Results 101 to 110 of about 41,898 (332)
Conditions for solid-phase extraction of urinary bile acids with octadecylsilane-bonded silica
Journal of Lipid Research, 1994 Fast atom bombardment mass spectrometry was used as a detection method in a study of the extraction of urinary bile acids with octadecylsilane-bonded silica.
E Wahlén +4 more
doaj +1 more source
Drug Testing and Analysis, EarlyView.ABSTRACT Hair analysis is increasingly used in forensic toxicology; however, result interpretation may be influenced by cosmetic hair treatments. Although the effects of bleaching, dyeing, and thermal straightening have already been evaluated, data on permanent chemical hair straightening are scarce, particularly under in vivo conditions.
Miriam Blanco‐Ces +5 more
wiley +1 more source
Enzymatic Synthesis of ?-D-Glucuronides in an Enzyme Membrane Reactor
CHIMIA, 1999 The production of two O-glucuronides in an enzyme membrane reactor on a 100 to 200 mg scale was examined. The aglycons were conjugated with the co-substrate ?-D-uridine diphosphoglucuronic acid (UDPGA) in the presence of a guinea-pig liver ...
Ulrike Pfaar +4 more
doaj
Journal of Lipid Research, 1986 The ability of rat liver microsomes to catalyze UDP-glucuronic acid-dependent glucuronidation of monohydroxy-bile acids was examined. The following bile acids were used as substrates, each as the 3 alpha and 3 beta epimer: 3-hydroxy-5 beta-cholanoic acid
A Radomińska-Pyrek +5 more
doaj +1 more source
Synthesis of cortol 3-glucuronides and cortolone 3-glucuronides.
Chemical and Pharmaceutical Bulletin, 1984 The synthesis of the 3-glucuronides of 20α-cortolone and their 20β-epimers is described. The cortol 20, 21-diacetates (3, 10) and cortolone 20, 21-diacetates (6, 12) were the key intermediates. Sodium borohydride reduction of the carbonyl group at C-20 in 21-acetoxy-3α, 11β, 17α-trihydroxy-5β-pregnan-20-one 3-tert-butyldimethylsilyl ether (1) or its 11-
H, Hosoda, H, Yokohama, T, Nambara
openaire +3 more sources
The effects of Bilirubin and Bilirubin-di-taurate on ischemia reperfusion injruy in a rat model of kidney transplantation [PDF]
, 2011 Background: Heme oxygenase-1 (HO-1) is the rate-limiting enzyme in the conversion of heme into biliverdin, carbon monoxide (CO) and free iron. Biliverdin is then subsequently reduced to bilirubin by the enzyme bilverdin reductase.
Thomas, Michael
core
Phenolic profiling of Veronica spp. grown in mountain, urban and sand soil environments [PDF]
, 2014 Veronica (Plantaginaceae) genus is widely distributed in different habitats. Phytochemistry studies are increasing because most metabolites with pharmacological interest are obtained from plants. The phenolic compounds of V. montana, V.
Barreira, João C.M. +6 more
core +1 more source
Drug Testing and Analysis, EarlyView.A new extraction method was developed and validated for the extraction of THC and THC‐COOH from capillary blood samples collected as dried blood spots. The extracts were analysed using HPLC–MS/MS resulting in high extraction efficiencies for both THC and THC‐COOH.
Matthias Bantle +7 more
wiley +1 more source
Metabolite profiling and pharmacokinetic evaluation of hydrocortisone in a perfused 3D human liver bioreactor [PDF]
, 2015 Endotoxin lipopolysaccharide (LPS) is known to cause liver injury primarily involving inflammatory cells such as Kupffer cells, but few in vitro culture models are applicable for investigation of inflammatory effects on drug metabolism. We have developed
Dyer, Rachel Lee +9 more
core +1 more source
Buck Wheat: Nutritional, Bioactive Characteristics, Health Benefits, and Side Effects
Future Postharvest and Food, EarlyView.ABSTRACT Micronutrient deficits have resulted from an over‐reliance on a small number of cereal crops for food security. The agricultural sector faces severe sustainability issues due to the rapid growth of the world's population and sudden climatic changes.
Momina Farooq +2 more
wiley +1 more source