Results 71 to 80 of about 181,335 (186)

Stress-induced hyperglycemia and expression of glucose cell transport genes in skeletal muscle of critically ill patients: a cross-sectional study [PDF]

Archives of Endocrinology and Metabolism
Objective: To explore the association between diabetes and stress-induced hyperglycemia with skeletal muscle expression of key genes related to glucose transport. Methods: This is a cross-sectional study.
Priscila Bellaver, Daisy Crispim, Lílian Rodrigues Henrique, Cristiane Bauermann Leitão, Ariell Freires Schaeffer, Tatiana Helena Rech, Diego Paluszkiewicz Dullius   +6 more
doaj   +1 more source

Biochemical and Molecular Mechanisms of Glucose Uptake Stimulated by Physical Exercise in Insulin Resistance State: Role of Inflammation [PDF]

Arquivos Brasileiros de Cardiologia
Obesity associated with systemic inflammation induces insulin resistance (IR), with consequent chronic hyperglycemia. A series of reactions are involved in this process, including increased release of proinflammatory cytokines, and activation of c-Jun N ...
Filipe Ferrari, Patrícia Martins Bock, Marcelo Trotte Motta, Lucas Helal   +3 more
doaj   +4 more sources

Effects of daipose-specific glucose transporter type 4 expression on glucose homeostasis mediated through alterations in adipose tissue composition

, 2012
Thesis (M.A.)--Boston University PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request.
Dwyer, Peter M.
core  

Promotion of glucose uptake by mulberry leaf extract and its active component 1-deoxynojirimycin in C2C12 cells

Applied Biological Chemistry
Mulberry leaf extract (MLE) is a proprietary extract derived from the leaves of Morus alba, contains high concentrations of 1-deoxynojirimycin (DNJ), which inhibits intestinal glucose uptake and improves glucose tolerance.
Ngoc Han Le Thi, Jun Hyung Park, Min Ji Han, Seon Hwa Kim, Tae Hoon Kim, Dong-Wook Kim, Seung Hyun Kim, Ki Sung Kang   +7 more
doaj   +1 more source

A Lanosteryl triterpene from Protorhus longifolia augments insulin signaling in type 1 diabetic rats

BMC Complementary and Alternative Medicine, 2018
Background A substantial literature supports antidiabetic properties of the lanosteryl triterpene (methyl-3β-hydroxylanosta-9,24-dien-21-oate, RA-3) isolated from Protorhus longifolia stem bark.
Sihle Ephraim Mabhida, Rabia Johnson, Musawenkosi Ndlovu, Nonhlakanipho Felicia Sangweni, Johan Louw, Andrew Opoku, Rebamang Anthony Mosa   +6 more
doaj   +1 more source

Diagram of the conditions observed in 3-AT-treated adipocytes.

, 2016
The increased hydrogen peroxide production leads to lower PPARγ expression and NF-κB activation, while decreasing the expression of important enzymes in metabolism, all of which finally reduce glucose uptake and lipolysis.
Francisco Javier Ruiz-Ojeda (3214866), Carolina Gomez-Llorente (311822), Concepción María Aguilera (754931), Azahara Iris Rupérez (3214863), Angel Gil (311830)   +4 more
core   +1 more source

Disrupted glucose homeostasis and skeletal muscle-specific glucose uptake in an exocyst knockout mouse model

, 2021
Skeletal muscle is responsible for the majority of glucose disposal following meals, and this is achieved by insulin-mediated trafficking of glucose transporter type 4 (GLUT4) to the cell membrane.
Nakamura, Nicole, Carter, Lamar, Polgar, Noemi, Kim, Jason K, Ha, Herena, Pitts, Matthew W., Young, Madison, Torres, Daniel, Suk, Sujin, Noh, Hye Lim, Fujimoto, Brent A.   +10 more
core   +2 more sources

Effects of SGLT-2 inhibitors on clinical and biological hyperandrogenism and menstruation irregularities in patients with polycystic ovary syndrome: A systematic review of randomized trials

SAGE Open Medicine
Introduction: Polycystic ovary syndrome is a common chronic condition characterized by insulin resistance and hyperandrogenism, leading to significant health risks and impaired quality of life.
Houcem Elomma Mrabet, Houda Ben Salem, Taieb Ach, Asma Ben Abdelkarim, Wafa Alaya   +4 more
doaj   +1 more source

Grp1 Plays a Key Role in Linking Insulin Signaling to Glut4 Recycling

, 2012
SummaryThe glucose transporter type 4 (glut4) is critical for metabolic homeostasis. Insulin regulates glut4 by modulating its expression on the cell surface. This regulation is mainly achieved by targeting the endocytic recycling of glut4.
Malaby, Andrew W., Hsu, Victor W., Famulok, Michael, Sabe, Hisataka, Lambright, David G., Li, Jian   +5 more
core   +1 more source

Sitagliptin downregulates retinol-binding protein 4 and upregulates glucose transporter type 4 expression in a type 2 diabetes mellitus rat model.

International journal of clinical and experimental medicine, 2016
The present study was designed to investigate the effects of sitagliptin on metabolic parameters as well as the expression levels of retinol-binding protein 4 (RBP4) and glucose transporter type 4 (GLUT4) in a rat model of type 2 diabetes mellitus.
Honglin, Hu, Min, Xu, Renjuan, Qi, Youmin, Wang, Changjiang, Wang, Jiongjiong, Liu, Li, Luo, Li, Xia, Zhaohui, Fang   +8 more
openaire   +1 more source