Results 61 to 70 of about 18,690 (171)

Unraveling the Role of Ensheathing Cells and Perineural Fibroblasts in Olfactory Neurogenesis

Glia, Volume 73, Issue 12, Page 2407-2426, December 2025.
Main Points DEOs are similar to satellite glial cells. DECs react to neuronal injury by promoting lipid metabolism, but do not proliferate. ECs reduce gap junctions upon neuronal injury. Perineural fibroblasts also contribute to the injury response. ABSTRACT During development and following injury‐induced neurogenesis, olfactory ensheathing cells (OECs)
Katja Senf, Sandor Nietzsche, Martin Westermann, Eva M. Neuhaus   +3 more
wiley   +1 more source

Transcriptome changes and cAMP oscillations in an archaeal cell cycle [PDF]

, 2007
Background The cell cycle of all organisms includes mass increase by a factor of two, replication of the genetic material, segregation of the genome to different parts of the cell, and cell division into two daughter cells.
Baumann, Anke, Lange, Christian, Soppa, Jörg (Prof. Dr.)   +2 more
core   +3 more sources

Radiation‐Induced Biological Effects: Molecular and Cellular Mechanism, and Applications to Radiation/Nuclear Emergency and Cancer Therapy

MedComm, Volume 6, Issue 12, December 2025.
Radiation‐induced biological effects are an extremely complex and extensive mechanism that involves multiple aspects of physiological activities in organisms. In the medical field, utilizing the damaging effects of radiation to treat tumors is a commonly employed therapeutic approach.
Zhihe Hu, Yan Chen, Shengyi Yang, Shihai Diao, Le Ma, Chunmeng Shi   +5 more
wiley   +1 more source

Prion diseases disrupt glutamate/glutamine metabolism in skeletal muscle

PLoS Pathogens
In prion diseases (PrDs), aggregates of misfolded prion protein (PrPSc) accumulate not only in the brain but also in extraneural organs. This raises the question whether prion-specific pathologies arise also extraneurally.
Davide Caredio, Maruša Koderman, K. Frontzek, S. Sorce, Mario Nuvolone, Juliane Bremer, Giovanni Mariutti, Petra Schwarz, Lidia Madrigal, Marija Mitrovic, Stefano Sellitto, Nathalie Streichenberger, C. Scheckel, Adriano Aguzzi   +13 more
semanticscholar   +1 more source

Metagenomic Insights Into the Ecology, Taxonomy and Metabolic Capabilities of ‘Candidatus Darwinibacteriales’ Ord. Nov. (Formerly MBA03), a Potential Key Player in Anaerobic Digestion

Microbial Biotechnology, Volume 18, Issue 12, December 2025.
Metagenomic analysis of anaerobic digesters revealed a dominant, uncultured bacterial taxon—MBA03—now proposed as ‘Candidatus Darwinibacteriales’ ord. nov. This newly defined order includes potential syntrophic acetate‐oxidising bacteria (SAOB), suggesting a key role in methane production.
Roser Puchol‐Royo, Javier Pascual, Asier Ortega‐Legarreta, Pascal Otto, Jeroen Tideman, Sjoerd‐Jan de Vries, Christian Abendroth, Kristie Tanner, Manuel Porcar, Adriel Latorre‐Perez   +9 more
wiley   +1 more source

Prion diseases disrupt the glutamate/glutamine metabolism in skeletal muscle

bioRxiv
In prion diseases, aggregates of misfolded prion protein (PrPSc) accumulate not only in the brain but also in extraneural organs. This raises the question whether prion-specific pathologies arise also extraneurally.
Davide Caredio, Maruša Koderman, K. Frontzek, S. Sorce, M. Nuvolone, J. Bremer, Petra Schwarz, Stefano Sellitto, Nathalie Streichenberger, C. Scheckel, Adriano Aguzzi   +10 more
semanticscholar   +1 more source

Modification of Oxidative Stress Induced by Exposure to Arsenate in Rat Chondrocytes Treated With Chitosan–Glutathione Nanoparticles

Journal of Applied Toxicology, Volume 45, Issue 11, Page 2391-2399, November 2025.
ABSTRACT Nanoparticles can modify the signaling pathways related to the toxic effects of xenobiotics and their toxicity by adding compounds that alter the oxidation–reduction state, such as glutathione (GSH). This work aimed to evaluate the antioxidant capacity of chitosan–glutathione nanoparticles (NPs Q‐GSH) to modify lipoperoxidation induced by ...
Laura Denise López Barrera, Viridiana García García, Joselo Ramon Martínez Rosas, Elizabeth Soria‐Castro, Roberto Diaz Torres, Patricia Ramírez Noguera   +5 more
wiley   +1 more source

Postnatal development of rat retina: a continuous observation and comparison between the organotypic retinal explant model and in vivo development

Neural Regeneration Research
The organotypic retinal explant culture has been established for more than a decade and offers a range of unique advantages compared with in vivo experiments and cell cultures.
Baoqi Hu, Rui Wang, Hanyue Zhang, Xiou Wang, Sijia Zhou, Bo Ma, Yan Luan, Xin Wang, Xinlin Chen, Zhichao Zhang, Qianyan Kang   +10 more
doaj   +1 more source

Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats [PDF]

, 2008
The current study examined the effects of operant ethanol (EtOH) self-administration on gene expression in the nucleus accumbens (ACB) and amygdala (AMYG) of inbred alcohol-preferring (iP) rats.
Bell, Richard L., Carr, Lucinda G., Edenberg, Howard J., Kimpel, Mark W., Liang, Tiebing, McBride, William J., McClintick, Jeanette N., Rodd, Zachary A., Strother, Wendy N.   +8 more
core   +1 more source

Removal of Toxic Metabolites—Chelation: Manganese Disorders

Journal of Inherited Metabolic Disease, Volume 48, Issue 6, November 2025.
ABSTRACT Manganese (Mn) overload is a characteristic of multiple disease entities, from acquired manganism upon environmental or occupational overexposure, to end‐stage liver disease and certain genetic disorders. The latter include hypermanganesaemia with dystonia 1 and 2 caused by pathogenic variants in the genes encoding the Mn transporters SLC30A10
Hendrik Vogt, George E. Kostakis, Rupert Purchase, John Spencer, Karin Tuschl   +4 more
wiley   +1 more source