Involvement of kainate glutamate receptors in the modulation of neuronal transmission in brain areas involved in migraine pathophysiology [PDF]
Migraine pathophysiology is thought to involve activation of the trigeminal fibres which innervate dural structures. The nociceptive inflow from the meninges is relayed to the trigeminocervical complex (TCC), before ascending to higher brain areas ...
Andreou, A.
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Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived fas ligand [PDF]
Activated microglia may be detrimental to neuronal survival in a number of neurodegenerative diseases. Thus, strategies that reduce microglial neurotoxicity may have therapeutic benefit.
Taylor, DL +3 more
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Neuroprotection by Mitochondrial NAD Against Glutamate-Induced Excitotoxicity
Excitotoxicity is a pathological process that occurs in many neurological diseases, such as stroke or epilepsy, and is characterized by the extracellular accumulation of high concentrations of glutamate or other excitatory amino acids (EAAs ...
Bruna S. Paiva +7 more
doaj +1 more source
Effects of standardized extract of Ferula gummosa root on glutamate-induced neurotoxicity
Glutamate is one of the major excitatory neurotransmitters in the central nervous system. Increasing glutamate leads to neurodegenerative disease. Nowadays, plant medicine plays a role in the treatment of some disorders. In this research, we investigated
Maliheh Moradzadeh +4 more
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Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity [PDF]
A reduction in microglial activation and subsequent neurotoxicity may prove critical for neuroprotection in neurodegenerative diseases. We examined the expression and functionality of group III metabotropic glutamate (mGlu) receptors on microglia.
Taylor, D.L., Pocock, J.M., Diemel, L.T.
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Estudo bioquímico e comportamental em camundongos submetidos à infusão intracerebroventricular dos peptídeos beta-amilóide AB1-40 E AB25-35 e o papel neuroprotetor da atorvastatina [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.The accumulation and aggregation of beta-amyloid peptide (Aâ) in brain of patients with Alzheimer's disease results
Piermartiri, Tetsade Camboim Bizerra
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L-Glutamato: un aminoácido clave para las funciones sensoriales y metabólicas
El ácido glutámico como tal o en su forma ionizada L-glutamato (GLU) es uno de los aminoácidos más abundantes en la naturaleza debido a que cumple funciones importantes a nivel celular y sistémico.
Sonia Luz Albarracín +4 more
doaj
Glutamate tone in preBötzinger complex rhythmogenesis: ambient extracellular glutamate as a candidate excitability bias. [PDF]
Vázquez-Mendoza E +5 more
europepmc +1 more source
Molecular Determinants of Ligand Selectivity in Diverse Ionotropic Glutamate Receptors. [PDF]
Wang Y +3 more
europepmc +1 more source
Marco A Grados,1 Elizabeth B Atkins,2 Gabriela I Kovacikova,3 Erin McVicar4 1Division of Child and Adolescent Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, 2Department of Psychology, Smith College, Northampton, MA, 3Department ...
Grados MA +3 more
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