腫瘍細胞におよぼす glucuronic acid, Na-glucuronate, glucuronic amide および pyridoxal phosphate の影響を MTK 肉腫-III, エールリッヒ腹水癌および HeLa 細胞を用いて in vivo と in vitro で観察した。腫瘍細胞はいずれの薬物処理においても顕著な異常は示さなかった。また, 処理動物の生存日数は対照群と大差なかった。高濃度処理の場合にのみ, 細胞の分裂頻度がわずかながら増大し, HeLa 細胞の細胞質内にグリコーゲンと推定される微少顆粒が一時的に出現するのが観察された。
Yanagi Kimura
openaire +4 more sources
THE FATE OF INJECTED SODIUM GLUCURONATE AND GLUCURONE IN THE RAT [PDF]
G.C. Butler, Marian A. Packham
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Semi-synthetic glycoconjugate vaccine lead against Acinetobacter baumannii 17978 [PDF]
Acinetobacter baumannii is a opportunistic bacterial pathogen responsible for serious nosocomial infections that is becoming increasingly resistant against antibiotics. Capsular polysaccharides (CPS) that cover A.
Hu, J.+4 more
core +4 more sources
Pectin-Based Formulations for Controlled Release of an Ellagic Acid Salt with High Solubility Profile in Physiological Media [PDF]
Among bioactive phytochemicals, ellagic acid (EA) is one of the most controversial because its high antioxidant and cancer-preventing effects are strongly inhibited by low gastrointestinal absorption and rapid excretion.
Antenucci S.+7 more
core +5 more sources
Regulating Retinoic Acid Availability during Development and Regeneration: The Role of the CYP26 Enzymes. [PDF]
This review focuses on the role of the Cytochrome p450 subfamily 26 (CYP26) retinoic acid (RA) degrading enzymes during development and regeneration. Cyp26 enzymes, along with retinoic acid synthesising enzymes, are absolutely required for RA homeostasis
Roberts, C
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Large quantities (>3 g) of a new series of alkyl uronates were synthesized in two steps from commercial methyl hexopyranosides. Firstly, several tens of grams of free methyl α-d-glucopyranoside were selectively and quantitatively oxidized into ...
Huiling Lu+5 more
doaj +1 more source
Identify of a tilapia pheromone released by dominant males that primes females for reproduction [PDF]
Knowledge of the chemical identity and role of urinary pheromones in fish is scarce, yet necessary to understand the integration of multiple senses in adaptive responses and the evolution of chemical communication.
Adelino V.M. Canario+28 more
core +1 more source
Olfactory sensitivity to steroid glucuronates in Mozambique tilapia suggests two distinct and specific receptors for pheromone detection [PDF]
Cichlids offer an exciting opportunity to understand vertebrate speciation; chemical communication could be one of the drivers of African cichlid radiation.
Canario, Adelino V. M.+2 more
core +1 more source
The Glycobiome of the Rumen Bacterium Butyrivibrio proteoclasticus B316T Highlights Adaptation to a Polysaccharide-Rich Environment [PDF]
Determining the role of rumen microbes and their enzymes in plant polysaccharide breakdown is fundamental to understanding digestion and maximising productivity in ruminant animals.
Altermann, Eric+11 more
core +4 more sources
Glucuronoyl Esterase Screening and Characterization Assays Utilizing Commercially Available Benzyl Glucuronic Acid Ester [PDF]
Research on glucuronoyl esterases (GEs) has been hampered by the lack of enzyme assays based on easily obtainable substrates. While benzyl d-glucuronic acid ester (BnGlcA) is a commercially available substrate that can be used for GE assays, several ...
Charavgi, M. D.+4 more
core +2 more sources