Results 81 to 90 of about 181,335 (186)

Glucose-lowering effect of DLBS3233 is mediated through phosphorylation of tyrosine and upregulation of PPARγ and GLUT4 expression

open access: yesInternational Journal of General Medicine, 2011
Olivia Mayasari Tandrasasmita1, Deasy Diah Wulan1, Florensia Nailufar1, James Sinambela2, Raymond Rubianto Tjandrawinata1,21Division of Molecular Pharmacology, 2Division of Phytochemistry, Dexa Laboratories of Biomolecular Sciences, Dexa Medica Group ...
Tandrasasmita OM   +4 more
doaj  

Enhancement of Glucose Uptake by Meso-Dihydroguaiaretic Acid through GLUT4 Up-Regulation in 3T3-L1 Adipocytes

open access: yesMolecules, 2017
Type 2 diabetes is characterized by insulin resistance, which leads to increased blood glucose levels. Adipocytes are involved in the development of insulin resistance, resulting from the dysfunction of the insulin signaling pathway.
Anna Lee   +10 more
doaj   +1 more source

Surfactin alleviates insulin resistance by modulating the AMPK/PI3K/Akt signalling pathway and inactivating inflammatory pathways

open access: yesJournal of Future Foods
Type 2 diabetes mellitus (T2DM) is accompanied by insulin resistance in liver and peripheral tissue. Bacillus amyloliquefaciens fmb50 produces lipopeptide surfactin, which has a wide range of biological activities.
Xiaoyu Chen   +6 more
doaj   +1 more source

miR-146b Inhibits Glucose Consumption by Targeting IRS1 Gene in Porcine Primary Adipocytes

open access: yes, 2018
Adipose tissue plays an important role in energy metabolism. Adipose dysfunction is closely related to obesity and type II diabetes. Glucose uptake is the key step for fat synthesis in adipocyte.
Jia-Jie Sun   +7 more
core   +1 more source

Acute bout of exercise induced prolonged muscle glucose transporter-4 translocation and delayed counter-regulatory hormone response in type 1 diabetes

open access: yesPLOS ONE, 2017
Previous studies have demonstrated that an acute bout of aerobic exercise induces a subsequent delayed onset of hypoglycemia among patients with type 1 diabetes. However, the mechanisms of exercise-induced hypoglycemia in type 1 diabetes are still unclear.
Koji Sato   +3 more
openaire   +4 more sources

Interleukin-18 (rs187238) and glucose transporter 4 (rs5435) polymorphisms in Euro-Brazilians with type 1 diabetes.

open access: yesGenetics and molecular research : GMR, 2018
Type 1 diabetes (T1D) is an autoimmune disease with a strong genetic component that has been associated with several genetic loci. Interleukin 18 (IL-18) is a potent proinflammatory cytokine, which is involved in the innate and adaptive immune responses, and in the pathogenesis of various diseases including T1D.
Y, Al-Lahham   +6 more
openaire   +1 more source

The Role of GABA and Insulin Regulated Aminopeptidase on Insulin Resistance and GLUT4 in Prediabetes and Type 2 Diabetes Mellitus

open access: yesمجله كليه طب الكندي
Background: Different proposed mechanisms for insulin resistance have been put forth to understand the relationship and changes in insulin resistance. Looking at the levels of insulin, the neurotransmitter gamma-aminobutyric acid, glucose transport type
Ismael Sadeq Khashan   +1 more
doaj   +1 more source

Acute hypoxic preconditioning prevents palmitic acid-induced cardiomyocyte apoptosis via switching metabolic GLUT4-glucose pathway back to CD36-fatty acid dependent

open access: yes, 2018
[[abstract]]Metabolic syndrome is a risk factor for the development of cardiovascular diseases. Myocardial cell damage leads to an imbalance of energy metabolism, and many studies have indicated that short-term hypoxia during myocardial cell injury has a
Che, Yeh-Peng;Chen, Yeh-Peng;Kuo, Wei-Wen;Rathinasamy;Baskaran, Rathinasamy;Cecilia-Hsua;Day, Cecilia-Hsuan;Che, Ray-Jade;Chen, Ray-Jade;Wen, Su-Ying;Tsung-Jung, H;Ho, Tsung-Jung;Viswanadha;Padma, Viswanadha Vijaya;Kuo, Chia-Hua;黃志揚;Huang, Chih-yang   +1 more
core   +1 more source

Exercise affects cardiac metabolism.

open access: yes, 2013
A: A strong trend towards up-regulation of genes participating in the metabolism of lipids was seen only for the high-intensity regime compared with control, while the metabolism of carbohydrates (B) was not necessarily affected.
Vicente Castro (277192)   +7 more
core   +1 more source

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