Results 41 to 50 of about 12,568 (118)

Regulation of Pseudomonas putida genes involved in the metabolism of acidic amino acids [PDF]

open access: yes, 2003
Pseudomonas putida KT2440 has the ability to utilize a wide range of amino acids as carbon and nitrogen sources. Rapid growth of this organism is supported by the acidic amino acids (Asp and Glu) and their amides (Asn and Gln) when supplied as sole ...
Röhm, Klaus-Heinrich, Prof. Dr.   +1 more
core   +1 more source

Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer [PDF]

open access: yes, 2018
During tumorigenesis, the high metabolic demand of cancer cells results in increased production of reactive oxygen species. To maintain oxidative homeostasis, tumor cells increase their antioxidant production through hyperactivation of the NRF2 pathway ...
Altman   +81 more
core   +1 more source

Improving the flux distributions simulated with genome-scale metabolic models of Saccharomyces cerevisiae [PDF]

open access: yes, 2016
Genome-scale metabolic models (GEMs) can be used to evaluate genotype-phenotype relationships and their application to microbial strain engineering is increasing in popularity.
Alper   +63 more
core   +2 more sources

Transcriptome changes and cAMP oscillations in an archaeal cell cycle [PDF]

open access: yes, 2007
Background The cell cycle of all organisms includes mass increase by a factor of two, replication of the genetic material, segregation of the genome to different parts of the cell, and cell division into two daughter cells.
Baumann, Anke   +2 more
core   +3 more sources

Co-Cultures of Oophila Amblystomatis Between Ambystoma Maculatum and Ambystoma Gracile Hosts Show Host-Symbiont Fidelity [PDF]

open access: yes, 2019
A unique symbiosis occurs between embryos of the spotted salamander (Ambystoma maculatum) and a green alga (Oophila amblystomatis). Unlike most vertebrate host-symbiont relationships, which are ectosymbiotic, A.
Burns, John   +5 more
core   +1 more source

Postnatal development of rat retina: a continuous observation and comparison between the organotypic retinal explant model and in vivo development

open access: yesNeural Regeneration Research
The organotypic retinal explant culture has been established for more than a decade and offers a range of unique advantages compared with in vivo experiments and cell cultures.
Baoqi Hu   +10 more
doaj   +1 more source

GLUL Confers Perivascular Cancer‐Associated Fibroblasts With Pro‐Angiogenic Capacity to Promote Glioma Progression

open access: yesAdvanced Science
Glioblastoma (GBM) is a malignant brain tumor characterized by profound angiogenic activity and immunosuppressive features. A burgeoning body of research has focused on elucidating the functional effects of stromal cells within the tumor microenvironment
Qing Zhang   +4 more
doaj   +1 more source

Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats [PDF]

open access: yes, 2008
The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression in the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats.
Bell, Richard L.   +8 more
core   +1 more source

Integrative analysis of the transcriptome, proteomics and metabolomics reveals key genes involved in the regulation of breast muscle metabolites in capons

open access: yesBMC Genomics
Castration is widely used in poultry and livestock to enhance fat metabolism and improve the flavor, tenderness and juiciness of meat. However, the genetic regulatory mechanism underlying castration consequences have not been clarified.
Fei Ye   +10 more
doaj   +1 more source

Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings [PDF]

open access: yes, 2016
Herein, we have reviewed the role of glutamate, the major excitatory neurotransmitter in the brain, in a number of neurochemical, -physiological, and -behavioral processes mediating the development of alcohol dependence.
Aal-Aaboda   +212 more
core   +1 more source

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