Results 81 to 90 of about 3,985 (137)

The cardioprotective mechanisms of draconis sanguis: An integrated network pharmacology, bioinformatics, and experimental validation study

Journal of Traditional Chinese Medical Sciences
Objective: To investigate the potential targets and mechanisms of Draconis Sanguis (DS), a valuable traditional Chinese medicine derived from the resin of the palm tree Daemonorops draco Bl (D. Sanguis, Xue Jie), in the treatment of myocardial infarction
Keyan Wang, Rongxin Zhu, Junjun Li, Binhua Yuan, Xiang Li, Yunlin Li, Mingyue Huang, Fangfang Rui, Chun Li, Wei Wang   +9 more
doaj   +1 more source

Label-free proteomic analysis reveals the hepatoprotective mechanism of gypenosides in liver injury rats

Frontiers in Pharmacology
Chronic liver disease, a long-term condition resulting from various causes such as alcohol abuse, metabolic disorders, and viral hepatitis, is becoming a significant global health challenge.
Yu Chen, Lizhou Ma, Yibo Wang, Jiarui Zhang, Tianhe Pei, Miao Wang   +5 more
doaj   +1 more source

Sequence of E. coli tRNA^Glulby automated sequential degradation

Nucleic Acids Research, 1975
Mayo Uziel, A.J. Weinberger
openaire   +2 more sources

Natural product virtual-interact-phenotypic target characterization: A novel approach demonstrated with Salvia miltiorrhiza extract

Journal of Pharmaceutical Analysis
Natural products (NPs) have historically been a fundamental source for drug discovery. Yet the complex nature of NPs presents substantial challenges in pinpointing bioactive constituents, and corresponding targets.
Rui Xu, Hengyuan Yu, Yichen Wang, Boyu Li, Yong Chen, Xuesong Liu, Tengfei Xu   +6 more
doaj   +1 more source

Targeting glutamine synthetase with AS1411-modified exosome-liposome hybrid nanoparticles for inhibition of choroidal neovascularization

Journal of Nanobiotechnology
Choroidal neovascularization (CNV) is a leading cause of visual impairment in wet age-related macular degeneration (wAMD). Recent investigations have validated the potential of reducing glutamine synthetase (GS) to inhibit neovascularization formation ...
Miaomiao Zhang, Xinyue Lu, Lifu Luo, Jinqiu Dou, Jingbo Zhang, Ge Li, Li Zhao, Fengying Sun   +7 more
doaj   +1 more source

Streamlined rAAV HeLaS3 producer cell line generation via GS selection. [PDF]

Sci Rep
Antunes M, Moura F, Sebastian IR, Alves P, Gomes-Alves P, Escandell JM.   +5 more
europepmc   +1 more source

SIRT6-GLUL axis: rewiring nitrogen metabolism in intrahepatic cholangiocarcinoma. [PDF]

Gut
Zhou H, Li H, Wu N, Calvisi DF.
europepmc   +1 more source

Exploring key genes in NAFLD linked to glutamine metabolism: A comprehensive analysis combining multi-omics, machine learning and SHAP. [PDF]

Asia Pac J Clin Nutr
Chen C, Liu W, Lan Y, Li F, Li X.
europepmc   +1 more source

Mechanistic study of glutamine metabolic reprogramming driving non-small cell lung cancer progression via the FGF17-FGFR4 axis mediating epithelial-mesenchymal transition. [PDF]

Front Mol Biosci
Kong Q, Wang X, Ding W.
europepmc   +1 more source

Glutamine synthetase deficiency enhances CD8 T cell survival and stress resilience in the tumor microenvironment. [PDF]

J Immunol
Fisher-Gupta EL, Hathaway ES, Perera JM, Jennings EQ, Chi C, Sewell AE, Stone SH, Muka JE, Sinard RC, DeCorte JA, Chen H, Wilson JT, Meiler J, Rathmell JC.   +13 more
europepmc   +1 more source