Results 21 to 30 of about 84,281 (289)

Mechanisms of Metabolic Adaptation in Wine Yeasts: Role of Gln3 Transcription Factor

Fermentation, 2021
Wine strains of Saccharomyces cerevisiae have to adapt their metabolism to the changing conditions during their biotechnological use, from the aerobic growth in sucrose-rich molasses for biomass propagation to the anaerobic fermentation of ...
Aroa Ferrer-Pinós, Víctor Garrigós, Emilia Matallana, Agustín Aranda   +3 more
doaj   +1 more source

Kinetics of glucose repression of yeast cytochrome c [PDF]

Journal of Bacteriology, 1978
The kinetics of glucose repression of cytochrome c synthesis was measured by a radioimmune assay. When 5 or 10% glucose was added to a derepressed culture, the rate of cytochrome c synthesis was reduced to the repressed level with a half-life of 2 min.
R S, Zitomer, D L, Nichols
openaire   +2 more sources

Tup1 is critical for transcriptional repression in Quiescence in S. cerevisiae.

PLoS Genetics, 2022
Upon glucose starvation, S. cerevisiae shows a dramatic alteration in transcription, resulting in wide-scale repression of most genes and activation of some others. This coincides with an arrest of cellular proliferation.
Thomas B Bailey, Phaedra A Whitty, Eric U Selker, Jeffrey N McKnight, Laura E McKnight   +4 more
doaj   +1 more source

Transcriptomic Changes Induced by Deletion of Transcriptional Regulator GCR2 on Pentose Sugar Metabolism in Saccharomyces cerevisiae

Frontiers in Bioengineering and Biotechnology, 2021
Being a microbial host for lignocellulosic biofuel production, Saccharomyces cerevisiae needs to be engineered to express a heterologous xylose pathway; however, it has been challenging to optimize the engineered strain for efficient and rapid ...
Minhye Shin, Heeyoung Park, Sooah Kim, Eun Joong Oh, Deokyeol Jeong, Clarissa Florencia, Kyoung Heon Kim, Yong-Su Jin, Soo Rin Kim   +8 more
doaj   +1 more source

Peculiarities of hexose transport and catabolite repression regulation by hexose sensors HpGcr1 and HpHxs1 in the yeast Hansenula polymorpha

Біологічні студії, 2012
In the yeasts, as in the majority of microorganisms, glucose is the main source of carbon and energy, as well as a key effector molecule involved in transcriptional regulation.
O. G. Stasyk, I. O. Denega, N. I. Klymyshyn, N. O. Sybirna, O. V. Stasyk   +4 more
doaj   +1 more source

Deletion of the col-26 Transcription Factor Gene and a Point Mutation in the exo-1 F-Box Protein Gene Confer Sorbose Resistance in Neurospora crassa

Journal of Fungi, 2022
L-Sorbose induces hyperbranching of hyphae, which results in colonial growth in Neurospora crassa. The sor-4 gene, which encodes a glucose sensor that acts in carbon catabolite repression (CCR), has been identified as a sorbose resistance gene.
Kenshi Hirai, Takuya Idemoto, Shiho Kato, Akihiko Ichiishi, Fumiyasu Fukumori, Makoto Fujimura   +5 more
doaj   +1 more source

Carbon Catabolite Repression in Yeast is Not Limited to Glucose [PDF]

Scientific Reports, 2019
AbstractCells adapt their gene expression and their metabolism in response to a changing environment. Glucose represses expression of genes involved in the catabolism of other carbon sources in a process known as (carbon) catabolite repression. However, the relationships between “poor” carbon sources is less characterized. Here we show that in addition
Simpson-Lavy, Kobi, Kupiec, Martin
openaire   +2 more sources

Functional analysis of the global repressor Tup1 for maltose metabolism in Saccharomyces cerevisiae: different roles of the functional domains

Microbial Cell Factories, 2017
Background Tup1 is a general transcriptional repressor of diverse gene families coordinately controlled by glucose repression, mating type, and other mechanisms in Saccharomyces cerevisiae. Several functional domains of Tup1 have been identified, each of
Xue Lin, Ai-Qun Yu, Cui-Ying Zhang, Li Pi, Xiao-Wen Bai, Dong-Guang Xiao   +5 more
doaj   +1 more source

Profiling proteomic responses to hexokinase-II depletion in terpene-producing Saccharomyces cerevisiae

Engineering Microbiology, 2023
Hexokinase II (Hxk2) is a master protein in glucose-mediated transcriptional repression signaling pathway. Degrading Hxk2 through an auxin-inducible protein degradation previously doubled sesquiterpene (nerolidol) production at gram-per-liter levels in ...
Zeyu Lu, Qianyi Shen, Lian Liu, Gert Talbo, Robert Speight, Matt Trau, Geoff Dumsday, Christopher B. Howard, Claudia E. Vickers, Bingyin Peng   +9 more
doaj   +1 more source

The transcription factor Snf1p is involved in a Tup1p-independent manner in the glucose regulation of the major methanol metabolism genes of Hansenula polymorpha

Genetics and Molecular Biology, 2003
Hansenula polymorpha is a methylotrophic yeast widely employed in biotechnology as a ''protein factory''. Most promoters used for heterologous protein expression, like MOX (methanol oxidase) and DAS (di-hydroxy acetone synthase), are involved in the ...
Marcos A. Oliveira, Victor Genu, Anita P.T. Salmazo, Dirce M. Carraro, Gonçalo A.G. Pereira   +4 more
doaj   +1 more source