Anti-biofilm and anti-glucosyltransferase effects of nano liposomal plant extracts against Streptococcus mutans [PDF]
Scientific ReportsThe role of Streptococcus mutans in the initiation of caries is related to its acidogenicity, aciduricity, and polysaccharides extracellular layer production by glucosyltransferases in dental biofilms.
Faraz Radmand +7 more
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Exopolysaccharides of Streptococcus mutans Enhance Oral Colonisation and Drug Tolerance in Helicobacter pylori [PDF]
International Dental JournalIntroduction and aims: The oral cavity is an extragastric reservoir for Helicobacter pylori (H. pylori), preventing its gastric eradication and causing recurrence. However, the oral environment is not ideal for H.
Yujia Hao +4 more
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Water-insoluble exopolysaccharide synthesized by glucosyltransferases mediates the antibacterial activity of ClyR against Streptococcus mutans [PDF]
Journal of Oral MicrobiologyBackground Dental caries is a widespread global health issue strongly associated with Streptococcus mutans. Bacteriophage-derived lytic enzymes such as ClyR hold considerable promise as antibacterial potential, but the molecular mechanisms underlying ...
Qizhao Ma +8 more
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A novel selective medium Sucrose-Bacitracin agar 10 for accurate isolation and identification of Streptococcus mutans [PDF]
BMC Oral HealthBackground To develop and evaluate Sucrose-Bacitracin agar with 10% sucrose (SB-10), a novel selective medium designed to enhance the isolation and identification of Streptococcus mutans, a key cariogenic pathogen in dental caries.
Yuwen Fang +6 more
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Molecular insights into antibiofilm inhibitors of Streptococcus mutans glucosyltransferases through in silico approaches [PDF]
Scientific ReportsStreptococcus mutans, a primary cariogenic bacterium, plays a central role in dental caries, one of the most widespread chronic diseases globally. Glucosyltransferases (GTFs) are key virulence factors in this process, as they synthesize extracellular ...
Lubna Atta +6 more
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Structural basis of collagen glucosyltransferase function and its serendipitous role in kojibiose synthesis [PDF]
Nature CommunicationsCollagen glucosyltransferases catalyze collagen glucosylation critical for biology and diseases, yet their structural regulation remains unclear. Here, we report crystal structures of a mimiviral collagen glucosyltransferase in its apo form and in ...
Jeong Seon Kim +12 more
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The biosynthesis of trillin 6′-O-glucoside: A low-abundance yet pharmacologically active polyphyllin from Paris polyphylla [PDF]
Synthetic and Systems BiotechnologyNatural products from medicinal plants serve as an invaluable resource for drug discovery and development. However, low-abundance natural products are often understudied due to the challenges of obtaining sufficient quantities for pharmacological testing
Yaran Suo +9 more
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Nasal immunization with Streptococcus mutans membrane vesicles and eggshell-derived hydroxyapatites elicits enhanced antigen-specific mucosal IgA responses [PDF]
Scientific ReportsNasal vaccines characterized by secretory IgA (SIgA) induction are effective in preventing mucosal infection. SIgA induction is potentiated by mucosal adjuvants, and the exploration of new safe and effective candidates is important.
Tomomi Hashizume-Takizawa +5 more
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The well-coordinated linkage between acidogenicity and aciduricity via insoluble glucans on the surface of Streptococcus mutans. [PDF]
, 2015 Streptococcus mutans is considered the principal cariogenic bacterium for dental caries. Despite the recognition of their importance for cariogenesis, the possible coordination among S.
Guo, Lihong +4 more
core +1 more source
Frontiers in Microbiology, 2019 Temporin-GHc (GHc) and temporin-GHd (GHd) produced by the frog Hylarana guentheri had shown broad-spectrum antibacterial activities against bacteria and fungi.
Hengren Zhong +6 more
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