Results 31 to 40 of about 7,778 (157)

The relationship between polymorphisms in the glutamate cysteine ligase gene and asthma susceptibility [PDF]

, 2007
SummaryThe present study was designed to investigate an association of common -588C/T and -23G/T polymorphisms within glutamate cysteine ligase modifier subunit gene with susceptibility to bronchial asthma. A total of 435 ethnically Russian subjects were
Polonikov, A.V., I.V. Khoroshaya, V.I. Panfilov, Ivanov, V.P., A.V. Polonikov, Khoroshaya, I.V., Kozhuhov, M.A., M.A. Solodilova, Panfilov, V.I., Solodilova, M.A., V.P. Ivanov, M.A. Kozhuhov   +11 more
core   +1 more source

Urinary felinine excretion in intact male cats is increased by dietary cystine [PDF]

, 2008
Felinine is a branched-chain sulfur amino acid present in the urine of certain Felidae, including domestic cats. The objective of the present study was to determine if additional cystine and/or dietary N would increase felinine and N-acetylfelinine ...
Rogers, Q.R., Morton, R.H., Weidgraaf, K., Rutherfurd-Markwick, K.J., Hendriks, W.H.   +4 more
core   +1 more source

GABA synthetic and metabolic pathways in NE cells. [PDF]

, 2014
GLUD: glutamate dehydrogenase; GLS: glutaminase; GLUL: glutamate-ammonia ligase; GAD1: glutamate decarboxylase; ODC1: ornithine decarboxylase; ABP1: diamine oxidase; ABAT: GABA transaminase; SSAL: succinic semialdehyde; ALDH5A1: succinic acid ...
David Piwnica-Worms (178244), Joseph E. Ippolito (523145)   +1 more
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The glutamine synthetase gene family in Populus

BMC Plant Biology, 2011
Background Glutamine synthetase (GS; EC: 6.3.1.2, L-glutamate: ammonia ligase ADP-forming) is a key enzyme in ammonium assimilation and metabolism of higher plants.
Cánovas Francisco M, Kirby Edward G, Avila Concepción, Canales Javier, García-Gutiérrez Angel, Castro-Rodríguez Vanessa   +5 more
doaj   +1 more source

From Temperature Fluctuations to Precise Control: Biochemical Techniques Integrated Digital‐Intelligent Technology for Vegetable Preservation

Future Postharvest and Food, EarlyView.
The physiological effects and molecular responses of postharvest vegetables to temperature fluctuations, and multi‐technology integration strategies for maintaining postharvest vegetable quality. ABSTRACT Vegetables are indispensable agricultural products in the human diet. With the continuous growth of vegetable production and consumption, postharvest
Shuaishuai Dai, Kuo Chen, Xing Xing, Liqun Ma, Hongliang Zhu   +4 more
wiley   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

Cell Proliferation, EarlyView.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao, Lin Qi, Guijun Zou, Xingpeng Yang, Yizhao Ma, Zhifu Li, Xiaohui Du, Pengyue Zhao   +7 more
wiley   +1 more source

Schizophrenia and Oxidative Stress: Glutamate Cysteine Ligase Modifier as a Susceptibility Gene [PDF]

, 2006
Oxidative stress could be involved in the pathophysiology of schizophrenia, a major psychiatric disorder. Glutathione (GSH), a redox regulator, is decreased in patients’ cerebrospinal fluid and prefrontal cortex.
Do, Kim Quang, Cuénod, Michel, Solida, Alessandra, Deppen, Patricia, Matthey, Marie-Louise, Parnas, Josef, Preisig, Martin, Bovet, Pierre, Barral, Sandra, Gheorghita, Fulvia, Quang Do, Kim, Ott, Jurg, Wang, August G., Timm, Sally, Saraga, Michael, Werge, Thomas, Wang, August G, Tosic, Mirjana   +17 more
core   +1 more source

Natural product virtual-interact-phenotypic target characterization: A novel approach demonstrated with Salvia miltiorrhiza extract

Journal of Pharmaceutical Analysis
Natural products (NPs) have historically been a fundamental source for drug discovery. Yet the complex nature of NPs presents substantial challenges in pinpointing bioactive constituents, and corresponding targets.
Rui Xu, Hengyuan Yu, Yichen Wang, Boyu Li, Yong Chen, Xuesong Liu, Tengfei Xu   +6 more
doaj   +1 more source

High‐throughput multispecies quantitative polymerase chain reaction assays to study the effects of acute thermal stress in three species of Acipenser sturgeon

Journal of Fish Biology, EarlyView.
Abstract Fishes experience thermal stress in their natural environment that can be caused by natural or anthropogenic factors and can directly affect their physiology. In this study, we developed a multispecies OpenArray™ qPCR (quantitative polymerase chain reaction) ‘chip’ to measure the effects of acute thermal stress on the mRNA response of ...
Hossein Haghighi, Kyle Madden, William S. Bugg, Faith M. Penny, Scott A. Pavey, Nicholas J. Bernier, Kenneth M. Jeffries   +6 more
wiley   +1 more source

Microglial glutathione and glutamate: regulation mechanisms [PDF]

, 2009
Microglia, the immune cells of the central nervous system (CNS), are important in the protection of the CNS, but may be implicated in the pathogenesis of neuroinflammatory disease.
Fry, V.A.H.
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