Results 101 to 110 of about 6,846 (179)

Integrative analysis of the transcriptome, proteomics and metabolomics reveals key genes involved in the regulation of breast muscle metabolites in capons. [PDF]

BMC Genomics
Castration is widely used in poultry and livestock to enhance fat metabolism and improve the flavor, tenderness and juiciness of meat. However, the genetic regulatory mechanism underlying castration consequences have not been clarified.
Ye F, Deng ZD, Liu KY, Yao XM, Zheng WX, Yin Q, Hai X, Gan JK, Zhang ZF, Ma Z, Li H.   +10 more
europepmc   +2 more sources

Multi Layered Omics Approaches Reveal Glia Specific Alterations in Alzheimer's Disease: A Systematic Review and Future Prospects

Glia, Volume 73, Issue 3, Page 539-573, March 2025.
Main Point Graphical overview of the literature summarized in this review, spanning glia cells and levels of omics analysis present on Alzheimer's disease. ABSTRACT Alzheimer's disease (AD) is the most common neurodegenerative dementia with multi‐layered complexity in its molecular etiology.
Özkan İş, Yuhao Min, Xue Wang, Stephanie R. Oatman, Ann Abraham Daniel, Nilüfer Ertekin‐Taner   +5 more
wiley   +1 more source

Targeting the crosstalk between glutamine metabolism and tumor immune microenvironment for lung cancer immunotherapy

Interdisciplinary Medicine, Volume 3, Issue 2, March 2025.
This review summarizes the crosstalk between glutamine metabolism and the tumor immune microenvironment of lung cancer. Abstract Lung cancer remains one of the deadliest cancers globally, which may be attributed in part to a limited understanding of its development.
Jingyang Li, Li Xiang, Shaohui Wang, Yingrui Zhang, Shiyi Zhao, Di Zhang, Xianli Meng, Yi Zhang, Jin‐Ming Lin   +8 more
wiley   +1 more source

Twist instability in strongly correlated carbon nanotubes

, 2008
We show that strong Luttinger correlations of the electron liquid in armchair carbon nanotubes lead to a significant enhancement of the onset temperature of the putative twist Peierls instability.
A. M. Tsvelik, A. V. Andreev, A. M. Tsvelik, Dror Orgad, H. Suzuura, R. Saito, T. Giamarchi, Wei Chen   +7 more
core   +1 more source

GLUL stabilizes N-Cadherin by antagonizing β-Catenin to inhibit the progresses of gastric cancer

Acta Pharmaceutica Sinica B
Glutamate-ammonia ligase (GLUL, also known as glutamine synthetase) is a crucial enzyme that catalyzes ammonium and glutamate into glutamine in the ATP-dependent condensation.
Qiwei Jiang, Yong Li, Songwang Cai, Xingyuan Shi, Yang Yang, Zihao Xing, Zhenjie He, Shengte Wang, Yubin Su, Meiwan Chen, Zhesheng Chen, Zhi Shi   +11 more
doaj  

Minireview on Glutamine Synthetase Deficiency, an Ultra-Rare Inborn Error of Amino Acid Biosynthesis

Biology, 2016
Glutamine synthetase (GS) is a cytosolic enzyme that produces glutamine, the most abundant free amino acid in the human body. Glutamine is a major substrate for various metabolic pathways, and is thus an important factor for the functioning of many ...
Marta Spodenkiewicz, Carmen Diez-Fernandez, Véronique Rüfenacht, Corinne Gemperle-Britschgi, Johannes Häberle   +4 more
doaj   +1 more source

Specific Nature of Hydrolysis of Insulin and Tobacco Mosaic Virus Protein by Thermolysin [PDF]

Oxidized bovine insulin and tobacco mosaic virus protein used to determine hydrolysis specificity of ...
Jukes, T. H., Matsubara, H., Sasaki, R., Singer, A.   +3 more
core   +1 more source

Quantification of hepatocellular carcinoma heterogeneity with multiparametric magnetic resonance imaging

Scientific Reports, 2017
Tumour heterogeneity poses a significant challenge for treatment stratification. The goals of this study were to quantify heterogeneity in hepatocellular carcinoma (HCC) using multiparametric magnetic resonance imaging (mpMRI), and to report preliminary ...
Stefanie J. Hectors, Mathilde Wagner, Octavia Bane, Cecilia Besa, Sara Lewis, Romain Remark, Nelson Chen, M. Isabel Fiel, Hongfa Zhu, Sacha Gnjatic, Miriam Merad, Yujin Hoshida, Bachir Taouli   +12 more
doaj   +1 more source

Symmetric signaling by an asymmetric 1 erythropoietin : 2 erythropoietin receptor complex [PDF]

, 2008
Thesis (M. Eng.)--Massachusetts Institute of Technology, Biological Engineering Division, 2008.Includes bibliographical references (p. 43-46).One erythropoietin molecule binds asymmetrically to two identical receptor monomers via erythropoietin site 1 ...
Zhang, Yingxin
core  

Combined hepatocellular-cholangiocarcinomas exhibit progenitor features and activation of Wnt and TGFβ signaling pathways [PDF]

, 2017
Intrahepatic malignant tumours include hepatocellular carcinomas (HCC), cholangiocarcinomas (CC) and combined hepatocholangiocarcinomas (cHCC-CC), a group of rare and poorly characterized tumours that exhibit both biliary and hepatocytic differentiation.
Audebourg, Anne, Cavard, Catherine, Clément, Bruno, Coulouarn, Cédric, Dumont, Florent, Gilgenkrantz, Hélène, Jacques, Sébastien, Just, Pierre-Alexandre, Perret, Christine, Rubbia-Brandt, Laura, Terris, Benoît   +10 more
core