Results 21 to 30 of about 502,486 (298)

Glutamate-pantothenate pathway promotes antibiotic resistance of Edwardsiella tarda

open access: yesFrontiers in Microbiology, 2023
Although cellular metabolic states have been shown to modulate bacterial susceptibility to antibiotics, the interaction between glutamate (Glu) and chloramphenicol (CAP) resistance remains unclear because of the specificity of antibiotics and bacteria ...
Bei-bei Yan   +10 more
doaj   +1 more source

Energetics of Glutamate Binding to an Ionotropic Glutamate Receptor [PDF]

open access: yesThe Journal of Physical Chemistry B, 2017
Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are responsible for the majority of excitatory transmission at the synaptic cleft. Mechanically speaking, agonist binding to the ligand binding domain (LBD) activates the receptor by triggering a conformational change that is transmitted to the transmembrane region, opening the ...
Alvin Yu, Albert Y. Lau
openaire   +4 more sources

Glutamate and Epilepsy [PDF]

open access: yesThe Journal of Nutrition, 2000
Epileptic syndromes have very diverse primary causes, which may be genetic, developmental or acquired. In rodent models, altering glutamate receptor or glutamate transporter expression by knockout or knockdown procedures can induce or suppress epileptic seizures.
openaire   +2 more sources

Glutamate Taste: Discrimination between the Tastes of Glutamate Agonists and Monosodium Glutamate in Rats [PDF]

open access: yesChemical Senses, 2004
Taste aversion studies have demonstrated that rats conditioned to avoid monosodium glutamate (MSG) with amiloride added to reduce the intensity of the sodium component of MSG taste, generalize this aversion to aspartic acid and to L-AP4, but not to ionotropic glutamate receptor agonists.
Delay, Eugene R.   +3 more
openaire   +2 more sources

Abnormalities in Glutamate Metabolism and Excitotoxicity in the Retinal Diseases

open access: yesScientifica, 2013
In the physiological condition, glutamate acts as an excitatory neurotransmitter in the retina. However, excessive glutamate can be toxic to retinal neurons by overstimulation of the glutamate receptors.
Makoto Ishikawa
doaj   +1 more source

Production ofD-Glutamate fromL-Glutamate with Glutamate Racemase andL-Glutamate Oxidase [PDF]

open access: yesBioscience, Biotechnology, and Biochemistry, 1999
We studied production of D-glutamate from L-glutamate using a bioreactor consisting of two columns of sequentially connected immobilized glutamate racemase (EC 5.1.1.3, from Bacillus subtilis IFO 3336) and L-glutamate oxidase (EC 1.4.3.11, from Streptomyces sp.
OIKAWA, Tadao   +5 more
openaire   +2 more sources

Cre-Activation in ErbB4-Positive Neurons of Floxed Grin1/NMDA Receptor Mice Is Not Associated With Major Behavioral Impairment

open access: yesFrontiers in Psychiatry, 2021
Extensive evidence suggests a dysfunction of the glutamate NMDA receptor (NMDAR) in schizophrenia, a severe psychiatric disorder with putative early neurodevelopmental origins, but clinical onset mainly during late adolescence.
Anne S. Mallien   +8 more
doaj   +1 more source

Effects of glutamate receptor activation on NG2-glia in the rat optic nerve [PDF]

open access: yes, 2009
NG2-glia are a substantial population of cells in the central nervous system (CNS) that can be identified by their specific expression of the NG2 chondroitin sulphate (CSPG).
Hubbard, Paul S.   +8 more
core   +1 more source

Similarity and Diversity of Presynaptic Molecules at Neuromuscular Junctions and Central Synapses

open access: yesBiomolecules, 2022
Synaptic transmission is essential for controlling motor functions and maintaining brain functions such as walking, breathing, cognition, learning, and memory.
Kenji Takikawa, Hiroshi Nishimune
doaj   +1 more source

A thioacetamide-induced hepatic encephalopathy model in C57BL/6 mice: a behavioral and neurochemical study Modelo de encefalopatia hepática induzida por tioacetamida em camundongos C57BL/6: estudo comportamental e neuroquímico

open access: yesArquivos de Neuro-Psiquiatria, 2010
OBJECTIVE: Hepatic encephalopathy (HE) is a neuropsychiatric syndrome resulting from liver failure. In the present study, we aimed to standardize an animal model of HE induced by thioacetamide (TAA) in C57BL/6 mice evaluating behavioral symptoms in ...
Aline Silva de Miranda   +9 more
doaj   +1 more source

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