Glucose repression inSaccharomyces cerevisiae [PDF]
FEMS Yeast Research, 2015 Glucose is the primary source of energy for the budding yeast Saccharomyces cerevisiae. Although yeast cells can utilize a wide range of carbon sources, presence of glucose suppresses molecular activities involved in the use of alternate carbon sources as well as it represses respiration and gluconeogenesis.
Jens Nielsen
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The novel properties of Kluyveromyces marxianus glucose sensor/receptor repressor pathway and the construction of glucose repression-released strains [PDF]
Microbial Cell Factories, 2023 Background Glucose repression in yeast leads to the sequential or diauxic utilization of mixed sugars and reduces the co-utilization of glucose and xylose from lignocellulosic biomasses.
Lingya Wang +3 more
doaj +2 more sources
Release of glucose repression on xylose utilization in Kluyveromyces marxianus to enhance glucose-xylose co-utilization and xylitol production from corncob hydrolysate [PDF]
Microbial Cell Factories, 2019 Background Lignocellulosic biomass is one of the most abundant materials for biochemicals production. However, efficient co-utilization of glucose and xylose from the lignocellulosic biomass is a challenge due to the glucose repression in microorganisms.
Yan Hua +7 more
doaj +2 more sources
Modelling of glucose repression signalling in yeast Saccharomyces cerevisiae. [PDF]
FEMS Yeast Res, 2022 ABSTRACT Saccharomyces cerevisiae has a sophisticated signalling system that plays a crucial role in cellular adaptation to changing environments. The SNF1 pathway regulates energy homeostasis upon glucose derepression; hence, it plays an important role in various processes, such as metabolism, cell cycle and autophagy.
Persson S +3 more
europepmc +3 more sources
Structural insight into glucose repression of the mannitol operon. [PDF]
Sci Rep, 2019 AbstractCarbon catabolite repression is a regulatory mechanism to ensure sequential utilization of carbohydrates and is usually accomplished by repression of genes for the transport and metabolism of less preferred carbon compounds by a more preferred one.
Choe M +5 more
europepmc +4 more sources
Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality. [PDF]
PLoS Genetics, 2020 Metabolic adaptation is linked to the ability of the opportunistic pathogen Candida albicans to colonize and cause infection in diverse host tissues. One way that C.
Katherine Lagree +7 more
doaj +2 more sources
Alleviating glucose repression and enhancing respiratory capacity to increase itaconic acid production [PDF]
Synthetic and Systems Biotechnology, 2023 The Crabtree effect products ethanol and acetic acid can be used for itaconic acid (IA) production in Saccharomyces cerevisiae. However, both the IA synthesis and oxidative phosphorylation pathways were hampered by glucose repression when glucose was ...
Yaying Xu, Zhimin Li
doaj +2 more sources
Trehalose-6-phosphate promotes fermentation and glucose repression in Saccharomyces cerevisiae [PDF]
Microbial Cell, 2018 The yeast trehalose-6-phosphate synthase (Tps1) catalyzes the formation of trehalose-6-phosphate (T6P) in trehalose synthesis. Besides, Tps1 plays a key role in carbon and energy homeostasis in this microbial cell, as shown by the well documented loss of
Rebeca L. Vicente +5 more
doaj +2 more sources
Highly efficient conversion of xylose to ethanol without glucose repression by newly isolated thermotolerant Spathaspora passalidarum CMUWF1–2 [PDF]
BMC Microbiology, 2018 Background Efficient bioconversion of lignocellulosic biomass to bioethanol is one of key challenges in the situation of increasing bioethanol demand.
Nadchanok Rodrussamee +2 more
doaj +2 more sources
The Ability of a Charophyte Alga Hexokinase to Restore Glucose Signaling and Glucose Repression of Gene Expression in a Glucose-Insensitive Arabidopsis Hexokinase Mutant Depends on Its Catalytic Activity [PDF]
Frontiers in Plant Science, 2018 Hexokinases is a family of proteins that is found in all eukaryotes. Hexokinases play key roles in the primary carbon metabolism, where they catalyze the phosphorylation of glucose and fructose, but they have also been shown to be involved in glucose ...
Mikael Ulfstedt +3 more
doaj +2 more sources