Results 61 to 70 of about 181,335 (186)

The clinical effectiveness of sodium-glucose co-transporter-2 inhibitors on prognosis of patients with chronic obstructive pulmonary disease and diabetes

open access: yesNature Communications
Diabetes is common in patients with chronic obstructive pulmonary disease. Sodium-glucose co-transporter-2 inhibitors are effective in treating type 2 diabetes and provide benefits for conditions like cardiovascular and kidney diseases.
Jheng-Yan Wu   +11 more
doaj   +1 more source

Insulin receptor and insulin-responsive glucose transporter (GLUT 4) mutations and polymorphisms in a welsh type 2 (non-insulin-dependent) diabetic population [PDF]

open access: yesDiabetologia, 1992
We have recently examined the exons encoding the insulin receptor tyrosine kinase domain and GLUT 4 in 30 subjects with Type 2 (non-insulin-dependent) diabetes mellitus using a molecular scanning approach. The variant sequences Val-Met985 and Lys-Glu1068 of the insulin receptor and Val-Ile383 of GLUT 4 were each separately found in three different ...
S, O'Rahilly   +5 more
openaire   +2 more sources

Cellular and molecular cues of glucose sensing in the rat olfactory bulb

open access: yesFrontiers in Neuroscience, 2014
In the brain, glucose homeostasis of extracellular fluid is crucial to the point that systems specifically dedicated to glucose sensing are found in areas involved in energy regulation and feeding behavior.
Dolly eAl Koborssy   +6 more
doaj   +1 more source

Physical exercise induces increased translocation of type 4 glucose transporters (GLUT4): a systematic review

open access: yesRetos
The purpose of this study is to highlight the impact of exercise on increasing GLUT4 translocation in cell membranes. This study searches many journal databases, including Embase, Pubmed, Web of Science, and Scopus, as part of a systematic review methodology.
Novadri Ayubi   +4 more
openaire   +2 more sources

Myocardial infarction in rats causes partial impairment in insulin response associated with reduced fatty acid oxidation and mitochondrial gene expression

open access: yes, 2010
ObjectiveMyocardial infarction leads to contractile dysfunction. In patients with diabetes, impaired contractility has been associated with the loss of insulin effects and mitochondrial dysfunction.
Amorim, Paulo A.   +13 more
core   +1 more source

Cardiac contraction-induced GLUT4 translocation requires dual signaling input [PDF]

open access: yes, 2015
Contraction-induced translocation of glucose transporter type-4 (GLUT4) to the sarcolemma is essential to stimulate cardiac glucose uptake during increased energy demand.
Glatz, Jan F. C.   +3 more
core   +1 more source

Effect of Dietary Silk Peptide on Obesity, Hyperglycemia, and Skeletal Muscle Regeneration in High-Fat Diet-Fed Mice

open access: yes, 2020
Obesity is associated with excess body fat accumulation that can cause hyperglycemia and reduce skeletal muscle function and strength, which characterize the development of sarcopenic obesity.
Jeong-Yong Lee   +5 more
core   +1 more source

Medicinal Plants with Multiple Effects on Diabetes Mellitus and Its Complications: a Systematic Review [PDF]

open access: yes, 2018
Purpose of Review This systematic review describes evidence concerning medicinal plants that, in addition to exerting hypoglycemic effects, decrease accompanying complications such as nephropathy, neuropathy, retinopathy, hypertension, and/or ...
Rafieian-Kopaei, Mahmoud.   +8 more
core   +1 more source

The effect of gelatinized brown rice extract on type 2 diabetes mellitus via inhibition of insulin resistance mediators in HepG2 cells

open access: yesDiscover Food
The purpose of this study evaluated effects of gelatinized brown rice extract (GBE) on type 2 diabetes mellitus by analyzing antioxidant activity, polysaccharide-degrading enzymes activity, and regulation of insulin secretion and glucose transport ...
Min Ho Kang   +4 more
doaj   +1 more source

Gelidium elegans Extract Ameliorates Type 2 Diabetes via Regulation of MAPK and PI3K/Akt Signaling

open access: yes, 2018
Gelidium elegans, a red alga native to the Asia Pacific region, contains biologically active polyphenols. We conducted a molecular biological study of the anti-diabetic effect of Gelidium elegans extract (GEE) in C57BL/KsJ-db/db mice.
Jia Choi   +3 more
core   +1 more source

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