. The impact of this sleep deprivation on the U.S. economy includes direct medical expenses related to sleep deprivation and related disorders,
Sean P.A. Drummond, David L. Dickinson
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Advanced Science, EarlyView.GC cells enhance glutamine accumulation by upregulating SLC1A5 expression. This upregulation not only boosts GC cell proliferation, but also outcompetes CD8+ T cells for glutamine and suppresses their antitumor immunity. Mechanistically, METTL7A deficiency in GC induces SLC1A5 overexpression via an m6A‐dependent pathway and N‐glycosylation ...
Mingjun Sun +16 more
wiley +1 more source