Results 91 to 100 of about 585,844 (339)
Near‐Infrared Organic Photovoltaic Electrodes for Subretinal Neurostimulation
Advanced Functional Materials, EarlyView.Organic photovoltaic electrodes based on the D18:Y6 blend enable precise and light‐controlled activation of retinal ganglion cells in a degenerating retina. NIR Light‐driven activation of retinal ganglion cells, tunable stimulation parameters, and biocompatibility with human retinal organoids highlight their potential for next‐generation prosthetics ...
Andrea Corna +10 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang +9 more
wiley +1 more source
Ultrafast glutamate sensors resolve high-frequency release at Schaffer collateral synapses
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Excitatory synapses convert presynaptic action potentials into chemical signals that are sensed by postsynaptic glutamate receptors. To eavesdrop on synaptic transmission, genetically encoded fluorescent sensors for glutamate have been ...
N. Helassa +9 more
semanticscholar +1 more source
Glutamate-Induced Hyperglycemia.
Experimental Biology and Medicine, 1967 SummaryPlasma glucose rose linearly with increasing amounts of glutamate up to a maximal dose of 0.2 mmoles/100 g body weight. The glutamate effect could not be explained by stoichiometric conversion of glutamate to glucose. Glutamate produced hyper-glycemia after 14-hour fast, at which time glucagon had no effect on glucose concentration ...
R, Marcus, G, Reaven
openaire +2 more sources
Advanced Functional Materials, EarlyView.Thermoelectric temperature sensors are developed that directly measure heat changes during optical‐based neural stimulation with millisecond precision. The sensors reveal the temperature windows for safe reversible neural modulation: 1.4–4.5 °C enables reversible neural inhibition, while temperatures above 6.1 °C cause permanent thermal damage.
Junhee Lee +9 more
wiley +1 more source
Chronic Glutamate Toxicity in Neurodegenerative Diseases—What is the Evidence?
Frontiers in Neuroscience, 2015 Together with aspartate, glutamate is the major excitatory neurotransmitter in the brain. Glutamate binds and activates both ligand-gated ion channels (ionotropic glutamate receptors) and a class of G-protein coupled receptors (metabotropic glutamate ...
J. Lewerenz, P. Maher
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.We fabricated a biomimetic dendrimer‐modified thin‐film nanocomposite membrane with a coordination‐assisted ion‐selective interface. pH‐responsive polypeptide sites preferentially bind Mg2+ and promote Li+ permeation, as predicted by density functional theory calculations of metal‐ligand interactions.
Mehrasa Yassari +7 more
wiley +1 more source
Glutamate Concentration in the Superior Temporal Sulcus Relates to Neuroticism in Schizophrenia
Frontiers in Psychology, 2018 Clinical studies suggest aberrant neurotransmitter concentrations in the brains of patients with schizophrenia (SCZ). Numerous studies have indicated deviant glutamate concentrations in SCZ, although the findings are inconsistent.
Johanna Balz +8 more
doaj +1 more source
Frontiers in Psychiatry, 2018 Recent evidence suggests that Alzheimer's disease (AD) and depression share common mechanisms of pathogenesis. In particular, deregulation of glutamate-mediated excitatory signaling may play a role in brain dysfunction in both AD and depression.
C. Madeira +6 more
semanticscholar +1 more source