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Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels
Cell Reports, 2021 Summary: Vesicular glutamate transporters (VGLUTs) fill synaptic vesicles with glutamate. VGLUTs were originally identified as sodium-dependent transporters of inorganic phosphate (Pi), but the physiological relevance of this activity remains unclear ...
Cyril Cheret +4 more
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Glutamate Taste: Discrimination between the Tastes of Glutamate Agonists and Monosodium Glutamate in Rats [PDF]
Chemical Senses, 2004 Taste aversion studies have demonstrated that rats conditioned to avoid monosodium glutamate (MSG) with amiloride added to reduce the intensity of the sodium component of MSG taste, generalize this aversion to aspartic acid and to L-AP4, but not to ionotropic glutamate receptor agonists.
Delay, Eugene R. +3 more
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The Journal of Nutrition, 2000 Epileptic syndromes have very diverse primary causes, which may be genetic, developmental or acquired. In rodent models, altering glutamate receptor or glutamate transporter expression by knockout or knockdown procedures can induce or suppress epileptic seizures.
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Production of
Bioscience, Biotechnology, and Biochemistry, 1999 We studied production of D-glutamate from L-glutamate using a bioreactor consisting of two columns of sequentially connected immobilized glutamate racemase (EC 5.1.1.3, from Bacillus subtilis IFO 3336) and L-glutamate oxidase (EC 1.4.3.11, from Streptomyces sp.
OIKAWA, Tadao +5 more
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A Mini-Review of the Role of Glutamate Transporter in Drug Addiction
Frontiers in Neurology, 2019 Goals: The development of new treatment for drug abuse requires identification of targetable molecular mechanisms. The pathology of glutamate neurotransmission system in the brain reward circuit is related to the relapse of multiple drugs.
Wenjun Wang +3 more
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Abnormalities in Glutamate Metabolism and Excitotoxicity in the Retinal Diseases
Scientifica, 2013 In the physiological condition, glutamate acts as an excitatory neurotransmitter in the retina. However, excessive glutamate can be toxic to retinal neurons by overstimulation of the glutamate receptors.
Makoto Ishikawa
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The role of glutamate receptors in the regulation of the tumor microenvironment
Frontiers in Immunology, 2023 Glutamate, as one of the most important carbon sources in the TCA cycle, is central in metabolic processes that will subsequently influence tumor progression.
Stephane Koda +8 more
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Differential Effects of Dietary MSG on Hippocampal Dependent Memory Are Mediated by Diet
Frontiers in Neuroscience, 2019 IntroductionFree glutamate is a common dietary flavor enhancer and is also an important excitatory neurotransmitter in the body. A good number of food additives which contain glutamate are found in the Western Diet, and this diet has also been linked to ...
Kathleen F. Holton +2 more
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Risk-Conferring Glutamatergic Genes and Brain Glutamate Plus Glutamine in Schizophrenia
Frontiers in Psychiatry, 2017 BackgroundThe proton magnetic resonance spectroscopy (1H-MRS) signals from glutamate (or the combined glutamate and glutamine signal—Glx) have been found to be greater in various brain regions in people with schizophrenia.
Juan R. Bustillo +26 more
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