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Glutamate, Glutamate Receptors, and Downstream Signaling Pathways [PDF]
International Journal of Biological Sciences, 2013 Glutamate is a nonessential amino acid, a major bioenergetic substrate for proliferating normal and neoplastic cells, and an excitatory neurotransmitter that is actively involved in biosynthetic, bioenergetic, metabolic, and oncogenic signaling pathways. Glutamate signaling activates a family of receptors consisting of metabotropic glutamate receptors (
Willard, Stacey S. +1 more
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Pivotal Enzyme in Glutamate Metabolism of Poly-g-Glutamate-Producing Microbes
Life, 2013 The extremely halophilic archaeon Natrialba aegyptiaca secretes the L-homo type of poly-g-glutamate (PGA) as an extremolyte. We examined the enzymes involved in glutamate metabolism and verified the presence of L-glutamate dehydrogenases, L-aspartate ...
Tohru Kamei +2 more
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In vivo co-ordinated interactions between inhibitory systems to control glutamate mediated hippocampal excitability. [PDF]
, 2013 We present an overview of the long-term adaptation of hippocampal neurotransmission to cholinergic and GABAergic deafferentation caused by excitotoxic lesion of the medial septum.
Rodríguez Allué, Manuel José +3 more
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Kinetic model of the glutamate neuron-astrocytic system. N-acetylaspartylglutamate and glutamate carboxypeptidase [PDF]
, 2023 Kinetic model of excitatory synapse functioning with glutamate and N-acetylaspartylglutamate (NAAG) as neurotransmitters in a three-component system regarding neuroglial astrocytic cells and the glutamate carboxypeptidase (GCPII) enzyme has been ...
Svetlana, Tsybenova +2 more
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Glutamate Taste: Discrimination between the Tastes of Glutamate Agonists and Monosodium Glutamate in Rats [PDF]
Chemical Senses, 2004 Taste aversion studies have demonstrated that rats conditioned to avoid monosodium glutamate (MSG) with amiloride added to reduce the intensity of the sodium component of MSG taste, generalize this aversion to aspartic acid and to L-AP4, but not to ionotropic glutamate receptor agonists.
Delay, Eugene R. +3 more
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Glutamate-Ketamine Response. [PDF]
, 2016 Beta1 (14Hz– 20Hz), beta2 (20Hz– 30Hz), gamma (30Hz– 40Hz) PDs within the left parahippocampal gyrus exposed to surface injections of water (Water), 10−7 M glutamate and 10−9 M ketamine (10−7 G + 10−9 K), or 10−5 M glutamate and 10−7 M ketamine (10−5 G +
Lucas W. E. Tessaro (3373610) +4 more
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The Journal of Nutrition, 2000 Epileptic syndromes have very diverse primary causes, which may be genetic, developmental or acquired. In rodent models, altering glutamate receptor or glutamate transporter expression by knockout or knockdown procedures can induce or suppress epileptic seizures.
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Production of
Bioscience, Biotechnology, and Biochemistry, 1999 We studied production of D-glutamate from L-glutamate using a bioreactor consisting of two columns of sequentially connected immobilized glutamate racemase (EC 5.1.1.3, from Bacillus subtilis IFO 3336) and L-glutamate oxidase (EC 1.4.3.11, from Streptomyces sp.
OIKAWA, Tadao +5 more
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Differential localization of glutamate receptor subunits at the drosophila neuromuscular junction [PDF]
, 2004 The subunit composition of postsynaptic neurotransmitter receptors is a key determinant of synaptic physiology. Two glutamate receptor subunits, Drosophila glutamate receptor IIA (DGluRIIA) and DGluRIIB, are expressed at the Drosophila neuromuscular ...
Portman, Scott L. +5 more
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Сеченовский вестник, 2020 N-methyl-D-aspartate (NMDA) receptors belong to the group of inotropic glutamate receptors, which are found in rat cardiomyocytes.Aim. To evaluate the influence of a non-competitive antagonist of NMDA-receptors — МК-801, separately or in combination with
N. S. Govorushkina +11 more
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