Results 101 to 110 of about 662,038 (354)
Antibodies to the glutamate dehydrogenase of Plasmodium falciparum [PDF]
, 1986 Polyclonal antisera raised against Plasmodium knowlesi reacted with NADP-specific glutamate dehydrogenase (GLDH) of P. knowlesi, GLDH of P. falciparum and GLDH of Proteus spp. The antisera did not react with NAD(P) GLDH from bovine liver.
Cooksley, S +4 more
core
Glutamate-induced mitochondrial dysfunction in PC12 cells was improved by PFF treatment. [PDF]
, 2016 PC12 cells were stimulated with glutamate (5 mM, 24 h) in the presence or absence of PFF (10 μM). (A) Cells were immunolabelled with a Tomm20 antibody, followed by the addition of Cy3-conjugated secondary antibody.
Jwa-Jin Kim (581950) +12 more
core +1 more source
Targeting glutamate metabolism in chronic lung diseases
Clinical and Translational DiscoveryAmino acids are necessary for all life forms, which play various roles. Disorder of amino acid metabolism is now considered an important driving mechanism in diverse pulmonary conditions, particularly chronic lung diseases like chronic obstructive ...
Zhihou Guo, Furong Yan
doaj +1 more source
Alterations of Astrocytes in the Context of Schizophrenic Dementia
Frontiers in Pharmacology, 2020 The levels of the astrocyte markers (GFAP, S100B) were increased unevenly in patients with schizophrenia. Reactive astrogliosis was found in approximately 70% of patients with schizophrenia.
Vadim V. Tarasov +12 more
doaj +1 more source
Role of glutamate and NMDA receptors in Alzheimer’s disease
Journal of Alzheimer's Disease, 2016 Excitatory glutamatergic neurotransmission via N-methyl-d-aspartate receptor (NMDAR) is critical for synaptic plasticity and survival of neurons. However, excessive NMDAR activity causes excitotoxicity and promotes cell death, underlying a potential ...
Rui Wang, P. Reddy
semanticscholar +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
The glutamate post-synaptic density in schizophrenia [PDF]
, 2012 Non-competitive antagonists of the glutamate N-methyl-D-aspartate receptor (NMDAR) induce a broad range of schizophrenia-like symptoms in humans.
Matas, Emmanuel
core
Release of ATP and glutamate in the nucleus tractus solitarii mediate pulmonary stretch receptor (Breuer-Hering) reflex pathway [PDF]
, 2008 The Breuer-Hering inflation reflex is initiated by activation of the slowly adapting pulmonary stretch receptor afferents (SARs), which monosynaptically activate second-order relay neurones in the dorsal medullary nucleus of the solitary tract (NTS ...
Enrique Llaudet +13 more
core +1 more source
Translational Psychiatry, 2018 Autism spectrum disorder (ASD) is a pervasive neurodevelopmental syndrome with a high human and economic burden. The pathophysiology of ASD is largely unclear, thus hampering development of pharmacological treatments for the core symptoms of the disorder.
J. Horder +8 more
semanticscholar +1 more source
Interaction of Glutamate and Norvaline with Glutamate Dehydrogenase
The FASEB Journal, 2006 Glutamate Dehydrogenases from higher eukaryotes show complex allosteric behaviour associated with the utilization of glutamate as the amino acid substrate. While the cofactors NAD(P)+ and NAD(P)H have been demonstrated to bind to the enzyme with cooperative properties, kinetic studies suggest that the manifestations of cooperativity relie upon ...
Carolyn Scheel, Ellis Bell
openaire +1 more source