Results 51 to 60 of about 6,846 (179)

Single‐cell and spatial analyses reveal the association between gene expression of glutamine synthetase with the immunosuppressive phenotype of APOE+CTSZ+TAM in cancers

open access: yesMolecular Oncology, 2023
An immunosuppressive state is regulated by various factors in the tumor microenvironment (TME), including, but not limited to, metabolic plasticity of immunosuppressive cells and cytokines secreted by these cells.
Jinfen Wei   +8 more
doaj   +1 more source

Novel, acidic, and cold-adapted glycoside hydrolase family 8 endo-β-1,4-glucanase from an Antarctic lichen-associated bacterium, Lichenicola cladoniae PAMC 26568

open access: yesFrontiers in Microbiology, 2022
Endo-β-1,4-glucanase is a crucial glycoside hydrolase (GH) involved in the decomposition of cellulosic materials. In this study, to discover a novel cold-adapted β-1,4-D-glucan-degrading enzyme, the gene coding for an extracellular endo-β-1,4-glucanase ...
Do Young Kim   +8 more
doaj   +1 more source

Single-nucleus transcriptional profiling uncovers the reprogrammed metabolism of astrocytes in Alzheimer’s disease

open access: yesFrontiers in Molecular Neuroscience, 2023
Astrocytes play an important role in the pathogenesis of Alzheimer’s disease (AD). It is widely involved in energy metabolism in the brain by providing nutritional and metabolic support to neurons; however, the alteration in the metabolism of astrocytes ...
Li-Yuan Fan   +13 more
doaj   +1 more source

Comparative Genome Analysis of Two Heterotrophic Nitrifying Pseudomonas putida Strains Isolated from Freshwater Shrimp Ponds in Soc Trang Province

open access: yesFermentation, 2022
Nitrogen compounds, especially ammonia, are widely produced in aquaculture systems during cultivation. Ammonia has been investigated as a model compound for use by heterotrophic nitrifying bacteria.
Thanh Trung Tran   +5 more
doaj   +1 more source

Age-Related Meat Flavor Precursors of Naturally Grazed Sunit Sheep: Metabolomics and Transcriptomics Approaches. [PDF]

open access: yesFoods
This study elucidated the regulatory mechanisms of age-related meat flavor precursors in naturally grazed Sunit sheep of different ages (6, 18, and 30 months) by analyzing their metabolite and mRNA profiles.
Huang Y   +8 more
europepmc   +2 more sources

Kemelut politik zaman kesultanan Melayu dalam Tuhfat al-Nafis [PDF]

open access: yes, 2016
Kemelut politik yang berlaku dalam sesebuah kerajaan adalah antara punca utama tercetusnya kejatuhan sesebuah kerajaan tersebut. Permasalahan ini wujud, apabila terdapat pihak yang tidak lagi mengikut undang-undang negeri dan tidak lagi memperjuangkan ...
Amir Rullah Mohd Noor,   +1 more
core   +1 more source

Prion diseases disrupt glutamate/glutamine metabolism in skeletal muscle. [PDF]

open access: yesPLoS Pathog
In prion diseases (PrDs), aggregates of misfolded prion protein (PrPSc) accumulate not only in the brain but also in extraneural organs. This raises the question whether prion-specific pathologies arise also extraneurally.
Caredio D   +13 more
europepmc   +2 more sources

Fungsi Sastra Lisan “Tanduk” Masyarakat Genaharjo Kabupaten Tuban Bagi Masyarakat Pendukungnya [PDF]

open access: yes, 2016
This study aims to investigate the function of “tanduk” oral literature for its society. In this case, the people in question are society Genaharjo of Tuban district. Through the use of the theory of functions Alan Dundes and William R.
Suantoko, S. (Suantoko)
core   +3 more sources

Cellular and molecular outcomes of glutamine supplementation in the brain of succinic semialdehyde dehydrogenase‐deficient mice

open access: yesJIMD Reports, 2020
Succinic semialdehyde dehydrogenase deficiency (SSADHD) manifests with low levels of glutamine in the brain, suggesting that central glutamine deficiency contributes to pathogenesis.
Madalyn N. Brown   +6 more
doaj   +1 more source

Global gene expression in endometrium of high and low fertility heifers during the mid-luteal phase of the estrous cycle [PDF]

open access: yes, 2014
peer-reviewedBackground In both beef and dairy cattle, the majority of early embryo loss occurs within the first 14 days following insemination.
Diskin, Michael G.   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy